Chlorsulfuron
Chlorsulfuron is an Acetolactate synthase inhibitor, ALS (acetolactate synthase) inhibitor herbicide, and is a sulfonylurea compound. It was discovered by George Levitt in February 1976 while working at E. I. du Pont de Nemours and Company, DuPont, which was the patent assignee. Brand names Originally introduced in 1982 under the brand name Glean by DuPont, later also as Telar, in North America. Chemistry The first synthesis of chlorsulfuron was disclosed in a patent filed by the American chemical company DuPont (1802–2017), DuPont in 1977. 2-Chlorobenzenesulfonyl isocyanate was condensation reaction, condensed with 2-amino-4-methoxy-6-methyl-1,3,5-triazine to form the sulfonylurea product. : Mode of action Chlorsulfuron is an herbicide of the acetolactate synthase inhibitor (ALS inhibitor) class, Herbicide Resistance Action Committee, HRAC (Herbicide Resistance Action Committee) group 2 (legacy HRAC Group B, Australian Group B). Efficacy ''Triticum aestivum'' is naturally ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sulfonylurea
Sulfonylureas or sulphonylureas are a class of organic compounds used in medicine and agriculture. The functional group consists of a sulfonyl group (-S(=O)2) with its sulphur atom bonded to a nitrogen atom of a ureylene group (N,N-dehydrourea, a dehydrogenated derivative of urea). The side chains R1 and R2 distinguish various sulfonylureas. Sulfonylureas are the most widely used herbicide. Agricultural uses Many sulfonylureas are also used as herbicides, because they can interfere with plant biosynthesis of certain amino acids. As herbicides sulfonylureas function by interfering with biosynthesis of the amino acids valine, isoleucine, and leucine, specifically via acetolactate synthase inhibition. Compounds in this class include amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, chlorsulfuron, ethametsulfuron-methyl, cinosulfuron, ethoxysulfuron, flazasulfuron, flupyrsulfuron-methyl-sodium, imazosulfuron, metsulfuron-methyl, nicosulfuron, oxasulfuro ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Acetolactate Synthase Inhibitor
The acetolactate synthase (ALS) enzyme (also known as acetohydroxy acid or acetohydroxyacid synthase, abbr. AHAS) is a protein found in plants and micro-organisms. ALS catalyzes the first step in the synthesis of the branched-chain amino acids (valine, leucine, and isoleucine). A human protein of yet unknown function, sharing some sequence similarity with bacterial ALS, is encoded by the ILVBL (ilvB-like) gene. Structure Gene Human ILVBL gene has 17 exons resides on chromosome 19 at q13.1. Protein The catalytic peptide of ALS in ''Arabidopsis thaliana'' (mouse-eared cress) is a chloroplastic protein consisting of 670 residues, the last 615 of which form the active form. Three main domains are found, with two thiamine pyrophosphate sandwiching a DHS-like NAD/FAD-binding domain. In SCOP assignment, these subunits are named d1yhya1, d1yhya2, and d1yhya3 from the N-terminal to the C-terminal. The structure of acetolactate synthase that was used for the picture on this page was d ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Selectable Marker
A selectable marker is a gene introduced into cell (biology), cells, especially bacteria or cells in cell culture, culture, which confers one or more traits suitable for artificial selection. They are a type of reporter gene used in laboratory microbiology, molecular biology, and genetic engineering to indicate the success of a transfection or genetic transformation, transformation or other procedure meant to introduce foreign DNA into a cell. Selectable markers are often antibiotic resistance genes: bacteria subjected to a procedure by which exogenous DNA containing an antibiotic resistance gene (usually alongside other genes of interest) has been introduced are grown on a medium containing an antibiotic, such that only those bacterial cells which have successfully taken up and gene expression, expressed the introduced genetic material, including the gene which confers antibiotic resistance, can survive and produce colony (biology), colonies. The genes encoding resistance to antibio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pendimethalin
Pendimethalin is an herbicide of the dinitroaniline class p.328 used premergently and postemergently to control annual grasses and certain broadleaf weeds. It inhibits cell division and cell elongation. Pendimethalin is a K1-group (in Australia group D, or numerically group 3) according to the Herbicide Resistance Action Committee (HRAC) classification and is approved in Europe, North America, South America, Africa, Asia and Oceania for different crops including cereals (wheat, barley, rye, triticale), corn, soybeans, rice, potato, legumes, fruits, vegetables, and nuts, plus lawns and ornamental plants. Use Pendimethalin protects crops like wheat, corn, soybeans, potatoes, cabbage, peas, carrots, and asparagus. It is used to control annual grasses and certain broadleaf weeds which interfere with growth, development, yield and quality of agricultural and horticultural crops by competing on nutrients, water and light. Where weed infestation is particularly bad, yield loss can ren ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Trifluralin
