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Dopamine Withdrawal Syndrome
Dopamine dysregulation syndrome (DDS) is a dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended length of time. It is characterized by severely disinhibited patterns of behavior, leading to problems such as addiction to the offending medication, gambling addiction, or compulsive sexual behavior, along with a general orientation towards immediate gratification. It typically occurs in people with Parkinson's disease (PD) or restless legs syndrome (RLS) who have taken dopamine agonist medications for an extended period of time. Signs and symptoms The most common symptom is craving for the dopaminergic medication. However, other behavioral symptoms can appear independently of cravings or co-occur with it. Cravings are an intense impulse of the subject to obtain medication even in the absence of symptoms that indicate its intake. To fulfill this need, the person will self-administer extra doses. When self-administration is not p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeletal Formula
The skeletal formula, line-angle formula, bond-line formula or shorthand formula of an organic compound is a type of minimalist structural formula representing a molecule's Atom, atoms, structural isomer, bonds and some details of its molecular geometry, geometry. The lines in a skeletal formula represent bonds between carbon atoms, unless labelled with another element. Labels are optional for carbon atoms, and the hydrogen atoms attached to them. An early form of this representation was first developed by organic chemist August Kekulé, while the modern form is closely related to and influenced by the Lewis structure of molecules and their valence electrons. Hence they are sometimes termed Kekulé structures or Lewis–Kekulé structures. Skeletal formulas have become ubiquitous in organic chemistry, partly because they are relatively quick and simple to draw, and also because the Arrow pushing, curved arrow notation used for discussions of reaction mechanisms and Resonance ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Problem Gambling
Problem gambling, ludopathy, or ludomania is repetitive gambling behavior despite harm and negative consequences. Problem gambling may be diagnosed as a mental disorder according to DSM-5 if certain diagnostic criteria are met. Pathological gambling is a common disorder associated with social and family costs. The DSM-5 has re-classified the condition as an addictive disorder, with those affected exhibiting many similarities to those with substance addictions. The term ''gambling addiction'' has long been used in the recovery movement. Pathological gambling was long considered by the American Psychiatric Association to be an impulse-control disorder rather than an addiction. However, data suggests a closer relationship between pathological gambling and substance use disorders than exists between PG and obsessive–compulsive disorder, mainly because the behaviors in problem gambling and most primary substance use disorders (i.e., those not resulting from a desire to " sel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grandiosity
In psychology, grandiosity is a sense of superiority, uniqueness, or invulnerability that is unrealistic and not based on personal capability. It may be expressed by exaggerated beliefs regarding one's abilities, the belief that few other people have anything in common with oneself, and that one can only be understood by a few, very special people. Grandiosity is a core diagnostic criterion for hypomania/mania in bipolar disorder and narcissistic personality disorder.Diagnostic and Statistical Manual of Mental Disorders Fourth edition, Text Revision (DSM-IV-TR) American Psychiatric Association (2000) Measurement Few scales exist for the sole purpose of measuring grandiosity, though one recent attempt is the Narcissistic Grandiosity Scale (NGS), an adjective rating scale where one indicates the applicability of a word to oneself (e.g. superior, glorious). Grandiosity is also measured as part of other tests, including the Specific Psychotic Experiences Questionnaire (SPEQ), Perso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Omnipotence
Omnipotence is the property of possessing maximal power. Monotheistic religions generally attribute omnipotence only to the deity of their faith. In the monotheistic religious philosophy of Abrahamic religions, omnipotence is often listed as one of God's characteristics, along with omniscience, omnipresence, and omnibenevolence. Etymology The word ''omnipotence'' derives from the Latin prefix ''omni''-, meaning "all", and the word ''potens'', meaning "potent" or "powerful". Thus the term means "all-powerful". Meanings Scholasticism The term omnipotent has been used to connote a number of different positions. These positions include, but are not limited to, the following: # A deity is able to do anything that it chooses to do. (In this version, God can do the impossible and something contradictory.) # A deity is able to do anything that is in accord with its own nature (thus, for instance, if it is a logical consequence of a deity's nature that what it speaks is truth, then i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphoria (emotion)
Euphoria ( ) is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Certain natural rewards and social activities, such as aerobic exercise, laughter, listening to or making music and dancing, can induce a state of euphoria. Euphoria is also a symptom of certain neurological or neuropsychiatric disorders, such as mania. Romantic love and components of the human sexual response cycle are also associated with the induction of euphoria. Certain drugs, many of which are addictive, can cause euphoria, which at least partially motivates their recreational use. Hedonic hotspots – i.e., the pleasure centers of the brain – are functionally linked. Activation of one hotspot results in the recruitment of the others. Inhibition of one hotspot results in the blunting of the effects of activating another hotspot. Therefore, the simultaneous activation of every hedonic hotspot within the reward system is believed to be nece ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypomania
Hypomania (literally "under mania" or "less than mania") is a Psychiatry, psychiatric Abnormality (behavior), behavioral syndrome characterized essentially by an apparently non-contextual elevation of Mood (psychology), mood (i.e., euphoria) that contributes to persistently disinhibition, disinhibited behavior. The individual with the condition may experience irritability, not necessarily less severe than full mania; in fact, the presence of marked irritability is a documented feature of hypomanic and Mixed affective state, mixed episodes in bipolar II disorder. According to DSM-5 criteria, hypomania is distinct from mania in that there is no significant functional impairment; mania, by DSM-5 definition, does include significant functional impairment and may have psychotic features. Characteristic behaviors of people experiencing hypomania are a notable decrease in the need for sleep, an overall increase in energy, unusual behaviors and actions, and a markedly distinctive incre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bribery
