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Cryptobiotic
Cryptobiosis or anabiosis is a metabolic state in extremophilic organisms in response to adverse environmental conditions such as desiccation, freezing, and oxygen Hypoxia (medical), deficiency. In the cryptobiotic state, all measurable metabolic processes stop, preventing reproduction, development, and repair. When environmental conditions return to being hospitable, the organism will return to its metabolism, metabolic state of life as it was prior to cryptobiosis. Forms Anhydrobiosis Anhydrobiosis is the most studied form of cryptobiosis and occurs in situations of extreme desiccation. The term ''anhydrobiosis'' derives from the Greek for "life without water" and is most commonly used for the desiccation tolerance observed in certain invertebrate animals such as Bdelloidea, bdelloid rotifers, tardigrades, brine shrimp, nematodes, and at least one insect, a species of chironomid (''Polypedilum vanderplanki''). However, other life forms exhibit desiccation tolerance. Thes ...
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Tardigrade Anhydrobiosis Cycle
Tardigrades (), known colloquially as water bears or moss piglets, are a phylum of eight-legged Segmentation (biology), segmented micro-animals. They were first described by the German zoologist Johann August Ephraim Goeze in 1773, who called them . In 1776, the Italian biologist Lazzaro Spallanzani named them Tardigrada, which means 'slow walkers'. They live in diverse regions of Earth's biospheremountaintops, the deep sea, tropical rainforests, and the Antarctic. Tardigrades are among the most resilient animals known, with individual species able to survive extreme conditions – such as exposure to extreme temperatures, extreme pressures (both high and low), air deprivation, radiation, dehydration, and starvation – that would quickly kill most other forms of life. Tardigrades have survived exposure to outer space. There are about 1,500 known species in the phylum Tardigrada, a part of the superphylum Ecdysozoa. The earliest known fossil is from the Cambrian, some 500 m ...
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Desiccation Tolerance
Desiccation tolerance refers to the ability of an organism to withstand or endure extreme dryness, or drought-like conditions. Plants and animals living in arid or periodically arid environments such as temporary streams or ponds may face the challenge of desiccation, therefore physiological or behavioral adaptations to withstand these periods are necessary to ensure survival. In particular, insects occupy a wide range of ecologically diverse niches and, so, exhibit a variety of strategies to avoid desiccation. In general, desiccation resistance in insects is measured by the change in mass during dry conditions. The overall mass difference between measurements before and after aridity exposure is attributed to body water loss, as respiratory water loss is generally considered negligible. Desiccation and plants Desiccation tolerant plants include ''Craterostigma plantagineum'', ''Lindernia brevidens'' and '' Ramonda serbica''. Desiccation sensitive plants include members of ''Ara ...
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Tardigrade
Tardigrades (), known colloquially as water bears or moss piglets, are a phylum of eight-legged segmented micro-animals. They were first described by the German zoologist Johann August Ephraim Goeze in 1773, who called them . In 1776, the Italian biologist Lazzaro Spallanzani named them Tardigrada, which means 'slow walkers'. They live in diverse regions of Earth's biospheremountaintops, the deep sea, tropical rainforests, and the Antarctic. Tardigrades are among the most resilient animals known, with individual species able to survive extreme conditions – such as exposure to extreme temperatures, extreme pressures (both high and low), air deprivation, radiation, dehydration, and starvation – that would quickly kill most other forms of life. Tardigrades have survived exposure to outer space. There are about 1,500 known species in the phylum Tardigrada, a part of the superphylum Ecdysozoa. The earliest known fossil is from the Cambrian, some 500 million years ago ...
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Nematode
The nematodes ( or ; ; ), roundworms or eelworms constitute the phylum Nematoda. Species in the phylum inhabit a broad range of environments. Most species are free-living, feeding on microorganisms, but many are parasitic. Parasitic worms (helminths) are the cause of soil-transmitted helminthiases. They are classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa. Unlike the flatworms, nematodes have a tubular digestive system, with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum. Nematode species can be difficult to distinguish from one another. Consequently, estimates of the number of nematode species are uncertain. A 2013 survey of animal biodiversity suggested there are over 25,000. Estimates of the total number of extant species are su ...
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Trehalose
Trehalose (from Turkish '' tıgala'' – a sugar derived from insect cocoons + -ose) is a sugar consisting of two molecules of glucose. It is also known as mycose or tremalose. Some bacteria, fungi, plants and invertebrate animals synthesize it as a source of energy, and to survive freezing and lack of water. Trehalose has high water retention capabilities, and is used in food, cosmetics and as a drug. Structure Trehalose is a disaccharide formed by a bond between two α-glucose units. It is found in nature as a disaccharide and also as a monomer in some polymers. Two other stereoisomers exist: α,β-trehalose, also called ''neotrehalose'', and β,β-trehalose, also called ''isotrehalose''. Neither of these alternate isomers has been isolated from living organisms, but isotrehalose has been was found in starch hydroisolates. Synthesis At least three biological pathways support trehalose biosynthesis. An industrial process can derive trehalose from corn starch. Properties ...
