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Differentiation
Differentiation may refer to: Business * Differentiation (economics), the process of making a product different from other similar products * Product differentiation, in marketing * Differentiated service, a service that varies with the identity of the consumer or the context in which the service is used Science, technology, and mathematics Biology and medicine * Cellular differentiation, in biology * ''Differentiation'' (journal), a peer-reviewed academic journal covering cell differentiation and cell development * Developmental biology, the study of the process by which animals and plants grow and develop * Differentiation therapy, a cancer treatment in which malignant cells are encouraged to differentiate into more mature forms using pharmacological agents Geology * Igneous differentiation, in geology * Planetary differentiation, in planetary science and geology Social sciences * Differentiation (economics), the process of making a product different from other similar prod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cellular Differentiation
Cellular differentiation is the process in which a stem cell alters from one type to a differentiated one. Usually, the cell changes to a more specialized type. Differentiation happens multiple times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Although metabolic composition does get altered quite dramatically ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation (economics)
In economics and marketing, product differentiation (or simply differentiation) is the process of distinguishing a product or service from others to make it more attractive to a particular target market. This involves differentiating it from competitors' products as well as from a firm's other products. The concept was proposed by Edward Chamberlin in his 1933 book, ''The Theory of Monopolistic Competition''. Rationale Firms have different resource endowments that enable them to construct specific competitive advantages over competitors. Resource endowments allow firms to be different, which reduces competition and makes it possible to reach new segments of the market. Thus, differentiation is the process of distinguishing the differences of a product or offering from others, to make it more attractive to a particular target market. Although research in a niche market may result in changing a product in order to improve differentiation, the changes themselves are not diffe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Product Differentiation
In economics and marketing, product differentiation (or simply differentiation) is the process of distinguishing a product or service from others to make it more attractive to a particular target market. This involves differentiating it from competitors' products as well as from a firm's other products. The concept was proposed by Edward Chamberlin in his 1933 book, ''The Theory of Monopolistic Competition''. Rationale Firms have different resource endowments that enable them to construct specific competitive advantages over competitors. Resource endowments allow firms to be different, which reduces competition and makes it possible to reach new segments of the market. Thus, differentiation is the process of distinguishing the differences of a product or offering from others, to make it more attractive to a particular target market. Although research in a niche market may result in changing a product in order to improve differentiation, the changes themselves are not di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation (sociology)
In system theory. "differentiation" is the increase of subsystems in a modern society to increase the complexity of a society. Each subsystem can make different connections with other subsystems, and this leads to more variation within the system in order to respond to variation in the environment. Differentiation that leads to more variation allows for better responses to the environment, and also for faster evolution (or perhaps sociocultural evolution), which is defined sociologically as a process of selection from variation; the more differentiation (and thus variation) that is available, the better the selection. Introduction Talcott Parsons was the first major theorist to develop a theory of society consisting of functionally defined sub-system, which emerges from an evolutionary point of view through a cybernetic process of differentiation. Niklas Luhmann, who studied under Talcott Parsons, took the latter's model and changed it in significant ways. Parsons regarded ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Igneous Differentiation
In geology, igneous differentiation, or magmatic differentiation, is an umbrella term for the various processes by which magmas undergo bulk chemical change during the partial melting process, cooling, emplacement, or eruption. The sequence of (usually increasingly silicic) magmas produced by igneous differentiation is known as a magma series. Definitions Primary melts When a rock melts to form a liquid, the liquid is known as a ''primary melt''. Primary melts have not undergone any differentiation and represent the starting composition of a magma. In nature, primary melts are rarely seen. Some leucosomes of migmatites are examples of primary melts. Primary melts derived from the mantle are especially important and are known as ''primitive melts'' or primitive magmas. By finding the primitive magma composition of a magma series, it is possible to model the composition of the rock from which a melt was formed, which is important because we have little direct evidence of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation (mathematics)
