Deruxtecan
Deruxtecan is a chemical compound and a derivative of exatecan that acts as Topoisomerase inhibitor#Topoisomerase I inhibitors, topoisomerase I inhibitor. It is available linked to specific monoclonal antibody (antibody–drug conjugate), such as: * Trastuzumab deruxtecan. It is licensed for the treatment of breast cancer or gastric adenocarcinoma, gastric or gastroesophageal adenocarcinoma. * Patritumab deruxtecan, an experimental antibody–drug conjugate to treat non-small-cell lung cancer. * Ifinatamab deruxtecan, an experimental anti-cancer treatment. * Datopotamab deruxtecan (Datroway), used for the treatment of breast cancer References

{{Reflist Antibody-drug conjugates Topoisomerase inhibitors Carboxamides Nitrogen heterocycles Maleimides Hexapeptides Organofluorides Lactams Lactones Tertiary alcohols Heterocyclic compounds with 6 rings ...
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