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Contaminated Haemophilia Blood Products
Contaminated hemophilia blood products were a serious public health problem in the late 1970s up to 1985. Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent or stop bleeding in people with hemophilia A. Contamination of these and other products caused large numbers of hemophiliacs to become infected with HIV and hepatitis C. The companies involved included Alpha Therapeutic Corporation, Institut Mérieux (which then became Rhone-Poulenc Rorer Inc., and is now part of Sanofi), Bayer Corporation and its Cutter Biological division, and Baxter International and its Hyland Pharmaceutical division. Estimates for HIV infections in the United States alone range from 6,000 to 10,000, with another 4,000 in France, 2,000 in Canada and 1,200 in the United Kingdom, and many more worldwide. Initial concerns In 1981 concern was growing over an unidentified infectious disease associated with im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemophilia A
Haemophilia A (or hemophilia A) is a blood clotting disorder caused by a genetic deficiency in clotting factor VIII, thereby resulting in significant susceptibility to bleeding, both internally and externally. This condition occurs almost exclusively in males born to carrier mothers due to X-linked recessive inheritance. Nevertheless, rare isolated cases do emerge from de novo (spontaneous) mutations. The medical management of individuals with hemophilia A frequently entails the administration of factor VIII medication through slow intravenous injection. This intervention aims to address and preempt additional bleeding episodes in affected individuals. Signs and symptoms Haemophilia A's phenotype has a quite wide range of symptoms encompassing both internal and external bleeding episodes. Individuals with more severe haemophilia tend to experience more intense and frequent bleeding, whereas those with mild haemophilia typically exhibit milder symptoms unless subjected to sur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Plasma
Blood plasma is a light Amber (color), amber-colored liquid component of blood in which blood cells are absent, but which contains Blood protein, proteins and other constituents of whole blood in Suspension (chemistry), suspension. It makes up about 55% of the body's total blood volume. It is the Intravascular compartment, intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (, , , , , etc.), hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and oxygen. It plays a vital role in an intravascular osmotic effect that keeps electrolyte concentration balanced and protects the body from infection and other blood-related disorders. Blood plasma can be separated from whole blood through blood fractionation, by adding an anticoagulant to a tube ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MSNBC
MSNBC is an American cable news channel owned by the NBCUniversal News Group division of NBCUniversal, a subsidiary of Comcast. Launched on July 15, 1996, and headquartered at 30 Rockefeller Plaza in Manhattan, the channel primarily broadcasts rolling news coverage and Modern liberalism in the United States, liberal-leaning Opinion journalism, political commentary. MSNBC was originally established as part of a joint venture between NBC News and Microsoft (with its name being a portmanteau of MSN and NBC), encompassing the channel and the news website NBCNews.com, MSNBC.com. Microsoft would divest its stake in the channel in 2005, followed by the website in 2012; the website was then rebranded as NBCNews.com to associate it more closely with the NBC News division, leaving MSNBC.com to become a website for the channel and its opinion content. MSNBC initially focused on rolling news coverage, including long-form reports, interactive television, interactive programs, and stories con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Citizen
Public Citizen is an American non-profit, Progressivism in the United States, progressive consumer rights advocacy group, and think tank based in Washington, D.C. It was founded in 1971 by the American activist and lawyer Ralph Nader. Lobbying efforts Public Citizen advocates before all three branches of the United States federal government. Its five divisions include Congress Watch; Energy; Global Trade Watch; the Health Research Group; and Public Citizen Litigation Group, a nationally prominent public interest law firm founded by Alan Morrison and known for its Supreme Court and appellate practice. Among other issues, Public Citizen has been a public voice on Prescription drug prices in the United States, drug pricing. For example, they advocated for Gilead Sciences to test GS-441524, a cheaper alternative to remdesivir. History In 1968, Nader recruited seven volunteer law students, dubbed "Nader's Raiders" by the Washington press corps, to evaluate the efficacy and operation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sidney M
Sidney may refer to: People * Sidney (surname), English surname * Sidney (given name), including a list of people with the given name * Sídney (footballer, born 1963) (Sídney José Tobias), Brazilian football forward * Sidney (footballer, born 1972) (Sidney da Silva Souza), Brazilian football defensive midfielder * Sidney (footballer, born 1979) (Sidney Santos de Brito), Brazilian football defender Fictional characters * Sidney Prescott, main character from the ''Scream'' horror trilogy * Sidney (''Ice Age''), a ground sloth in the ''Ice Age'' film series * Sidney, one of ''The Bash Street Kids'' * Sid Jenkins (Sidney Jenkins), a character in the British teen drama ''Skins'' * Sidney Hever, Edward's fireman from ''The Railway Series'' and the TV series ''Thomas and Friends''; see List of books in ''The Railway Series'' * Sidney, a diesel engine from the TV series; see List of ''Thomas & Friends'' characters * Sidney Freedman, a recurring character in the TV series ''M*A*S*H' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hong Kong
