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Cochlear Implant
A cochlear implant (CI) is a surgically implanted Neuroprosthetics, neuroprosthesis that provides a person who has moderate-to-profound sensorineural hearing loss with sound perception. With the help of therapy, cochlear implants may allow for improved speech understanding in both quiet and noisy environments. A CI bypasses acoustic hearing by direct electrical stimulation of the auditory nerve. Through everyday listening and auditory training, cochlear implants allow both children and adults to learn to interpret those signals as speech and sound. The implant has two main components. The outside component is generally worn behind the ear, but could also be attached to clothing, for example, in young children. This component, the sound processor, contains microphones, electronics that include digital signal processor (DSP) chips, battery, and a coil that transmits a signal to the implant across the skin. The inside component, the actual implant, has a coil to receive signals, elect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroprosthetics
Neuroprosthetics (also called neural prosthetics) is a discipline related to neuroscience and biomedical engineering concerned with developing neural prostheses. They are sometimes contrasted with a brain–computer interface, which connects the brain to a computer rather than a device meant to replace missing biological functionality. Neural prostheses are a series of devices that can substitute a motor, sensory or cognitive modality that might have been damaged as a result of an injury or a disease. Cochlear implants provide an example of such devices. These devices substitute the functions performed by the eardrum and stapes while simulating the frequency analysis performed in the cochlea. A microphone on an external unit gathers the sound and processes it; the processed signal is then transferred to an implanted unit that stimulates the auditory nerve through a microelectrode array. Through the replacement or augmentation of damaged senses, these devices are intended to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert L
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' () "fame, glory, honour, praise, renown, godlike" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin.Reaney & Wilson, 1997. ''Dictionary of English Surnames''. Oxford University Press. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe, the name entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including En ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glutamic Acid
Glutamic acid (symbol Glu or E; known as glutamate in its anionic form) is an α- amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can synthesize enough for its use. It is also the most abundant excitatory neurotransmitter in the vertebrate nervous system. It serves as the precursor for the synthesis of the inhibitory gamma-aminobutyric acid (GABA) in GABAergic neurons. Its molecular formula is . Glutamic acid exists in two optically isomeric forms; the dextrorotatory -form is usually obtained by hydrolysis of gluten or from the waste waters of beet-sugar manufacture or by fermentation.Webster's Third New International Dictionary of the English Language Unabridged, Third Edition, 1971. Its molecular structure could be idealized as HOOC−CH()−()2−COOH, with two carboxyl groups −COOH and one amino group −. However, in the solid state and mildly acidic water s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotransmitter
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a Chemical synapse, synapse. The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. Some neurotransmitters are also stored in large dense core vesicles. The neurotransmitter's effect on the target cell is determined by the receptor it binds to. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available and often require a small number of biosynthetic steps for conversion. Neurotransmitters are essential to the function of complex neural systems. The exact number of unique neurotransmitters in humans is unknown, but more than 100 have been identified. Common neurotransmitters include Glutamate (neurotransmi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Potassium
Potassium is a chemical element; it has Symbol (chemistry), symbol K (from Neo-Latin ) and atomic number19. It is a silvery white metal that is soft enough to easily cut with a knife. Potassium metal reacts rapidly with atmospheric oxygen to form flaky white potassium peroxide in only seconds of exposure. It was first isolated from potash, the ashes of plants, from which its name derives. In the periodic table, potassium is one of the alkali metals, all of which have a single valence electron in the outer electron shell, which is easily removed to create cation, an ion with a positive charge (which combines with anions to form salts). In nature, potassium occurs only in ionic salts. Elemental potassium reacts vigorously with water, generating sufficient heat to ignite hydrogen emitted in the reaction, and burning with a lilac-flame color, colored flame. It is found dissolved in seawater (which is 0.04% potassium by weight), and occurs in many minerals such as orthoclase, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stereocilia (inner Ear)
In the inner ear, stereocilia are the mechanosensing organelles of hair cells, which respond to fluid motion in numerous types of animals for various functions, including hearing and balance. They are about 10–50 micrometers in length and share some similar features of microvilli.Caceci, T. VM8054 Veterinary Histology: Male Reproductive System. http://education.vetmed.vt.edu/Curriculum/VM8054/Labs/Lab27/Lab27.htm (accessed 2/16/06). The hair cells turn the fluid pressure and other mechanical stimuli into electric stimuli via the many microvilli that make up stereocilia rods.Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. (2002) The Molecular Biology of the Cell. Garland Science Textbooks. Stereocilia exist in the Auditory system, auditory and Vestibular system, vestibular systems. Morphology Resembling hair-like projections, the stereocilia are arranged in bundles of 30–300. Within the bundles the stereocilia are often lined up in several rows of i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hair Cells
Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates, and in the lateral line organ of fishes. Through mechanotransduction, hair cells detect movement in their environment. In mammals, the auditory hair cells are located within the spiral organ of Corti on the thin basilar membrane in the cochlea of the inner ear. They derive their name from the tufts of stereocilia called ''hair bundles'' that protrude from the apical surface of the cell into the fluid-filled cochlear duct. The stereocilia number from fifty to a hundred in each cell while being tightly packed together and decrease in size the further away they are located from the kinocilium. Mammalian cochlear hair cells are of two anatomically and functionally distinct types, known as outer, and inner hair cells. Damage to these hair cells results in decreased hearing sensitivity, and because the inner ear hair cells cannot regenerate, this dam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Auditory System
The auditory system is the sensory system for the sense of hearing. It includes both the ear, sensory organs (the ears) and the auditory parts of the sensory system. System overview The outer ear funnels sound vibrations to the eardrum, increasing the sound pressure in the middle frequency range. The Middle ear, middle-ear ossicles further amplify the vibration pressure roughly 20 times. The base of the stapes couples vibrations into the cochlea via the oval window, which vibrates the perilymph liquid (present throughout the inner ear) and causes the round window to bulb out as the oval window bulges in. Vestibular duct, Vestibular and tympanic ducts are filled with perilymph, and the smaller cochlear duct between them is filled with endolymph, a fluid with a very different ion concentration and voltage. Vestibular duct perilymph vibrations bend organ of Corti outer cells (4 lines) causing prestin to be released in cell tips. This causes the cells to be chemically elongated an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erwin Hochmair
Erwin Hochmair (born 1940) is an Austrian electrical engineer whose research focuses in the fields of biomedical engineering and cochlear implant design. He has been a professor at the Institute of Experimental Physics, University of Innsbruck since 1986. He has authored and co-authored over 100 technical articles and holds about 50 patents. He is the co-founder and owner of the medical device company MED-EL. Biography Hochmair was born in Vienna in 1940. He received his Dipl.-Ing. and D.Tech. degrees in electrical engineering from the Technical University of Vienna in 1964 and 1967, respectively. He joined the Institute for Physical Electronics of the Technical University of Vienna in 1965, where he taught courses on linear integrated circuits and circuit design. He worked as a research associate at Marshall Space Flight Center, in the U.S. from 1970 to 1972 where he designed analog integrated circuits in CMOS technology. He was a visiting associate professor at Stanford U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ingeborg Hochmair
Ingeborg J. Hochmair-Desoyer (born 1953) is an Austrian electrical engineer and the CEO and CTO of hearing implant company MED-EL. Dr Hochmair and her husband Prof. Erwin Hochmair co-created the first micro-electronic multi-channel cochlear implant in the world. She received the Lasker-DeBakey Clinical Medical Research Award for her contributions towards the development of the modern cochlear implant. She also received the 2015 Russ Prize for bioengineering. In 1989, she co-founded the medical device company MED-EL. Biography Ingeborg Hochmair was born in 1953 in Vienna, Austria. Her mother was a physicist and her father was dean of the faculty of mechanical engineering at Vienna University of Technology. Her grandmother was one of the first female chemical engineers in Austria. She commenced her studies at Technical University of Vienna in electrical engineering in 1971, and in 1975, she became the first woman in Austria to receive a PhD in electrical engineering. Her disser ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graeme Clark (doctor)
Graeme Milbourne Clark (born 16 August 1935) is an Australian Professor of Otolaryngology at the University of Melbourne. He has worked in ENT surgery, electronics and speech science, and contributed towards the development of the multiple-channel cochlear implant. His invention was later marketed by Cochlear Limited. Early life and education Clark was born in Camden, New South Wales, to parents Colin and Dorothy Clark. He has one younger sister. Clark was educated at Carey Baptist Grammar School, where he was later honoured with the 'Carey Medal' in 1997. Clark was educated at The Scots College and studied medicine at Sydney University. He specialized in ear, nose and throat surgery at the Royal National Throat, Nose and Ear Hospital and obtained a fellowship in 1964 from the Royal College of Surgeons, London. Clark returned to Australia where he became a Fellow of the Royal Australian College of Surgeons and in 1969 completed his PhD at the University of Sydney on "Mid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Aeronautics And Space Administration
The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the United States's civil space program, aeronautics research and space research. Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the American space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo program missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station (ISS) along with the Commercial Crew Program and oversees the development of the Orion spacecraft and the Space Launch System for the lunar Artemis program. NASA's science division is focused on better understanding Earth through the Earth Observing System; advancing heliophysics through the effor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
