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Cluster 5
Cluster 5 is a designation used by the Danish Statens Serum Institut for a virus variant described by the institute in autumn 2020, in connection with investigations of SARS-CoV-2 infection among mink and humans in the north of Jutland, Denmark. On 3 November 2020, the institute delivered a risk assessment, in which a preliminary experiment with this virus variant described on one and a half pages, was the basis for an assessment concerning the efficacy of future COVID-19 vaccines. With reference to this risk assessment, the Danish government on 4 November 2020 mandated the killing all the country's mink. and a lockdown with tightened restrictions was introduced in seven North Jutland municipalities. At the time the decision to kill all Danish mink was made, the virus variant had last been detected on 15 September 2020. After subsequent testing and sequencing of positive samples in the seven North Jutland municipalities, the date of the latest finding was still 15 September 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statens Serum Institut
Statens Serum Institut (SSI, The State's Serum Institute), is a Danish sector research institute located on the island of Amager in Copenhagen. Its purpose is to combat and prevent infectious diseases, congenital disorders, and threats from weapons of mass destruction. History Founded in 1902 in the barracks of the Artillerivej road, it has now expanded to much more than its original size and is now one of Denmark's largest research institutions in the health sector. 20% of sales are used on Research and Development and Danish and International funds contribute around 100 million DKK. Administratively, the State Serum Institute sorts under the Danish Ministry of Health and Prevention under minister of health. Virologist Herdis von Magnus headed the institute's enterovirus department in 1955 and led the development and distribution of the polio vaccine in Denmark. The president and CEO of the institute has since 2020 been Henrik Ullum, preceded by Kåre Mølbak. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronavirus Disease 2019
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever, fatigue, cough, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms ( dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms ( respiratory failure, shock, or multiorgan dysfunction). Older people have a higher risk of developing severe symptoms. Some complications result in death. Some people continue to experience a range of effects ( long COVID) for mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histidine
Histidine (symbol His or H) is an essential amino acid that is used in the biosynthesis of proteins. It contains an Amine, α-amino group (which is in the protonated –NH3+ form under Physiological condition, biological conditions), a carboxylic acid group (which is in the deprotonated –COO− form under biological conditions), and an imidazole side chain (which is partially protonated), classifying it as a positively charged amino acid at physiological pH. Initially thought essential amino acid, essential only for infants, it has now been shown in longer-term studies to be essential for adults also. It is Genetic code, encoded by the Genetic code, codons CAU and CAC. Histidine was first isolated by Albrecht Kossel and Sven Gustaf Hedin in 1896. The name stems from its discovery in tissue, from ''histós'' "tissue". It is also a Precursor (chemistry), precursor to histamine, a vital inflammatory agent in immune responses. The acyl radical (chemistry), radical is histidyl. Pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronavirus Spike Protein
Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion. The distinctive appearance of these spikes when visualized using negative stain transmission electron microscopy, "recalling the solar corona", gives the virus family its main name. The function of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing the viral and cellular membranes. Spike glycoprotein is a class I fusion protein that contains two regions, known as S1 and S2, responsible for these two functions. The S1 region contains the receptor-binding domain that binds to receptors on the cell surface. Coronaviruses use a very diverse range of receptors; HCoV-NL63, SARS-CoV ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Cluster
A gene cluster is a group of two or more genes found within an organism's DNA that encode similar peptide, polypeptides or proteins which collectively share a generalized function and are often located within a few thousand base pairs of each other. The size of gene clusters can vary significantly, from a few genes to several hundred genes. Portions of the DNA sequence of each gene within a gene cluster are found to be identical; however, the protein encoded by each gene is distinct from the proteins encoded by the other genes within the cluster. Gene clusters often result from expansions of a single gene caused by repeated duplication events, and may be observed near one another on the same chromosome or on different, but homologous chromosomes. An example of a gene cluster is the Hox gene, which is made up of eight genes and is part of the Homeobox gene family. Formation Historically, four models have been proposed for the formation and persistence of gene clusters. Gene dupli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Jerusalem Post
''The Jerusalem Post'' is an English language, English-language Israeli broadsheet newspaper based in Jerusalem, Israel, founded in 1932 during the Mandate for Palestine, British Mandate of Mandatory Palestine, Palestine by Gershon Agron as ''The Palestine Post''. In 1950, it changed its name to ''The Jerusalem Post''. In 2004, the paper was bought by Mirkaei Tikshoret, a diversified Israeli media firm controlled by investor Eli Azur (who in 2014 also acquired the newspaper ''Maariv (newspaper), Maariv''). ''The Jerusalem Post'' is published in English. Previously, it also had a French edition. The paper describes itself as being in the Politics of Israel, Israeli political political center, center, which is considered to be Centre-right politics, center-right by Far-right politics in Israel, international standards; its editorial line is critical of political corruption, and supportive of the separation of religion and state in Israel. It is also a strong proponent of greater in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Times Of Israel
