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Dorsal Column–medial Lemniscus Pathway
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints. It transmits this information to the somatosensory cortex of the postcentral gyrus in the parietal lobe of the brain.O'Sullivan, S. B., & Schmitz, T. J. (2007). Physical Rehabilitation (5th Edition ed.). Philadelphia: F.A. Davis Company. The pathway receives information from sensory receptors throughout the body, and carries this in the gracile fasciculus and the cuneate fasciculus, tracts that make up the white matter dorsal columns (also known as the posterior funiculi) of the spinal cord. At the level of the medulla oblongata, the fibers of the tracts decussate and are continued in the medial lemniscus, on to the thalamus and relayed from there through the inte ...
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Sensory Receptor
Sensory neurons, also known as afferent neurons, are neurons in the nervous system, that convert a specific type of stimulus, via their receptors, into action potentials or graded receptor potentials. This process is called sensory transduction. The cell bodies of the sensory neurons are located in the dorsal root ganglia of the spinal cord. The sensory information travels on the afferent nerve fibers in a sensory nerve, to the brain via the spinal cord. Spinal nerves transmit external sensations via sensory nerves to the brain through the spinal cord. The stimulus can come from exteroreceptors outside the body, for example those that detect light and sound, or from interoreceptors inside the body, for example those that are responsive to blood pressure or the sense of body position. Types and function Sensory neurons in vertebrates are predominantly pseudounipolar or bipolar, and different types of sensory neurons have different sensory receptors that respond to ...
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Cuneate Fasciculus
Cuneate means "wedge-shaped", and can apply to: * Cuneate leaf, a leaf shape * Cuneate nucleus The dorsal column nuclei are a pair of nuclei in the dorsal columns of the dorsal column–medial lemniscus pathway (DCML) in the brainstem. The name refers collectively to the cuneate nucleus and gracile nucleus, which are situated at the l ..., a part of the brainstem * Cuneate fasciculus, a tract from the spinal cord into the brainstem {{disambiguation ...
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Sensory Neuron
Sensory neurons, also known as afferent neurons, are neurons in the nervous system, that convert a specific type of stimulus, via their receptors, into action potentials or graded receptor potentials. This process is called sensory transduction. The cell bodies of the sensory neurons are located in the dorsal root ganglia of the spinal cord. The sensory information travels on the afferent nerve fibers in a sensory nerve, to the brain via the spinal cord. Spinal nerves transmit external sensations via sensory nerves to the brain through the spinal cord. The stimulus can come from exteroreceptors outside the body, for example those that detect light and sound, or from interoreceptors inside the body, for example those that are responsive to blood pressure or the sense of body position. Types and function Sensory neurons in vertebrates are predominantly pseudounipolar or bipolar, and different types of sensory neurons have different sensory receptors that respond t ...
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Second-order Neuron
Second-order may refer to: Mathematics * Second order approximation, an approximation that includes quadratic terms * Second-order arithmetic, an axiomatization allowing quantification of sets of numbers * Second-order differential equation, a differential equation in which the highest derivative is the second * Second-order logic, an extension of predicate logic * Second-order perturbation, in perturbation theory Science and technology * Second-order cybernetics, the recursive application of cybernetics to itself and the reflexive practice of cybernetics according to this critique. * Second-order fluid Second-order may refer to: Mathematics * Second order approximation, an approximation that includes quadratic terms * Second-order arithmetic, an axiomatization allowing quantification of sets of numbers * Second-order differential equation, a di ..., an extension of fluid dynamics * Second order Fresnel lens, a size of lighthouse lens * Second-order reaction, a reaction in w ...
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First-order Neuron
In mathematics and other formal sciences, first-order or first order most often means either: * "linear" (a polynomial of degree at most one), as in first-order approximation and other calculus uses, where it is contrasted with "polynomials of higher degree", or * "without self-reference", as in first-order logic and other logic uses, where it is contrasted with "allowing some self-reference" (higher-order logic) In detail, it may refer to: Mathematics * First-order approximation * First-order arithmetic * First-order condition * First-order hold, a mathematical model of the practical reconstruction of sampled signals * First-order inclusion probability * First Order Inductive Learner, a rule-based learning algorithm * First-order reduction, a very weak type of reduction between two computational problems * First-order resolution * First-order stochastic dominance * First order stream Differential equations * Exact first-order ordinary differential equation * First-o ...
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Brainstem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory system, respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the b ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. The spinal cord is also covered by meninges and enclosed by the neural arches. Together, the brain and spinal cord make up the central nervous system. In humans, the spinal cord is a continuation of the brainstem and anatomically begins at the occipital bone, passing out of the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it tapers to become the cauda equina. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diam ...
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Internal Capsule
The internal capsule is a paired white matter structure, as a two-way nerve tract, tract, carrying afferent nerve fiber, ascending and efferent nerve fiber, descending axon, fibers, to and from the cerebral cortex. The internal capsule is situated in the Anatomical terms of location#Medial and lateral, inferomedial part of each cerebral hemisphere of the brain. It carries information past the subcortical basal ganglia. As it courses it separates the caudate nucleus and the thalamus from the putamen and the globus pallidus. It also separates the caudate nucleus and the putamen in the dorsal striatum, a brain region involved in motor and reward pathways. The internal capsule is V-shaped in transection forming an anterior and posterior limb, with the angle between them called the genu. The corticospinal tract constitutes a large part of the internal capsule, carrying motor information from the primary motor cortex to the lower motor neurons in the spinal cord. Above the basal gangli ...
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Thalamus
The thalamus (: thalami; from Greek language, Greek Wikt:θάλαμος, θάλαμος, "chamber") is a large mass of gray matter on the lateral wall of the third ventricle forming the wikt:dorsal, dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, known as the thalamocortical radiations, allowing hub (network science), hub-like exchanges of information. It has several functions, such as the relaying of sensory neuron, sensory and motor neuron, motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, the thalami are paramedian symmetrical structures (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalami ar ...
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Medial Lemniscus
The medial lemniscus, also known as Reil's band or Reil's ribbon (for German anatomist Johann Christian Reil), is a large ascending bundle of heavily myelinated axons that decussate in the brainstem The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is conti ..., specifically in the medulla oblongata. The medial lemniscus is formed by the crossings of the internal arcuate fibers. The internal arcuate fibers are composed of axons of the gracile nucleus and the cuneate nucleus. The cell bodies of the nuclei lie contralaterally. The medial lemniscus is part of the somatosensory dorsal column–medial lemniscus pathway, which ascends in the spinal cord to the thalamus.Kamali A, Kramer LA, Butler IJ, Hasan KM. Diffusion tensor tractography of the somatosensory system in the human brains ...
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Sensory Decussation
The sensory decussation or decussation of the lemnisci is a decussation (a crossing over) of axons from the gracile nucleus and cuneate nucleus, known together as the dorsal column nuclei. The dorsal column nuclei are responsible for fine touch, vibration, proprioception and two-point discrimination. The fibers of this decussation are called the internal arcuate fibers and are found at the superior aspect of the closed medulla oblongata, superior to the motor decussation. Neurons of these nuclei are second-order neurons in the dorsal column–medial lemniscus pathway. Structure At the level of the closed medulla in the posterior white column, two large nuclei namely the gracile nucleus and the cuneate nucleus can be found. The two nuclei receive the impulse from the two ascending tracts: fasciculus gracilis and fasciculus cuneatus. After the two tracts terminate upon these nuclei, the heavily myelinated fibres arise and ascend anteromedially around the periaqueducta ...
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