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Dimethylethanolamine
Dimethylethanolamine (DMAE or DMEA) is an organic compound with the formula (CH3)2NCH2CH2OH. It is bifunctional, containing both a tertiary amine and primary alcohol functional groups. It is a colorless viscous liquid. It is used in skin care products for improving skin tone and also taken orally as a nootropic. It is prepared by the ethoxylation of dimethylamine. Industrial uses Dimethylaminoethanol is used as a curing agent for polyurethanes and epoxy resins. It is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride. The acrylate ester is used as a flocculating agent. Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams. Nutraceutical uses The bitartrate salt of DMAE, i.e. 2-dimethylaminoethanol (+)-bitartrate, is sold as a dietary supplement. It is a white powder providing 37% DMAE. Animal tests show possible benefit for improving spatial memory and working memory.Edward D Levin, Jed E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Methylethanolamine
''N''-Methylethanolamine is an alkanolamine with the formula CH3NHCH2CH2OH. It is flammable, corrosive, colorless, viscous liquid.Matthias Frauenkron, Johann-Peter Melder, Günther Ruider, Roland Rossbacher, Hartmut Höke "Ethanolamines and Propanolamines" in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2002, Wiley-VCH, Weinheim. It is an intermediate in the biosynthesis of choline. With both an amine and a hydroxyl functional groups, it is a useful intermediate in the chemical synthesis of various products including polymers and pharmaceuticals. It is also used as a solvent, for example in the processing of natural gas, where it is used together with its analogs ethanolamine and dimethylethanolamine. Production ''N''-Methylethanolamine is produced industrially by reacting ethylene oxide with excess methylamine in aqueous solution. This reaction yields a mixture of the 1:1 addition product NMEA (1) and - by a further addition of another ethylene oxide - the 1:2 additio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meclofenoxate
Meclofenoxate (INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA). In elderly patients, meclofenoxate has been shown to improve performance on certain memory tests. Meclofenoxate also increases cellular membrane phospholipids. It is sold in Japan and some European countries, such as Germany, Hungary, and Austria, as a prescription drug. Side effects Meclofenoxate is considered to be very safe and high in tolerability. However, possible side effects may include, rarely, insomnia, dizziness, restlessness, muscle tremor, depression, nausea, muscle tension, and headache; these side effects may be due to overdosage and may indicate the need for the dosage to be reduced. Research Meclofenoxate, as well as DMAE, have been found to increase the lifespans of mice by 26.5%. Brand names In addition to Lucidril, meclofenoxate has also b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corrosion Inhibitors
In chemistry, a corrosion inhibitor or anti-corrosive is a chemical compound that, when added to a liquid or gas, decreases the corrosion rate of a material, typically a metal or an alloy, that comes into contact with the fluid. The effectiveness of a corrosion inhibitor depends on fluid composition, quantity of water, and flow regime. Corrosion inhibitors are common in industry, and also found in over-the-counter products, typically in spray form in combination with a lubricant and sometimes a penetrating oil. They may be added to water to prevent leaching of lead or copper from pipes. A common mechanism for inhibiting corrosion involves formation of a coating, often a passivation layer, which prevents access of the corrosive substance to the metal. Permanent treatments such as chrome plating are not generally considered inhibitors, however: corrosion inhibitors are additives to the fluids that surround the metal or related object. Types The nature of the corrosive inhib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,N-Diisopropylaminoethanol
''N'',''N''-Diisopropylaminoethanol (DIPA) is a processor for production of various chemicals and also an intermediate in the production of the nerve agent Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that ...s VX and NX. It is a colorless liquid, although aged samples can appear yellow. Health effects Inhalation and skin contact are expected to be the primary ways of occupational exposure to this chemical. Based on single exposure animal tests, it is considered to be slightly toxic if swallowed or inhaled, moderately toxic if absorbed through skin as well as being corrosive to eyes and skin. Vapor may be irritating to the eyes and upper respiratory tract. Temporary and reversible visual disturbances characterized by mildly blurred vision, a blue-gray discolorization of sight (blu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bitartrate
, Section2 = {{Chembox Properties , C=4 , H=5 , O=6 , Formula_Charge = − , ConjugateAcid = Tartaric acid , ConjugateBase = Tartrate Bitartrate is an anion which is the conjugate base of tartaric acid. It may also refer to any salt or monoester In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides ... of tartaric acid. Some examples of bitartrate salts include: * Choline bitartrate * Cysteamine bitartrate * Dihydrocodeine bitartrate * Dimethylaminoethanol bitartrate * Hydrocodone bitartrate * Metaraminol bitartrate * Norepinephrine bitartrate * Potassium bitartrate * Sodium bitartrate References Tartrates ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nootropics
Nootropics ( , or ) (colloquial: smart drugs and cognitive enhancers, similar to adaptogens) are a wide range of natural or synthetic supplements or drugs and other substances that are claimed to improve cognitive function or to promote relaxation, particularly boosting mood, executive functions, attention, memory, creativity, or motivation in healthy individuals. The use of cognition-enhancing supplements by healthy individuals in the absence of a medical indication spans numerous controversial issues, including the ethics and fairness of their use, concerns over adverse effects, and the diversion of prescription drugs for non-medical uses. Nonetheless, the international sales of cognitive- or mood-enhancing supplements have continued to grow over time and in 2012 reached 0.69 billion. With sales supported by global health trends, the market is expected to reach US$33.85 billion by the year 2030, at a CAGR of 14.8%. While most nootropics are not regulated, there are oth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cholinergics