In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output value) with respect to a change in its argument (input value). Derivatives are a fundamental tool of calculus. For example, the derivative of the position of a moving object with respect to time is the object's velocity: this measures how quickly the position of the object changes when time advances. The derivative of a function of a single variable at a chosen input value, when it exists, is the slope of the tangent line to the graph of the function at that point. The tangent line is the best linear approximation of the function near that input value. For this reason, the derivative is often described as the "instantaneous rate of change", the ratio of the instantaneous change in the dependent variable to that of the independent variable. Derivatives can be generalized to functions of several real variables. In this generalization, the derivat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Planetary Differentiation
In planetary science, planetary differentiation is the process by which the chemical elements of a planetary body accumulate in different areas of that body, due to their physical or chemical behavior (e.g. density and chemical affinities). The process of planetary differentiation is mediated by partial melting with heat from radioactive isotope decay and planetary accretion. Planetary differentiation has occurred on planets, dwarf planets, the asteroid 4 Vesta, and natural satellites (such as the Moon). Physical differentiation Gravitational separation High-density materials tend to sink through lighter materials. This tendency is affected by the relative structural strengths, but such strength is reduced at temperatures where both materials are plastic or molten. Iron, the most common element that is likely to form a very dense molten metal phase, tends to congregate towards planetary interiors. With it, many siderophile elements (i.e. materials that readily alloy with iron) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryonic development of animals are: tissue patterning (via regional specification and patterned cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing to a specific region or part of the organism. These are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiated Instruction
Differentiated instruction and assessment, also known as differentiated learning or, in education, simply, differentiation, is a framework or philosophy for effective teaching that involves providing all students within their diverse classroom community of learners a range of different avenues for understanding new information (often in the same classroom) in terms of: acquiring content; processing, constructing, or making sense of ideas; and developing teaching materials and assessment measures so that all students within a classroom can learn effectively, regardless of differences in their ability.Differentiated instruction means using different tools, content, and due process in order to successfully reach all individuals. Differentiated instruction, according to Carol Ann Tomlinson, is the process of "ensuring that what a student learns, how he or she learns it, and how the student demonstrates what he or she has learned is a match for that student's readiness level, interests, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation (journal)
''Differentiation'' is a peer-reviewed academic journal covering cell differentiation and cell development. It was established in 1973 and is published 10 times per year by Elsevier, on behalf of the International Society of Differentiation. The editor-in-chief is Colin Stewart (Agency for Science, Technology and Research). According to the ''Journal Citation Reports'', the journal has a 2016 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 2.567. References External links * International Society of Differentiation Molecular and cellular biology journals Developmental biology journals Publications established in 1973 Elsevier academic journals English-language journals {{Molec-cell-biology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation Of Measures (other)
In mathematics, differentiation of measures may refer to: * the problem of differentiation of integrals In mathematics, the problem of differentiation of integrals is that of determining under what circumstances the mean value integral of a suitable function on a small neighbourhood of a point approximates the value of the function at that point. ..., also known as the differentiation problem for measures; * the Radon–Nikodym derivative of one measure with respect to another. {{mathematical disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differentiation Therapy
Differentiation therapy is a method to treating advanced cancers in which malignant cells are encouraged to differentiate into more mature forms using pharmacological agents. The basis of the therapy stems from the tendency of malignant tumor cells to assume a less specialized, stem cell-like dedifferentiated state. Leukemia The approach was motivated by noticing that leukemia cells fail to differentiate and fully mature. By 2001 encouraging clinical results were seen. The first differentiation agent found to be successful was all-trans-retinoic acid (ATRA) in the treatment of acute promyelocytic leukemia (APL). Other cancers The process of cancer spreading (metastasis) involves tumour cells undergoing an epithelial-to-mesenchymal transition (EMT) to invade and spread, followed by a mesenchymal-to-epithelial transition (MET) at remote sites. Other agents investigated (pre-clinically) to encourage MET include cholera toxin (CTx) and forskolin Forskolin (coleonol) is a labdan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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