Colour Dilution Alopecia
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Colour Dilution Alopecia
Follicular dysplasia is a genetic disease of dogs causing alopecia, also called hair loss. It is caused by hair follicles that are misfunctioning due to structural abnormality. There are several types, some affecting only certain breeds. Diagnosis is achieved through a biopsy, and treatment is rarely successful. Certain breeds, such as the Mexican Hairless Dog and Chinese Crested Dog, are bred specifically for alopecia. Structural follicular dysplasia Structural follicular dysplasia varies by breed but all involve weakened hairs that break easily. Hair loss is originally seen in areas of repeated grooming or trauma, for instance the neck because of contact with a collar. Hair regrowth may occur, but the hair will be even weaker and the pattern will repeat. The dogs are affected between the ages of two and four years, and it is most commonly seen on the back towards the tail. Progression of the hair loss to cover the trunk can occur. Commonly affected breeds *Irish Water Spaniel * ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (bi ...
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Airedale Terrier
The Airedale Terrier (often shortened to "Airedale"), also called Bingley Terrier and Waterside Terrier, is a dog breed of the terrier type that originated in the valley (''dale'') of the River Aire, in the West Riding of Yorkshire, England. It is traditionally called the "King of Terriers" because it is the largest of the terrier breeds. The Airedale was bred from the Old English Black and Tan Terrier and the Otterhound and probably some other Terrier breeds, and has contributed to other dog breeds, such as the Yorkshire Terrier. Originally bred to serve as a versatile hunting and all around working farm dog, this breed has also been used as a war dog, guide dog, and police dog in Britain. In the United States, the breed has been used to hunt big game, upland birds, and water fowl, and serve in many other working capacities. Description Appearance Airedale Terriers being judged at a dog show. The Airedale is the largest of the British terriers. They weigh in fit condi ...
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Melanin
Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melanocytes. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin, allomelanin and pyomelanin. Melanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. Pheomelanin is a cysteinated form containing poly benzothiazine portions that are largely responsible for the red or yellow tint given to some skin or hair colors. Neuromelanin is found in the brain. Research has been undertaken to investigate its efficacy in treating neurodegenerative disorders such as Parkinson's. Allomelanin and pyomelanin are two types of nitrogen-free melanin. The phenotypic color variation observed in the epidermis and hair of mammals is primarily determi ...
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Coat (dog)
The coat of the domestic dog refers to the hair that covers its body. Dogs demonstrate a wide range of coat colors, patterns, textures, and lengths. As with other mammals, a dog's fur has many uses, including thermoregulation and protection from cuts or scratches; furthermore, a dog's coat plays an important role in the Conformation show, showing of purebred dogs. Breed standards often include a detailed description of the nature and attributes of that breed's ideal coat. A dog's coat is composed of two layers: a top coat of stiff guard hairs that help repel water and shield from dirt, and an undercoat of soft down hairs, to serve as insulation. Dogs with both under coat and top coat are said to have a ''double coat''. Dogs with a ''single coat'' have a coat composed solely of guard hairs, with little or no downy undercoat. The terms fur and hair are often used interchangeably when describing a dog's coat, however in general, a double coat, like that of the Newfoundland (dog), ...
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Eumelanin
Melanin (; ) is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. Melanin pigments are produced in a specialized group of cells known as melanocytes. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin, allomelanin and pyomelanin. Melanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. Pheomelanin is a cysteinated form containing poly benzothiazine portions that are largely responsible for the red or yellow tint given to some skin or hair colors. Neuromelanin is found in the brain. Research has been undertaken to investigate its efficacy in treating neurodegenerative disorders such as Parkinson's. Allomelanin and pyomelanin are two types of nitrogen-free melanin. The phenotypic color variation observed in the epidermis and hair of mammals is primarily determine ...
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Dilution Gene
A dilution gene is any one of a number of genes that act to create a lighter coat color in living creatures. There are many examples of such genes: General Diluted coat colors have melanocytes, but vary from darker colors due to the concentration or type of these pigment-producing cells, not their absence. Pigment dilution, sometimes referred to as hypomelanism, has been called leucism, albinism (perfect, impartial, or dilute), ghosting, paling, and isabellinism. *Albinism describes a condition where pigment cells synthesize little or no pigment *Leucism describes a condition that creates loss of pigment cells Cats Cat coat genetics discusses many dilution genes in cats. Dogs In dogs, a mutation of the ''MLPH'' locus known as the dilute gene causes eumelanin to lighten while pheomelanin remains almost unchanged. Dogs of some breeds with the dilute gene often suffer from colour dilution alopecia (CDA). Appearance Of the colour shades found in the coat of dogs, the light brown ...