''The Times of Israel'' (ToI) is an Israeli multi-language online newspaper that was launched in 2012 and has since become the largest English-language Jewish and Israeli news source by audience size. It was co-founded by Israeli journalist David Horovitz, who is also the founding editor, and American billionaire investor Seth Klarman.Forbes: The World's Billionaires: Seth Klarman . April 2014. Based in , it "documents developments in Israel, the Middle East and around the Jewish world." Along with its original English site, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oregon
Oregon ( , ) is a U.S. state, state in the Pacific Northwest region of the United States. It is a part of the Western U.S., with the Columbia River delineating much of Oregon's northern boundary with Washington (state), Washington, while the Snake River delineates much of its eastern boundary with Idaho. The 42nd parallel north, 42° north parallel delineates the southern boundary with California and Nevada. The western boundary is formed by the Pacific Ocean. Oregon has been home to many Indigenous peoples of the Americas, indigenous nations for thousands of years. The first European traders, explorers, and settlers began exploring what is now Oregon's Pacific coast in the early to mid-16th century. As early as 1564, the Spanish expeditions to the Pacific Northwest, Spanish began sending vessels northeast from the Philippines, riding the Kuroshio Current in a sweeping circular route across the northern part of the Pacific. In 1592, Juan de Fuca undertook detailed mapping a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wisconsin
Wisconsin ( ) is a U.S. state, state in the Great Lakes region, Great Lakes region of the Upper Midwest of the United States. It borders Minnesota to the west, Iowa to the southwest, Illinois to the south, Lake Michigan to the east, Michigan to the northeast, and Lake Superior to the north. With a population of about 6 million and an area of about 65,500 square miles, Wisconsin is the List of U.S. states and territories by population, 20th-largest state by population and the List of U.S. states and territories by area, 23rd-largest by area. It has List of counties in Wisconsin, 72 counties. Its List of municipalities in Wisconsin by population, most populous city is Milwaukee; its List of capitals in the United States, capital and second-most populous city is Madison, Wisconsin, Madison. Other urban areas include Green Bay, Wisconsin, Green Bay, Kenosha, Wisconsin, Kenosha, Racine, Wisconsin, Racine, Eau Claire, Wisconsin, Eau Claire, and the Fox Cities. Geography of Wiscon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michigan
Michigan ( ) is a peninsular U.S. state, state in the Great Lakes region, Great Lakes region of the Upper Midwest, Upper Midwestern United States. It shares water and land boundaries with Minnesota to the northwest, Wisconsin to the west, Indiana and Illinois to the southwest, Ohio to the southeast, and the Canadian Provinces and territories of Canada, province of Ontario to the east, northeast and north. With a population of 10.14 million and an area of , Michigan is the List of U.S. states and territories by population, 10th-largest state by population, the List of U.S. states and territories by area, 11th-largest by area, and the largest by total area east of the Mississippi River.''i.e.'', including water that is part of state territory. Georgia (U.S. state), Georgia is the largest state by land area alone east of the Mississippi and Michigan the second-largest. The state capital is Lansing, Michigan, Lansing, while its most populous city is Detroit. The Metro Detroit r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Utah
Utah is a landlocked state in the Mountain states, Mountain West subregion of the Western United States. It is one of the Four Corners states, sharing a border with Arizona, Colorado, and New Mexico. It also borders Wyoming to the northeast, Idaho to the north, and Nevada to the west. In comparison to all the U.S. states and territories, Utah, with a population of just over three million, is the List of U.S. states and territories by area, 13th largest by area, the List of U.S. states and territories by population, 30th most populous, and the List of U.S. states by population density, 11th least densely populated. Urban development is mostly concentrated in two regions: the Wasatch Front in the north-central part of the state, which includes the state capital, Salt Lake City, and is home to roughly two-thirds of the population; and Washington County, Utah, Washington County in the southwest, which has approximately 180,000 residents. Most of the western half of Utah lies in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Department Of Agriculture
The United States Department of Agriculture (USDA) is an executive department of the United States federal government that aims to meet the needs of commercial farming and livestock food production, promotes agricultural trade and production, works to assure food safety, protects natural resources, fosters rural communities and works to end hunger in the United States and internationally. It is headed by the secretary of agriculture, who reports directly to the president of the United States and is a member of the president's Cabinet. The current secretary is Brooke Rollins, who has served since February 13, 2025. Approximately 71% of the USDA's $213 billion budget goes towards nutrition assistance programs administered by the Food and Nutrition Service (FNS). The largest component of the FNS budget is the Supplemental Nutrition Assistance Program (formerly known as the 'Food Stamp' program), which is the cornerstone of USDA's nutrition assistance. The United Stat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
