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Chemosis
Chemosis is the swelling (or edema) of the conjunctiva. The term derives from the Greek words ''cheme'' and ''-osis'', ''cheme'' meaning cockleshell due to the swollen conjunctiva resembling it, and ''-osis'' meaning condition. The swelling is due to the oozing of exudate from abnormally permeable capillaries. In general, chemosis is a nonspecific sign of eye irritation. The outer surface covering appears to have fluid in it. The conjunctiva becomes swollen and gelatinous in appearance. Often, the eye area swells so much that the eyes become difficult or impossible to close fully. Sometimes, it may also appear as if the iris has moved slightly backwards from the white part of the eye due to the fluid filled in the conjunctiva all over the eyes except the iris. The iris is not covered by this fluid and so it appears to be moved slightly inwards. Causes It is usually caused by allergies or viral infections, often inciting excessive eye rubbing. Chemosis is also included in t ...
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Cavernous Sinus Thrombosis
Cavernous sinus thrombosis (CST) is the formation of a blood clot within the cavernous sinus, a cavity at the base of the brain which drains deoxygenated blood from the brain back to the heart. This is a rare disorder and can be of two types–septic cavernous thrombosis and aseptic cavernous thrombosis. The most common form is septic cavernous sinus thrombosis. The cause is usually from a spreading infection in the nose, sinuses, ears, or teeth. ''Staphylococcus aureus'' and ''Streptococcus'' are often the associated bacteria. Cavernous sinus thrombosis symptoms include: decrease or loss of vision, chemosis, exophthalmos (bulging eyes), headaches, and paralysis of the cranial nerves which course through the cavernous sinus. This infection is life-threatening and requires immediate treatment, which usually includes antibiotics and sometimes surgical drainage. Aseptic cavernous sinus thrombosis is usually associated with trauma, dehydration, anemia, and other disorders. Signs and ...
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Conjunctiva
In the anatomy of the eye, the conjunctiva (: conjunctivae) is a thin mucous membrane that lines the inside of the eyelids and covers the sclera (the white of the eye). It is composed of non-keratinized, stratified squamous epithelium with goblet cells, stratified columnar epithelium and stratified cuboidal epithelium (depending on the zone). The conjunctiva is highly Angiogenesis, vascularised, with many microvessels easily accessible for imaging studies. Structure The conjunctiva is typically divided into three parts: Blood supply Blood to the bulbar conjunctiva is primarily derived from the ophthalmic artery. The blood supply to the palpebral conjunctiva (the eyelid) is derived from the external carotid artery. However, the circulations of the bulbar conjunctiva and palpebral conjunctiva are linked, so both bulbar conjunctival and palpebral conjunctival vessels are supplied by both the ophthalmic artery and the external carotid artery, to varying extents. Nerve supply Se ...
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Phenacyl Chloride
Phenacyl chloride, also commonly known as chloroacetophenone, is a substituted acetophenone. It is a useful building block in organic chemistry. Apart from that, it has been historically used as a riot control agent, where it is designated CN. It should not be confused with cyanide, another agent used in chemical warfare, which has the chemical structure CN−. Chloroacetophenone is thermally stable, and is the only tear agent that is distillable at ambient conditions. Preparation Chloroacetophenone was first synthetized by Carl Graebe in 1871 by passing chlorine into boiling acetophenone. Phenacyl chloride is readily available and was first prepared by chlorination of acetophenone vapour. It may also be synthesized by the Friedel-Crafts acylation of benzene using chloroacetyl chloride, with an aluminium chloride catalyst: : Riot control agent It was investigated, but not used, during the First and Second World Wars (it was used as a "green agent" by the former Japanese mil ...
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Spitting Cobra
A "spitting" cobra is any of several species of cobra that can intentionally, defensively shoot their snake venom, venom directly from their fangs. This substance has two functions, with the first being as venom that can be absorbed via the victim’s eyes, mouth, or nose (or any mucous membrane or existing wound), and secondly as a toxungen, which can be sprayed on the target surface. Their ability to target and shoot venom is utilised in several different ways, self-defense being the most common instance. Studies have shown that the targets (at which the cobras shoot) are far from random; rather, spitting cobras consciously take aim, directing their spray to the eyes and face of an aggressor with 90% accuracy. In a remarkable case of convergent evolution, the individual cobra species evolved the ability to spit venom independently. Background Spitting cobras belong to the Elapidae, which comprises snakes including cobras, mambas, coral snakes, kraits, taipans, death adders ...
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Lid Lag
Lid lag is the static situation in which the upper eyelid An eyelid ( ) is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. "Palpebral ... is higher than normal with the globe in downgaze. It is most often a sign of thyroid eye disease, but may also occur with cicatricial changes to the eyelid or congenital ptosis. Lid lag differs from Von Graefe's sign in that the latter is a dynamic process. It can also be the manifestation of chemosis (swelling (or edema) of the conjunctiva). References Eye diseases {{Med-sign-stub ...
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Papilledema
Papilledema or papilloedema is optic disc swelling that is caused by increased intracranial pressure due to any cause. The swelling is usually bilateral and can occur over a period of hours to weeks. Unilateral presentation is extremely rare. In intracranial hypertension, the optic disc swelling most commonly occurs bilaterally. When papilledema is found on fundoscopy, further evaluation is warranted because vision loss can result if the underlying condition is not treated. Further evaluation with a CT scan or MRI of the brain and/or spine is usually done. Recent research has shown that point-of-care ultrasound can be used to measure optic nerve sheath diameter for detection of increased intracranial pressure and shows good diagnostic test accuracy compared to CT. Thus, if there is a question of papilledema on fundoscopic examination or if the optic disc cannot be adequately visualized, ultrasound can be used to rapidly assess for increased intracranial pressure and help direct f ...
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Eye Diseases
This is a partial list of human eye diseases and disorders. The World Health Organization (WHO) publishes a classification of known diseases and injuries, the International Statistical Classification of Diseases and Related Health Problems, or ICD-10. This list uses that classification. H00-H06 Disorders of eyelid, lacrimal system and orbit * (H02.1) Ectropion * (H02.2) Lagophthalmos * (H02.3) Blepharochalasis * (H02.4) Ptosis (eyelid), Ptosis * (H02.5) Stye, an acne type infection of the sebaceous glands on or near the eyelid. * (H02.6) Xanthelasma of eyelid * (H03.0*) Parasitic infestation of eyelid in diseases classified elsewhere ** Dermatitis of eyelid due to Demodex species ( B88.0+ ) ** Parasitic infestation of eyelid in: *** leishmaniasis ( B55.-+ ) *** loiasis ( B74.3+ ) *** onchocerciasis ( B73+ ) *** phthiriasis ( B85.3+ ) * (H03.1*) Involvement of eyelid in other infectious diseases classified elsewhere ** Involvement of eyelid in: *** herpesviral (herpes simplex) ...
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Dacryocystitis
Dacryocystitis is an infection of the lacrimal sac, secondary to obstruction of the nasolacrimal duct at the junction of the lacrimal sac. The term derives . It causes pain, redness, and swelling over the inner aspect of the lower eyelid and epiphora. When nasolacrimal duct obstruction is secondary to a congenital barrier it is referred to as dacryocystocele. It is most commonly caused by ''Staphylococcus aureus'' and ''Streptococcus pneumoniae''. The most common complication is corneal ulceration, frequently in association with ''S. pneumoniae''. The mainstays of treatment are oral antibiotics, warm compresses, and relief of nasolacrimal duct obstruction by dacryocystorhinostomy. Signs and symptoms *Pain, swelling, redness over the lacrimal sac at medial canthus *Tearing, crusting, fever *Digital pressure over the lacrimal sac may extrude pus through the punctum (also called ''roplas test'' positive) *In chronic cases, tearing may be the only symptom Pathophysiology A va ...
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Glaucoma
Glaucoma is a group of eye diseases that can lead to damage of the optic nerve. The optic nerve transmits visual information from the eye to the brain. Glaucoma may cause vision loss if left untreated. It has been called the "silent thief of sight" because the loss of vision usually occurs slowly over a long period of time. A major risk factor for glaucoma is increased pressure within the eye, known as Intraocular pressure, intraocular pressure (IOP). It is associated with old age, a family history of glaucoma, and certain medical conditions or the use of some medications. The word ''glaucoma'' comes from the Ancient Greek word (), meaning 'gleaming, blue-green, gray'. Of the different types of glaucoma, the most common are called open-angle glaucoma and closed-angle glaucoma. Inside the eye, a liquid called Aqueous humour, aqueous humor helps to maintain shape and provides nutrients. The aqueous humor normally drains through the trabecular meshwork. In open-angle glaucoma, ...
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Angioedema
Angioedema is an area of swelling (edema) of the lower layer of skin and tissue just under the skin or mucous membranes. The swelling may occur in the face, tongue, larynx, abdomen, or arms and legs. Often it is associated with hives, which are swelling within the upper skin. Onset is typically over minutes to hours. The underlying mechanism typically involves histamine or bradykinin. The version related to histamine is due to an allergic reaction to agents such as insect bites, foods, or medications. The version related to bradykinin may occur due to an inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme inhibitors, or a lymphoproliferative disorder. Treatment to protect the airway may include intubation or cricothyroidotomy. Histamine-related angioedema can be treated with antihistamines, corticosteroids, and epinephrine. In those with bradykinin-related disease a C1 esterase inhibitor, ecallantide, or icati ...
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Systemic Lupus Erythematosus
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus. The cause of SLE is not clear. It is thought to involve a combination of genetics and environmental factors. Among identical twins, if one is affected there is a 24% chance the other one will also develop the disease. Female sex hormones, sunlight, smoking, vitamin D deficiency, and certain infections are also believed to increa ...
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Trichinellosis
Trichinosis, also known as trichinellosis, is a parasitic disease caused by roundworms of the ''Trichinella'' genus. During the initial infection, invasion of the intestines can result in diarrhea, abdominal pain, and vomiting. Migration of larvae to muscle, which occurs about a week after being infected, can cause swelling of the face, inflammation of the whites of the eyes, fever, muscle pains, and a rash. Minor infection may be without symptoms. Complications may include inflammation of heart muscle, central nervous system involvement, and inflammation of the lungs. Trichinosis is mainly spread when undercooked meat containing ''Trichinella'' cysts is eaten. Wild meat is more likely to contain the parasite. In North America this is most often bear, but infection can also occur from pork, boar, and dog meat. Several species of ''Trichinella'' can cause disease, with ''T. spiralis'' being the most common. After the infected meat has been eaten, the larvae are released f ...
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