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Color Dilution Alopecia 2
Color (or colour in English in the Commonwealth of Nations, Commonwealth English; American and British English spelling differences#-our, -or, see spelling differences) is the visual perception based on the electromagnetic spectrum. Though color is not an inherent property of matter, color perception is related to an object's light absorption, emission spectra, emission, Reflection (physics), reflection and Transmittance, transmission. For most humans, colors are perceived in the visible light spectrum with three types of cone cells (trichromacy). Other animals may have a different number of cone cell types or have eyes sensitive to different wavelengths, such as bees that can distinguish ultraviolet, and thus have a different color sensitivity range. Animal perception of color originates from different light wavelength or spectral sensitivity in cone cell types, which is then processed by the brain. Colors have perceived properties such as hue, colorfulness (saturation), and ...
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Lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing energy, signaling, and acting as structural components of cell membranes. Lipids have applications in the cosmetic and food industries, and in nanotechnology. Lipids are broadly defined as hydrophobic or amphiphilic small molecules; the amphiphilic nature of some lipids allows them to form structures such as vesicles, multilamellar/ unilamellar liposomes, or membranes in an aqueous environment. Biological lipids originate entirely or in part from two distinct types of biochemical subunits or "building-blocks": ketoacyl and isoprene groups. Using this approach, lipids may be divided into eight categories: fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, saccharolipids, and polyketides (derived from condensatio ...
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Rottweiler
The Rottweiler (, , ) is a breed of domestic dog, regarded as medium-to-large or large. The dogs were known in German as , meaning Rottweil butchers' dogs, because their main use was to herd livestock and pull carts laden with butchered meat to market. This continued until the mid-19th century when railways replaced droving. Although still used to herd stock in many parts of the world, Rottweilers are now also used as search and rescue dogs, guard dogs, and police dogs.Adolf Pienkoss, ''The Rottweiler'', 3rd ed., Borken, Germany: Internationale Föderation der Rottweilerfreunde, 2008. History According to the FCI Standard, the Rottweiler is considered to be one of the oldest surviving dog breeds. Its origin goes back to Roman times. These dogs were kept as herder or driving dogs. They marched over the Alps with the Roman legions, protecting the humans and driving their cattle. In the region of Rottweil, these dogs met and mixed with the native dogs in a natural crossing. ...
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Affenpinscher
The Affenpinscher () is a German list of dog breeds, breed of small toy dog of Pinscher type. Originally developed as a Ratter (dog), mouser, the Affenpinscher is now commonly found as a Companion dog, companion worldwide. History The word '' derives from , German for 'ape' or 'monkey'; it is sometimes translated as 'Monkey Terrier', although the dog is a pinscher and not a terrier. The origins of the Pinscher group of dogs are unknown. Dogs of this type, both rough-haired and smooth-haired, were traditionally kept as carriage dogs or as stable dogs, and so were sometimes known as ; they were capable ratter (dog), ratters. Until the late nineteenth century, both rough-haired and smooth-haired types were known as Deutscher Pinscher, and came from the same lineage; puppies of both types could occur in the same litter. In 1880 the Pinscher was recorded in the ''Deutschen Hundestammbuch'' of the Verein zur Veredelung der Hunderassen. In 1895 described five varieties of Pinscher ...
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Boxer (dog)
The Boxer is a medium to large, short-haired dog breed of mastiff-type, developed in Germany. The coat is smooth and tight-fitting; colors are Fawn (colour), fawn or brindled, with or without white markings. Boxers are Cephalic index#Brachycephalic animals, brachycephalic (they have broad, short skulls), have a square muzzle, mandible, mandibular prognathism (an underbite), very strong jaws, and a powerful bite ideal for hanging on to large prey. The Boxer was bred from the Old English Bulldog and the now extinct Bullenbeisser, which became extinct by crossbreeding rather than by a decadence of the breed. The Boxer is a member of both The Kennel Club and American Kennel Club (AKC) Working Group.http://www.akc.org/dog-breeds/boxer/#standard "Get to Know the Boxer", 'The American Kennel Club', Retrieved 14 May 2014 The first Boxer club was founded in 1895, with Boxers being first exhibited in a dog show for St. Bernard (dog), St. Bernards in Munich the next year. Based on 2013 AKC st ...
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Wirehaired Pointing Griffon
The Wirehaired Pointing Griffon (also called the Korthals Griffon and the Griffon d'arrêt à poil dur Korthals in France and Quebec) is a breed of dog used in hunting as a gundog. It is sometimes considered to be Dutch in ancestry, due to the nationality of the breed founder, Eduard Karel Korthals. History records the progression of the development of the breed through Biebesheim am Rhein, Germany where the founder established the Ipenwoud kennel and the breed type was established and then into France where it is now recognized. Others consider the Griffon to be a German breed because Korthals' kennel, Ipenwoud, was located in Biebesheim am Rhein, Germany. It was there for over twenty years that Korthals dedicated his life to the development and perfection of the Korthals Griffon. The breed is still relatively rare in the United States, Canada, and the United Kingdom despite long recognition by their respective national kennel clubs, as well as the FCI (Federation C ...
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