Trifluralin is a common pre-emergent selective herbicide, a dinitroaniline. With about used in the United States in 2001, and in 2012, it is one of the most widely used herbicides. Trifluralin is also used in Australia, New Zealand, Brazil and previously in the EU. Introduced in 1964, Trifluralin was the first organofluorine compound used as an agrochemical. Trifluralin is generally applied to the soil to control annual grass and broadleaf weed species. It inhibits root development by interrupting mitosis and controls weeds as they germinate. Trifluralin moves very little inside the plant, remaining in the roots. Discovery Selective herbicides were unavailable in the 1950s to protect soybean and cotton ( 2,4-DNP could have been used but had to be exactingly applied lest it destroy the crops), so Lilly Research Laboratories screened ~2000 compounds from 1958 to 1980 blindly looking for a result. Trifluralin was initially thought a failure, yet the plots stayed free of w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nature Portfolio
Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine. Nature Research's flagship publication is ''Nature'', a weekly multidisciplinary journal first published in 1869. It also publishes the ''Nature-''titled research journals, ''Nature Reviews'' journals (since 2000), society-owned academic journals, and a range of open access journals, including ''Scientific Reports'' and ''Nature Communications''. Springer Nature also publishes ''Scientific American'' in 16 languages, a magazine intended for the general public. In 2013, prior to the merger with Springer and the creation of Springer Nature, Nature Publishing Group's owner, Holtzbrinck Publishing Group, bought a controlling stake in Frontiers. Before Springer Nature was formed in 2015, Nature Research (as the Nature Publ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Genetics Society
The Genetics Society is a British learned society. It was founded by William Bateson and Edith Rebecca Saunders in 1919 and celebrated its centenary year in 2019. It is therefore one of the oldest learned societies devoted to genetics. Its membership of over 2000 consists of most of the UK's active professional geneticists, including researchers, teachers and students. Industry and publishing are also represented in the membership. The Genetics Society is a registered charity that organises scientific meetings to promote current research in genetics and genomics, and publishes primary research in genetics in the journals Heredity and Genes and Development. It supports students to attend meetings, sponsors research through fieldwork grants and student bursaries, and promotes the public understanding of genetics. Presidents of The Genetics Society Society publications The society publishes the scientific journal, journal ''Heredity (journal), Heredity'' in association with Natu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Heredity (journal)
''Heredity'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. It covers heredity in a biological sense, i.e. genetics. The journal was founded by Ronald Fisher and C. D. Darlington in 1947 and is the official journal of The Genetics Society. From 1996 the publishing was taken over by Nature Portfolio. The editor-in-chief is Sara Goodacre. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 3.832, ranking it 61st out of 173 journals in the category "Ecology", 19th out of 51 journals in the category "Evolutionary Biology", and 79th out of 175 journals in the category "Genetics & Heredity". References External links * The Genetics Society* Genetics in the Unit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Arabidopsis Thaliana
''Arabidopsis thaliana'', the thale cress, mouse-ear cress or arabidopsis, is a small plant from the mustard family (Brassicaceae), native to Eurasia and Africa. Commonly found along the shoulders of roads and in disturbed land, it is generally considered a weed. A winter annual with a relatively short lifecycle, ''A. thaliana'' is a popular model organism in plant biology and genetics. For a complex multicellular eukaryote, ''A. thaliana'' has a relatively small genome of around 135 Base pair#Length measurements, megabase pairs. It was the first plant to have its genome sequenced, and is an important tool for understanding the molecular biology of many plant traits, including flower development and phototropism, light sensing. Description ''Arabidopsis thaliana'' is an annual plant, annual (rarely biennial plant, biennial) plant, usually growing to 20–25 cm tall. The leaf, leaves form a rosette at the base of the plant, with a few leaves also on the flowering Plant ste ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fitness Cost
Fitness (often denoted w or ω in population genetics models) is a quantitative representation of individual reproductive success. It is also equal to the average contribution to the gene pool of the next generation, made by the same individuals of the specified genotype or phenotype. Fitness can be defined either with respect to a genotype or to a phenotype in a given environment or time. The fitness of a genotype is manifested through its phenotype, which is also affected by the developmental environment. The fitness of a given phenotype can also be different in different selective environments. With asexual reproduction, it is sufficient to assign fitnesses to genotypes. With sexual reproduction, recombination scrambles alleles into different genotypes every generation; in this case, fitness values can be assigned to alleles by averaging over possible genetic backgrounds. Natural selection tends to make alleles with higher fitness more common over time, resulting in Darwinian e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |