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Cerebellar Hypoplasia
Cerebellar hypoplasia is characterized by reduced cerebellar volume, even though cerebellar shape is (near) normal. It consists of a heterogeneous group of disorders of cerebellum, cerebellar maldevelopment presenting as early-onset Non-progressive congenital ataxia, non–progressive congenital ataxia, hypotonia and Developmental coordination disorder, motor learning disability. Various causes have been identified, including heredity, hereditary, metabolism, metabolic, toxin, toxic and virus, viral agents. It was first reported by French neurologist Octave Crouzon in 1929. In 1940, an unclaimed body came for dissection in London Hospital and was discovered to have no cerebellum. This unique case was appropriately named "human brain without a cerebellum" and was used every year in the Department of Anatomy at Cambridge University in a neuroscience course for medical students. Cerebellar hypoplasia can sometimes present alongside hypoplasia of the corpus callosum or pons. It can ...
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Cerebellar
The cerebellum (: cerebella or cerebellums; Latin for 'little brain') is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as it or even larger. In humans, the cerebellum plays an important role in motor control and cognitive functions such as attention and language as well as emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning in humans. Anatomically, the human cerebellum has the appearance of a separate structure attached to th ...
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Cerebellum
The cerebellum (: cerebella or cerebellums; Latin for 'little brain') is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as it or even larger. In humans, the cerebellum plays an important role in motor control and cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine motor skill, fine movement, sense of balance, equilibrium, list of human positions, posture, and motor learning in humans. ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to form images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, although ...
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Sagittal Plane
The sagittal plane (; also known as the longitudinal plane) is an anatomical plane that divides the body into right and left sections. It is perpendicular to the transverse and coronal planes. The plane may be in the center of the body and divide it into two equal parts ( mid-sagittal), or away from the midline and divide it into unequal parts (para-sagittal). The term ''sagittal'' was coined by Gerard of Cremona. Variations in terminology Examples of sagittal planes include: * The terms '' median plane'' or ''mid-sagittal plane'' are sometimes used to describe the sagittal plane running through the midline. This plane cuts the body into halves (assuming bilateral symmetry), passing through midline structures such as the navel and spine. It is one of the planes which, combined with the umbilical plane, defines the four quadrants of the human abdomen. * The term ''parasagittal'' is used to describe any plane parallel or adjacent to a given sagittal plane. Specific named pa ...
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Coronal Plane
The dorsal plane (also known as the coronal plane or frontal plane, especially in human anatomy) is an anatomical plane that divides the body into Anatomical terms of location#Dorsal and ventral, dorsal and ventral sections. It is perpendicular to the sagittal plane, sagittal and transverse plane, transverse planes. Human anatomy The coronal plane is an example of a Anatomical terms of location#General usage, longitudinal plane. For a human, the mid-coronal plane would transect a standing body into two halves (front and back, or anterior and posterior) in an imaginary line that cuts through both shoulders. The sternal plane (''planum sternale'') is a coronal plane which transects the front of the Human sternum, sternum. Etymology The term is derived from Latin ''corona'' ('garland, crown'), from Ancient Greek κορώνη (''korōnē'', 'garland, wreath'). The coronal plane is so called because it lies in the same direction as the coronal suture. Additional images File:Coronal ...
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Axial Plane
A transverse plane is a plane that is rotated 90° from two other planes. Anatomy The transverse plane is an anatomical plane that is perpendicular to the sagittal plane and the dorsal plane. It is also called the axial plane or horizontal plane, especially in human anatomy, but horizontal plane can be misleading with other animals. The plane splits the body into a cranial (head) side and caudal (tail) side, so in humans the plane will be horizontal (dividing the body into superior and inferior sections) but in quadrupeds it will be vertical. Human anatomy Clinically relevant anatomical planes * Transverse ''thoracic plane'' * '' Xiphosternal plane'' (or xiphosternal junction) * '' Transpyloric plane'' * '' Subcostal plane'' * '' Umbilical plane'' (or transumbilical plane) * '' Supracristal plane'' * '' Intertubercular plane'' (or transtubercular plane) * '' Interspinous plane'' Associated structures * The transverse ''thoracic plane'' ** Plane through T4 & T5 vertebral ...
