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Diastase
A diastase (; from Greek διάστασις, "separation") is any one of a group of enzymes that catalyses the breakdown of starch into maltose. Alpha amylase degrades starch to a mixture of the disaccharide maltose; the trisaccharide maltotriose, which contains three α (1-4)-linked glucose residues; and oligosaccharides, known as dextrins, that contain the α (1-6)-linked glucose branches. Diastase was the first enzyme discovered. It was extracted from malt solution in 1833 by Anselme Payen and Jean-François Persoz, chemists at a French sugar factory. The name "diastase" comes from the Greek word διάστασις (''diastasis'') (a parting, a separation), because when beer mash is heated, the enzyme causes the starch in the barley seed to transform quickly into soluble sugars and hence the husk to separate from the rest of the seed. Today, "diastase" refers to any α-, β-, or γ-amylase (all of which are hydrolases) that can break down carbohydrates. The commonly used -as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Takadiastase
Takadiastase is a form of diastase which results from the growth, development, and nutrition of a distinct microscopic fungus known as ''Aspergillus oryzae'' (Koji). Takadiastase is named after Jōkichi Takamine, who developed the method first used for its extraction. External links Jokichi Takamine Taka-Diastase, AdrenalineHistory of industrial property rights (Japan Patent Office The is a Japanese governmental agency in charge of industrial property right affairs, under the Ministry of Economy, Trade and Industry. The Japan Patent Office is located in Kasumigaseki, Chiyoda, Tokyo and is one of the world's largest pa ...) Development of Takadiastase Hydrolases {{Enzyme-stub ja:ジアスターゼ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anselme Payen
Anselme Payen (; 6 January 1795 – 12 May 1871) was a French chemist known for discovering the enzyme diastase, and the carbohydrate cellulose. Biography Payen was born in Paris. He began studying science with his father when he was a 13-year-old, and later studied Chemistry at the École Polytechnique under the chemists Louis Nicolas Vauquelin and Michel Eugène Chevreul. At the age of 23, Payen became manager of a borax-refining factory, where he developed a process for synthesizing borax from soda and boric acid. Previously, all borax had been imported from the East Indies exclusively by the Dutch. Payen's new method of synthesizing borax allowed him to sell the mineral at one third the going price, and break the Dutch monopoly. Payen also developed processes for refining sugar, along with a way to refine starch and alcohol from potatoes, and a method for determination of nitrogen. Payen invented a decolorimeter, which dealt with the analysis, decolorization, bleaching ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are Ribozyme, catalytic RNA molecules, called ribozymes. Enzymes' Chemical specificity, specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jean-François Persoz
Jean-François Persoz (9 June 1805–September 1868) was a French chemist known for discovering the enzyme diastase and on the properties of dextrin. He also wrote a report that coined the name cellulose. Born in Cortaillod, Persoz studied physical science in Paris under Louis Jacques Thénard and received his doctorate in 1833. Persoz was a professor of chemistry at the University of Strasbourg since 1833 and then a professor of dyeing and calico-printing at the Conservatoire des Arts et Metiers A music school is an educational institution specialized in the study, training, and research of music. Such an institution can also be known as a school of music, music academy, music faculty, college of music, music department (of a larger ins ... since 1852. His work on diastase, also known as amylase, was carried out in collaboration with Anselme Payen and published in 1833. His work on dextrin was carried out in collaboration with J.B. BiotBiot, J. B., Persoz, J.: Ann. Chim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amylase
An amylase () is an enzyme that catalyses the hydrolysis of starch (Latin ') into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase ( alpha amylase) to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. Specific amylase proteins are designated by different Greek letters. All amylases are glycoside hydrolases and act on α-1,4- glycosidic bonds. Classification α-Amylase The α-amylases () (CAS 9014-71-5) (alternative names: 1,4-α-D-glucan glucanohydrolase; glycogenase) are calcium metalloenzymes. By acting at ra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
-ase
The suffix -ase is used in biochemistry to form names of enzymes. The most common way to name enzymes is to add this suffix onto the end of the substrate, ''e.g.'' an enzyme that breaks down peroxides may be called peroxidase; the enzyme that produces telomeres is called telomerase. Sometimes enzymes are named for the function they perform, rather than substrate, e.g. the enzyme that polymerizes (assembles) DNA into strands is called polymerase; see also reverse transcriptase. The ''-ase'' suffix is a libfix derived from "diastase", the first recognized enzyme. Its usage in subsequently discovered enzymes was proposed by Émile Duclaux, with the intention of honoring the first scientists to isolate diastase. See also *Amylase *DNA polymerase A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whipple Disease
