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Dihydrobenzophenanthridine Oxidase
Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme. In the IUBMB Enzyme Nomenclature, dihydrobenzophenanthridine oxidase is . Dihydrobenzophenanthridine oxidase produces oxidized forms of benzophenanthridine alkaloids: * In ''Sanguinaria canadensis'' (bloodroot), dihydrobenzophenanthridine oxidase produces sanguinarine from dihydrosanguinarine, and chelirubine from dihydrochelirubine. * In ''Eschscholzia californica ''Eschscholzia californica'', the California poppy, golden poppy, Mexican poppy, California sunlight or cup of gold, is a species of flowering plant in the family Papaveraceae, native to the United States and Mexico. It is cultivated as an orn ...'' (California poppy), dihydrobenzophenanthridine oxidase produces macarpine from dihydromacarpine. External links Chelirubine, Macarpine and Sanguinarine Biosynthesis* * * KEGG (Kyoto Encyclopedia of Genes and Genomes) Alkaloid biosynthesis I - Reference pathway EC 1.5.3 {{1.5-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sanguinaria Canadensis
''Sanguinaria canadensis'', bloodroot, is a perennial, herbaceous flowering plant native to eastern North America. It is the only species in the genus ''Sanguinaria'', included in the poppy family Papaveraceae, and is most closely related to '' Eomecon'' of eastern Asia. ''Sanguinaria canadensis'' is sometimes known as Canada puccoon, bloodwort, redroot, red puccoon, and black paste. Plants are variable in leaf and flower shape, and have been separated as a different subspecies due to these variable shapes, indicating a highly variable species. In bloodroot, the sap is red and poisonous. Products made from sanguinaria extracts, such as black salve, are escharotic and can cause permanent disfiguring scarring. If applied to the skin, the extract sanguinarine may cause a massive scab of dead flesh where it killed the cells, called an ''eschar''. Although there are laboratory studies indicating that sanguinaria may have potential in cancer therapy, clinical studies are lacki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sanguinarine
Sanguinarine is a polycyclic quaternary alkaloid. It is extracted from some plants, including the bloodroot plant, from whose scientific name, ''Sanguinaria canadensis,'' its name is derived; the Mexican prickly poppy (''Argemone mexicana''); ''Chelidonium majus;'' and ''Macleaya cordata.'' Toxicity Sanguinarine is a toxin that kills animal cells through its action on the Na+/K+-ATPase, Na+/K+-ATPase transmembrane protein. Epidemic dropsy is a disease that results from ingesting sanguinarine. If applied to the skin, sanguinarine may cause a massive scab of dead flesh where it killed the cells where it was applied, called an ''eschar''. For this reason, sanguinarine is termed an escharotic. It is said to be 2.5 times more toxic than dihydrosanguinarine. Alternative medicine Native Americans once used sanguinarine in the form of bloodroot as a medical remedy, believing it had curative properties as an emetic, respiratory aid, and for a variety of ailments. In Colonial America ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dihydrosanguinarine
Dihydrosanguinarine is an alkaloid found in the herbs '' Corydalis adunca'' and ''Lamprocapnos spectabilis''.Israilov I, Melikov F, Murav'eva D. Alkaloids of Dicentra. Chem Nat Compd 1984; 20:74–76. See also * Dihydrosanguinarine 10-monooxygenase * Epidemic dropsy * Sanguinarine Sanguinarine is a polycyclic quaternary alkaloid. It is extracted from some plants, including the bloodroot plant, from whose scientific name, ''Sanguinaria canadensis,'' its name is derived; the Mexican prickly poppy (''Argemone mexicana''); ''C ... References Benzodioxoles Quinoline alkaloids Heterocyclic compounds with 6 rings Tetrahydroisoquinoline alkaloids {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eschscholzia Californica
''Eschscholzia californica'', the California poppy, golden poppy, Mexican poppy, California sunlight or cup of gold, is a species of flowering plant in the family Papaveraceae, native to the United States and Mexico. It is cultivated as an ornamental plant flowering in summer (spring in southern Australia), with showy flowers in brilliant shades of red, orange and yellow (occasionally pink and white). It is also used as food or a garnish. It had various uses in indigenous herbalism. It became the official state flower of California in 1903. Description California poppy is a perennial or annual plant growing to tall with alternately branching glaucous blue-green foliage. The leaves are alternately divided into round, lobed segments. The flowers are solitary on long stems, silky-textured, with four petals, each petal long and broad; flower color ranges through yellow, orange and red. Flowering occurs from February to September in the northern hemisphere. The petals close a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytochemistry (journal)
''Phytochemistry'' is a Peer review, peer-reviewed scientific journal covering pure and applied plant chemistry, plant biochemistry and molecular biology. It is published by Elsevier and is an official publication for the Phytochemical Society of Europe, the Phytochemical Society of North America, and the Phytochemical Society of Asia. A sister journal ''Phytochemistry Letters'' is published since 2008. Abstracting and indexing ''Phytochemistry'' is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.072. References External links *{{Official website, http://www.journals.elsevier.com/phytochemistry/ Biochemistry journals Botany journals Elsevier academic journals English-language journals Academic journals established in 1961 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