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Disaccharide
A disaccharide (also called a double sugar or ''biose'') is the sugar formed when two monosaccharides are joined by glycosidic linkage. Like monosaccharides, disaccharides are simple sugars soluble in water. Three common examples are sucrose, lactose, and maltose. Disaccharides are one of the four chemical groupings of carbohydrates (monosaccharides, disaccharides, oligosaccharides, and polysaccharides). The most common types of disaccharides—sucrose, lactose, and maltose—have 12 carbon atoms, with the general formula C12H22O11. The differences in these disaccharides are due to atomic arrangements within the molecule. The joining of monosaccharides into a double sugar happens by a condensation reaction, which involves the elimination of a water molecule from the functional groups only. Breaking apart a double sugar into its two monosaccharides is accomplished by hydrolysis with the help of a type of enzyme called a disaccharidase. As building the larger sugar ejects a ...
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Glucose
Glucose is a sugar with the Chemical formula#Molecular formula, molecular formula , which is often abbreviated as Glc. It is overall the most abundant monosaccharide, a subcategory of carbohydrates. It is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight. It is used by plants to make cellulose, the most abundant carbohydrate in the world, for use in cell walls, and by all living Organism, organisms to make adenosine triphosphate (ATP), which is used by the cell as energy. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as amylose and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar. The naturally occurring form is -glucose, while its Stereoisomerism, stereoisomer L-glucose, -glucose is produced synthetically in comparatively small amounts and is less biologicall ...
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Sucrose
Sucrose, a disaccharide, is a sugar composed of glucose and fructose subunits. It is produced naturally in plants and is the main constituent of white sugar. It has the molecular formula . For human consumption, sucrose is extracted and refined from either sugarcane or sugar beet. Sugar mills – typically located in tropical regions near where sugarcane is grown – crush the cane and produce raw sugar which is shipped to other factories for refining into pure sucrose. Sugar beet factories are located in temperate climates where the beet is grown, and process the beets directly into refined sugar. The Sugar refinery, sugar-refining process involves washing the raw sugar crystals before dissolving them into a sugar syrup which is filtered and then passed over carbon to remove any residual colour. The sugar syrup is then concentrated by boiling under a vacuum and crystallized as the final purification process to produce crystals of pure sucrose that are clear, odorless, and sweet. ...
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Intrinsically Disordered Proteins
In molecular biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered protein tertiary structure, three-dimensional structure, typically in the absence of its macromolecular interaction partners, such as other proteins or RNA. IDPs range from fully unstructured to partially structured and include random coil, molten globule-like Protein aggregation, aggregates, or flexible linkers in large multi-Protein domain, domain proteins. They are sometimes considered as a separate class of proteins along with globular protein, globular, fibrous protein, fibrous and membrane proteins. IDPs are a very large and functionally important class of proteins. They are most numerous in Eukaryote, eukaryotes, with an estimated 30-40% of residues in the eukaryotic proteome located in disordered regions. Disorder is present in around 70% of proteins, either in the form of disordered tails or flexible linkers. Proteins can also be entirely disordered and lack a define ...
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Bakers' Yeast
''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungal microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes. It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology, much like ''Escherichia coli'' as the model bacterium. It is the microorganism which causes many common types of fermentation. ''S. cerevisiae'' cells are round to ovoid, 5–10  μm in diameter. It reproduces by budding. Many proteins important in human biology were first discovered by studying their homologs in yeast; these proteins include cell cycle proteins, signaling proteins, and protein-processing enzymes. ''S. cerevisiae'' is currently the only yeast cell known to have Berkeley bodies present, which are involved in particular secretory pathways. Antibodies against ''S. cere ...
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Caenorhabditis Elegans
''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a Hybrid word, blend of the Greek ''caeno-'' (recent), ''rhabditis'' (rod-like) and Latin ''elegans'' (elegant). In 1900, Émile Maupas, Maupas initially named it ''Rhabditidae, Rhabditides elegans.'' Günther Osche, Osche placed it in the subgenus ''Caenorhabditis'' in 1952, and in 1955, Ellsworth Dougherty, Dougherty raised ''Caenorhabditis'' to the status of genus. ''C. elegans'' is an unsegmented pseudocoelomate and lacks respiratory or circulatory systems. Most of these nematodes are hermaphrodites and a few are males. Males have specialised tails for mating that include spicule (nematode), spicules. In 1963, Sydney Brenner proposed research into ''C. elegans,'' primarily in the area of neuronal development. In 1974, he began research into the molecular biology, molecular and developmental ...
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Dauer Larva
Dauer ( German "", English "the endurance", "persistence"; "unlimited time" ) describes an alternative developmental stage of nematode worms, particularly rhabditids including ''Caenorhabditis elegans'', whereby the larva goes into a type of stasis and can survive harsh conditions. Since the entrance of the dauer stage is dependent on environmental cues, it represents a classic and well studied example of polyphenism. The dauer state is given other names in the various types of nematodes such as ‘ diapause’ or ‘hypobiosis’, but since the ''C. elegans'' nematode has become the most studied nematode, the term ‘dauer stage’ or 'dauer larvae' is becoming universally recognised when referring to this state in other free-living nematodes. The dauer stage is also considered to be equivalent to the infective stage of parasitic nematode larvae. As Émile Maupas first proposed in 1899 and 1900, all nematodes have five stages separated by four moults. Under environmental condit ...
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