Hong Kong)., Legally Hong Kong, China in international treaties and organizations. is a special administrative region of China. With 7.5 million residents in a territory, Hong Kong is the fourth most densely populated region in the world. Hong Kong was established as a colony of the British Empire after the Qing dynasty ceded Hong Kong Island in 1841–1842 as a consequence of losing the First Opium War. The colony expanded to the Kowloon Peninsula in 1860 and was further extended when the United Kingdom obtained a 99-year lease of the New Territories in 1898. Hong Kong was occupied by Japan from 1941 to 1945 during World War II. The territory was handed over from the United Kingdom to China in 1997. Hong Kong maintains separate governing and economic systems from that of mainland China under the principle of one country, two systems. Originally a sparsely populated area of farming and fishing villages,. the territory is now one of the world's most signific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taiwan
Taiwan, officially the Republic of China (ROC), is a country in East Asia. The main geography of Taiwan, island of Taiwan, also known as ''Formosa'', lies between the East China Sea, East and South China Seas in the northwestern Pacific Ocean, with the China, People's Republic of China (PRC) to the northwest, Japan to the northeast, and the Philippines to the south. It has an area of , with mountain ranges dominating the eastern two-thirds and plains in the western third, where its Urbanization by country, highly urbanized population is concentrated. The combined Free area of the Republic of China, territories under ROC control consist of list of islands of Taiwan, 168 islands in total covering . The Taipei–Keelung metropolitan area, largest metropolitan area is formed by Taipei (the capital), New Taipei City, and Keelung. With around 23.9 million inhabitants, Taiwan is among the List of countries and dependencies by population density, most densely populated countries. Tai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fixed-price Contract
A fixed-price contract is a type of contract for the supply of goods or services, such that the agreed payment amount will not subsequently be adjusted to reflect the resources used, costs incurred or time expended by the contractor. This contract type may be contrasted with a cost-plus contract, which is intended to cover the costs incurred by the contractor plus an additional amount for profit, and with time-and-materials contracts and labor-hour contracts.General Services AdministrationFederal Acquisition Regulation Subpart 16.2 - Fixed-Price Contracts effective 12 April 2023, accessed 16 January 2024 Fixed-price contracts are one of the main options available when contracting for supplies to governments. Fixed prices can require more time, in advance, for sellers to determine the price of each item. However, the fixed-price items can each be purchased faster, but bargaining could set the price for an entire set of items being purchased, reducing the time for bulk purchases. Al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Underdeveloped Countries
The least developed countries (LDCs) are developing countries listed by the United Nations that exhibit the lowest indicators of socioeconomic development. The concept of LDCs originated in the late 1960s and the first group of LDCs was listed by the UN in its resolution 2768 (XXVI) on 18 November 1971. A country is classified among the Least Developed Countries if it meets three criteria:UN-OHRLLS . * Poverty – adjustable criterion based on Gross national income (GNI) per capita averaged over three years. , a country must have GNI per capita less than US$1,025 to be included on the list, and over $1,230 to graduate from it. * Human resource weakness (based on indicators of nutrition, health, education and adult literacy). * Economic vulnerability (based on instability of agricultural production, instability of exports of goods and services, economic importance of non-traditional activities, merchandise export concentration, handicap of economic smallness, and the percenta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prison
A prison, also known as a jail, gaol, penitentiary, detention center, correction center, correctional facility, or remand center, is a facility where Prisoner, people are Imprisonment, imprisoned under the authority of the State (polity), state, usually as punishment for various crimes. They may also be used to house those awaiting trial (pre-trial detention). Prisons are most commonly used within a criminal justice, criminal-justice system by authorities: people charged with crimes may be Remand (detention), imprisoned until their trial; and those who have pleaded or been found Guilt (law), guilty of crimes at trial may be Sentence (law), sentenced to a specified period of imprisonment. Prisons can also be used as a tool for political repression by authoritarianism, authoritarian regimes who Political prisoner, detain perceived opponents for political crimes, often without a fair trial or due process; this use is illegal under most forms of international law governing fair admi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