Cholinergic agents are compounds which mimic the action of acetylcholine and/or butyrylcholine. In general, the word "choline" describes the various quaternary ammonium salts containing the ''N'',''N'',''N''-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin. Choline also prevents fat deposits in the liver and facilitates the movement of fats into cells. The parasympathetic nervous system, which uses acetylcholine almost exclusively to send its messages, is said to be almost entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic, as are the receptor for the merocrine sweat glands. In neuroscience and related fields, the term cholinergic is used in these related contexts: * A substance (or ligand) is cholinergic if it i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primary Alcohols
A primary alcohol is an alcohol in which the hydroxy group is bonded to a primary carbon atom. It can also be defined as a molecule containing a “–CH2OH” group. In contrast, a secondary alcohol has a formula “–CHROH” and a tertiary alcohol has a formula “–CR2OH”, where “R” indicates a carbon-containing group. Examples of primary alcohols include ethanol and 1-butanol. Methanol is also generally regarded as a primary alcohol, including the 1911 edition of the Encyclopædia Britannica,. See also * Alcohol (especially Nomenclature section for discussion on Secondary and Tertiary alcohols.) * Oxidation of primary alcohols to carboxylic acids The oxidation of primary alcohols to carboxylic acids is an important oxidation Redox (reduction–oxidation, , ) is a type of chemical reaction in which the oxidation states of substrate change. Oxidation is the loss of electrons or an ... References {{organic-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dimethylamino Compounds
Dimethylamine is an organic compound with the formula (CH3)2NH. This secondary amine is a colorless, flammable gas with an ammonia-like odor. Dimethylamine is commonly encountered commercially as a solution in water at concentrations up to around 40%. An estimated 270,000 tons were produced in 2005. Structure and synthesis The molecule consists of a nitrogen atom with two methyl substituents and one proton. Dimethylamine is a weak base and the pKa of the ammonium CH3--CH3 is 10.73, a value above methylamine (10.64) and trimethylamine (9.79). Dimethylamine reacts with acids to form salts, such as dimethylamine hydrochloride, an odorless white solid with a melting point of 171.5 °C. Dimethylamine is produced by catalytic reaction of methanol and ammonia at elevated temperatures and high pressure: :2 CH3OH + NH3 → (CH3)2NH + 2 H2O Natural occurrence Dimethylamine is found quite widely distributed in animals and plants, and is present in many foods at the lev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orphenadrine
Orphenadrine (sold under many brand names) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs. This substance is considered a dirty drug due to its multiple mechanism of action in different pathways. It was discovered and developed in the 1940s. Medical use Orphenadrine is a skeletal muscle relaxant. It is used to relieve pain caused by muscle injuries such as strains and sprains, in combination with rest and physical therapy. A 2004 review found fair evidence that orphenadrine is effective for acute back or neck pain, but found insufficient evidence to establish the relative efficacy of the drug in relation to other drugs in the study. Orphenadrine and other muscle relaxants are sometimes used to treat pain arising from rheumatoid arthritis but there is no ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diethanolamine
Diethanolamine, often abbreviated as DEA or DEOA, is an organic compound with the formula HN(CH2CH2OH)2. Pure diethanolamine is a white solid at room temperature, but its tendencies to absorb water and to supercool meaning that it is often encountered as a colorless, viscous liquid. Diethanolamine is polyfunctional, being a secondary amine and a diol. Like other organic amines, diethanolamine acts as a weak base. Reflecting the hydrophilic character of the secondary amine and hydroxyl groups, DEA is soluble in water. Amides prepared from DEA are often also hydrophilic. In 2013, the chemical was classified by the International Agency for Research on Cancer as "possibly carcinogenic to humans" ( Group 2B). Production The reaction of ethylene oxide with aqueous ammonia first produces ethanolamine: :C2H4O + NH3 → H2NCH2CH2OH which reacts with a second and third equivalent of ethylene oxide to give DEA and triethanolamine: :C2H4O + H2NCH2CH2OH → HN(CH2CH2OH)2 :C2H4O + HN ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethanolamine
Ethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is an organic chemical compound with the formula or . The molecule is bifunctional, containing both a primary amine and a primary alcohol. Ethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia.. ETA molecules are a component in the formation of cellular membranes and are thus a molecular building block for life. It was thought to exist only on Earth and on certain asteroids, but in 2021 evidence was found that ETA molecules exist in interstellar space. Derivatives of ethanolamine are widespread in nature; e.g., lipids, as precursor of a variety of ''N''-acylethanolamines (NAEs), that modulate several animal and plant physiological processes such as seed germination, plant–pathogen interactions, chloroplast development and flowering, as well as precursor, combined with arachidonic acid 20: 4, ω-6), to form the endocannabinoid anandamide (AEA: ; 20:4, ω-6). The ethanolamines comprise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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