Whipple's disease is a rare systemic infectious disease caused by the bacterium '' Tropheryma whipplei''. First described by George Hoyt Whipple in 1907 and commonly considered as a gastrointestinal disorder, Whipple's disease primarily causes malabsorption, but may affect any part of the human body, including the heart, brain, joints, skin, lungs and the eyes. Weight loss, diarrhea, joint pain, and arthritis are common presenting symptoms, but the presentation can be highly variable in certain individuals, and about 15% of patients do not have the standard signs and symptoms. Whipple's disease is significantly more common in men, with 87% of patients diagnosed being male. When recognized and treated, Whipple's disease can usually be cured with long-term antibiotic therapy, but if the disease is left undiagnosed or untreated, it can ultimately be fatal. Signs and symptoms The most common symptoms are diarrhea, abdominal pain, weight loss, and joint pains. The joint pains may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Émile Duclaux
Émile Duclaux (24 June 1840 – May 2, 1904) was a French microbiologist and chemist born in Aurillac, Cantal. He studied at the College of Aurillac, the Lycée Saint-Louis in Paris and at École Normale Supérieure. In 1862 he began work as an assistant in the laboratory of Louis Pasteur (1822–1895). During his career, he taught classes in Tours (1865), Clermont-Ferrand (1866), Lyon (from 1873) and Paris (from 1878). In Paris, he was a professor of meteorology at the Institute of Agronomy. For much of his career he was associated with the work of Louis Pasteur. In 1888 he was elected to the ''Académie des sciences'', and in 1894 became a member of the ''Académie Nationale de Médecine''. Duclaux's work was largely in the fields of chemistry, bacteriology, hygiene and agriculture. Duclaux initiated the custom of naming enzymes by adding the suffix " -ase" to the enzyme's substrate. His intention was to honor the first scientists (namely Anselme Payen, 1795–1871; and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ATC Code
The Anatomical Therapeutic Chemical (ATC) Classification System is a drug classification system that classifies the active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties. Its purpose is an aid to monitor drug use and for research to improve quality medication use. It does not imply drug recommendation or efficacy. It is controlled by the World Health Organization Collaborating Centre for Drug Statistics Methodology (WHOCC), and was first published in 1976. Coding system This pharmaceutical coding system divides drugs into different groups according to the organ or system on which they act, their therapeutic intent or nature, and the drug's chemical characteristics. Different brands share the same code if they have the same active substance and indications. Each bottom-level ATC code stands for a pharmaceutically used substance, or a combination of substances, in a single indication ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periodic Acid–Schiff Stain
Periodicity or periodic may refer to: Mathematics * Bott periodicity theorem, addresses Bott periodicity: a modulo-8 recurrence relation in the homotopy groups of classical groups * Periodic function, a function whose output contains values that repeat periodically * Periodic mapping Physical sciences * Periodic table of chemical elements * Periodic trends, relative characteristics of chemical elements observed * Redshift periodicity, astronomical term for redshift quantization Other uses * Fokker periodicity blocks Fokker periodicity blocks are a concept in tuning theory used to mathematically relate musical intervals in just intonation to those in equal tuning. They are named after Adriaan Daniël Fokker. These are included as the primary subset of what ..., which mathematically relate musical intervals * Periodic acid, a compound of iodine * Principle of periodicity, a concept in generally accepted accounting principles * Quasiperiodicity, property of a system that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jaundice
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. The prevalence of jaundice in adults is rare, while jaundice in babies is common, with an estimated 80% affected during their first week of life. The most commonly associated symptoms of jaundice are itchiness, pale feces, and dark urine. Normal levels of bilirubin in blood are below 1.0 mg/ dl (17 μmol/ L), while levels over 2–3 mg/dl (34–51 μmol/L) typically result in jaundice. High blood bilirubin is divided into two types – unconjugated and conjugated bilirubin. Causes of jaundice vary from relatively benign to potentially fatal. High unconjugated bilirubin may be due to excess red blood cell breakdown, large bruises, genetic conditions su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Choledocholithiasis
Common bile duct stone, also known as choledocholithiasis, is the presence of gallstones in the common bile duct (CBD) (thus '' choledocho-'' + '' lithiasis''). This condition can cause jaundice and liver cell damage. Treatments include choledocholithotomy and endoscopic retrograde cholangiopancreatography (ERCP). Signs and symptoms Murphy's sign is commonly negative on physical examination in choledocholithiasis, helping to distinguish it from cholecystitis. Jaundice of the skin or eyes is an important physical finding in biliary obstruction. Jaundice and/or clay-colored stool may raise suspicion of choledocholithiasis or even gallstone pancreatitis. If the above symptoms coincide with fever and chills, the diagnosis of ascending cholangitis may also be considered. More than 70% of people with gallstones are asymptomatic and are diagnosed incidentally during ultrasound. Studies have shown that 10% of those with gallstones will develop symptoms within 5 years of diagnosis, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