Bribery is the corrupt solicitation, payment, or Offer and acceptance, acceptance of a private favor (a bribe) in exchange for official action. The purpose of a bribe is to influence the actions of the recipient, a person in charge of an official duty, to act contrary to their duty and the known rules of honesty and integrity. Gifts of money or other items of value that are otherwise available to everyone on an equivalent basis, and not for dishonest purposes, are not bribery. Offering a discount or a refund to all purchasers is a rebate (marketing), rebate and is not bribery. For example, it is legal for an employee of a Public Utilities Commission involved in electric rate regulation to accept a rebate on electric service that reduces their cost of electricity, when the rebate is available to other residential electric customers; however, giving a discount specifically to that employee to influence them to look favorably on the electric utility's rate increase applications would ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malingering
Malingering is the fabrication, feigning, or exaggeration of physical or psychological symptoms designed to achieve a desired outcome, such as personal gain, relief from duty or work, avoiding arrest, receiving medication, or mitigating prison sentencing. It presents a complex ethical dilemma within domains of society, including healthcare, legal systems, and employment settings. Although malingering is not a medical diagnosis, it may be recorded as a "focus of clinical attention" or a "reason for contact with health services". It is coded by both the ICD-10 and DSM-5. The intent of malingerers vary. For example, the homeless may fake a mental illness to gain hospital admission. Impacts of failure to detect malingering are extensive, impacting insurance industries, healthcare systems, public safety, and veterans' disability benefits. Malingered behaviour typically ends as soon as the external goal is obtained. Malingering is established as separate from similar forms of excessive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aggression
Aggression is behavior aimed at opposing or attacking something or someone. Though often done with the intent to cause harm, some might channel it into creative and practical outlets. It may occur either reactively or without provocation. In humans, aggression can be caused by various triggers. For example, built-up frustration due to blocked goals or perceived disrespect. Human aggression can be classified into direct and indirect aggression; while the former is characterized by physical or verbal behavior intended to cause harm to someone, the latter is characterized by behavior intended to harm the social relations of an individual or group. In definitions commonly used in the social sciences and behavioral sciences, aggression is an action or response by an individual that delivers something unpleasant to another person. Some definitions include that the individual must intend to harm another person. In an interdisciplinary perspective, aggression is regarded as "an ensem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Slot Machine
A slot machine, fruit machine (British English), poker machine or pokie (Australian English and New Zealand English) is a gambling machine that creates a game of chance for its customers. A slot machine's standard layout features a screen displaying three or more reels that "spin" when the game is activated. Some modern slot machines still include a lever as a skeuomorphic design trait to trigger play. However, the mechanical operations of early machines have been superseded by random number generators, and most are now operated using buttons and touchscreens. Slot machines include one or more currency detectors that validate the form of payment, whether coin, banknote, voucher, or token. The machine pays out according to the pattern of symbols displayed when the reels stop "spinning". Slot machines are the most popular gambling method in casinos and contribute about 70% of the average U.S. casino's income. Digital technology has resulted in variations in the original slo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Punding
Punding is compulsive performance of repetitive, mechanical tasks, such as assembling and disassembling, collecting, or sorting objects. It can also apply to digital objects, such as computer files and data. The term was originally coined to describe complex, prolonged, purposeless (unproductive), and stereotyped behaviour in phenmetrazine and chronic amphetamine users, by Swedish forensic psychiatrist G. Rylander, in 1968. It was later described in Parkinson's disease, but mainly in cases of patients being treated with dopaminergic drugs. It has also been described in methamphetamine and cocaine users, as well as in some patients with gambling addictions, and hypersexuality. For example, punding may consist of activities such as collecting pebbles and lining them up as perfectly as possible; disassembling and reassembling wristwatches; or conducting extended monologues devoid of context. People engaging in punding find immersion in such activities comforting, even when it serve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dopamine Agonist
A dopamine agonist is a compound that activates dopamine receptors. There are two families of dopamine receptors, D1-like and D2-like. They are all G protein-coupled receptors. D1- and D5-receptors belong to the D1-like family and the D2-like family includes D2, D3 and D4 receptors. Dopamine agonists are primarily used in the treatment of the motor symptoms of Parkinson's disease, and to a lesser extent, in hyperprolactinemia and restless legs syndrome. They are also used off-label in the treatment of clinical depression. Impulse control disorders are associated with the use of dopamine agonists. Medical uses Parkinson's disease Dopamine agonists are mainly used in the treatment of Parkinson's disease. The cause of Parkinson's is not fully known but genetic factors, for example specific genetic mutations, and environmental triggers have been linked to the disease. In Parkinson's disease dopaminergic neurons that produce the neurotransmitter dopamine in the brain slowly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