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Ataxia
Ataxia (from Greek α- negative prefix+ -τάξις rder= "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum. These nervous system dysfunctions occur in several different patterns, with different results and different possible causes. Ataxia can be limited to one side of the body, which is referred to as hemiataxia. Friedreich's ataxia has gait abnormality as the most commonly presented symptom. Dystaxia is a mild degree of ataxia. Types Cerebellar The term cerebellar ataxia is used to indicate ataxia due to dysfunction of the cerebellum. The cerebellum is responsible for integrating a significant amount of neural information that is used to coordinate smoothly ongoing movements and to participate in motor planning. A ...
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Dandy–Walker Malformation
Dandy–Walker malformation (DWM), also known as Dandy–Walker syndrome (DWS), is a rare congenital brain malformation in which the part joining the two hemispheres of the cerebellum (the cerebellar vermis) does not fully form, and the fourth ventricle and space behind the cerebellum (the posterior fossa) are enlarged with cerebrospinal fluid. Most of those affected develop hydrocephalus within the first year of life, which can present as increasing head size, vomiting, excessive sleepiness, irritability, downward deviation of the eyes and seizures. Other, less common symptoms are generally associated with comorbid genetic conditions and can include congenital heart defects, eye abnormalities, intellectual disability, congenital tumours, other brain defects such as agenesis of the corpus callosum, skeletal abnormalities, an occipital encephalocele or underdeveloped genitalia or kidneys. It is sometimes discovered in adolescents or adults due to mental health problems. D ...
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Fourth Ventricle
The fourth ventricle is one of the four connected fluid-filled cavities within the human brain. These cavities, known collectively as the ventricular system, consist of the left and right lateral ventricles, the third ventricle, and the fourth ventricle. The fourth ventricle extends from the cerebral aqueduct (''aqueduct of Sylvius'') to the obex, and is filled with cerebrospinal fluid (CSF). The fourth ventricle has a characteristic diamond shape in cross-sections of the human brain. It is located within the pons or in the upper part of the medulla oblongata. CSF entering the fourth ventricle through the cerebral aqueduct can exit to the subarachnoid space of the spinal cord through two lateral apertures and a single, midline median aperture. Boundaries The fourth ventricle has a roof at its ''upper'' (posterior) surface and a floor at its ''lower'' (anterior) surface, and side walls formed by the cerebellar peduncles (nerve bundles joining the structure on the post ...
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Hydrocephalus
Hydrocephalus is a condition in which cerebrospinal fluid (CSF) builds up within the brain, which can cause pressure to increase in the skull. Symptoms may vary according to age. Headaches and double vision are common. Elderly adults with normal pressure hydrocephalus (NPH) may have poor balance, difficulty controlling urination, or mental impairment. In babies, there may be a rapid increase in head size. Other symptoms may include vomiting, sleepiness, seizures, and downward pointing of the eyes. Hydrocephalus can occur due to birth defects (primary) or can develop later in life (secondary). Hydrocephalus can be classified via mechanism into communicating, noncommunicating, ''ex vacuo'', and normal pressure hydrocephalus. Diagnosis is made by physical examination and medical imaging, such as a CT scan. Hydrocephalus is typically treated through surgery. One option is the placement of a shunt system. A procedure called an endoscopic third ventriculostomy has gained ...
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Pons
The pons (from Latin , "bridge") is part of the brainstem that in humans and other mammals, lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75). This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus. Structure The pons in humans measures about in length. It is the part of the brainstem situated between the midbrain and the medulla oblongata. The horizontal ''medullopontine sulcus'' demarcates the boundary between the pons and medulla oblongata on the ventral aspect of the brainstem, and the roots of cranial nerves VI/VII/VIII emerge from the brainstem along this groove. The junction of pons, medulla oblongata, and cerebellum forms the cerebellopontine ...
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