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Cat Coat Genetics
Cat coat genetics determine the coloration, pattern, length, and texture of feline fur. The variations among cat coats are physical properties and should not be confused with cat breeds. A cat may display the coat of a certain breed without actually being that breed. For example, a Neva Masquerade (Siberian cat, Siberian colorpoint) could wear point coloration, the stereotypical coat of a Siamese cat, Siamese. Solid colors Eumelanin and phaeomelanin Eumelanin The browning gene ''B/b/bl'' codes for TYRP1 (), an enzyme involved in the metabolic pathway for eumelanin pigment production. Its dominant form, ''B'', will produce black eumelanin. It has two recessive variants, ''b'' (chocolate) and ''bl'' (cinnamon), with ''bl'' being recessive to both ''B'' and ''b''. Chocolate is a rich dark brown color, and is referred to as chestnut in some breeds. Cinnamon is a light brown which may be a reddish color. Sex-linked red The sex-linked red ''"Orange"'' locus, ''O/o'', det ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanophilin
Melanophilin is a carrier protein which in humans is encoded by the ''MLPH'' gene. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Function This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. In melanocytic cells MLPH gene expression may be regulated by MITF. Clinical significance A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Mutations in melanophilin cause the "dilute" coat col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asparagine
Asparagine (symbol Asn or N) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a side chain carboxamide, classifying it as a polar (at physiological pH), aliphatic amino acid. It is non-essential in humans, meaning the body can synthesize it. It is encoded by the codons AAU and AAC. The one-letter symbol N for asparagine was assigned arbitrarily, with the proposed mnemonic asparagi''N''e; History Asparagine was first isolated in 1806 in a crystalline form by French chemists Louis Nicolas Vauquelin and Pierre Jean Robiquet (then a young assistant). It was isolated from asparagus juice, in which it is abundant, hence the chosen name. It was the first amino acid to be isolated. Three years later, in 1809, Pierre Jean Robiquet identified a substance from l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form when dissolved in water), a carboxyl group (which is in the deprotonated −COO− form when dissolved in water), and a side chain containing a hydroxyl group, making it a polar, uncharged amino acid. It is essential in humans, meaning the body cannot synthesize it: it must be obtained from the diet. Threonine is synthesized from aspartate in bacteria such as ''E. coli''. It is encoded by all the codons starting AC (ACU, ACC, ACA, and ACG). Threonine sidechains are often hydrogen bonded; the most common small motifs formed are based on interactions with serine: ST turns, ST motifs (often at the beginning of alpha helices) and ST staples (usually at the middle of alpha helices). Modifications The threonine residue is susceptible to numerous posttranslational modifications. The hydroxyl side-chain can und ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LVRN (gene)
Love Renaissance (LVRN) is an American record label and management company founded by Carlon Ramong, Justice Baiden, Junia Abaidoo, Sean Famoso McNichol and Tunde Balogun, and based in Atlanta, Georgia. The label is currently distributed through The Orchard, a unit of Sony Music Sony Music Entertainment (SME), commonly known as Sony Music, is an American multinational music company owned by Japanese conglomerate Sony Group Corporation. It is the recording division of Sony Music Group, with the other half being the .... The label currently houses artists 6lack, Summer Walker, BRS Kash, Alex Vaughn, Eli Derby, the South African duo TxC and North Ave Jax. LVRN manages artists Shelley FKA DRAM, Westside Boogie, Dvsn, Davido, and Spinall. History Love Renaissance (LVRN) was founded in 2012 by rival party promoters Carlon Ramong, Justice Baiden, Junia Abaidoo, Sean Famoso McNichol, and Tunde Balogun while students at Georgia State University. The agency specializ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bengal - 18
Bengal ( ) is a historical geographical, ethnolinguistic and cultural term referring to a region in the eastern part of the Indian subcontinent at the apex of the Bay of Bengal. The region of Bengal proper is divided between the modern-day sovereign nation of Bangladesh and the Indian states of West Bengal, and Karimganj district of Assam. The ancient Vanga Kingdom is widely regarded as the namesake of the Bengal region. The Bengali calendar dates back to the reign of Shashanka in the 7th century CE. The Pala Empire was founded in Bengal during the 8th century. The Sena dynasty and Deva dynasty ruled between the 11th and 13th centuries. By the 14th century, Bengal was absorbed by Muslim conquests in the Indian subcontinent. An independent Bengal Sultanate was formed and became the eastern frontier of the Islamic world. During this period, Bengal's rule and influence spread to Assam, Arakan, Tripura, Bihar, and Odisha (formerly- Orissa).David Lewis (31 October 2011). Bangl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epistatic
Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears. Epistatic mutations therefore have different effects on their own than when they occur together. Originally, the term ''epistasis'' specifically meant that the effect of a gene variant is masked by that of different gene. The concept of ''epistasis'' originated in genetics in 1907 but is now used in biochemistry, computational biology and evolutionary biology. The phenomenon arises due to interactions, either between genes (such as mutations also being needed in regulators of gene expression) or within them (multiple mutations being needed before the gene loses function), leading to non-linear effects. Epistasis has a great influence on the shape of evolutionary landscapes, which leads ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agouti Signaling Protein
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. It is responsible for the distribution of melanin pigment in mammals. Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). This interaction is responsible for making distinct light and dark bands in the hairs of animals such as the agouti, which the gene is named after. In other species such as horses, agouti signalling is responsible for determining which parts of the body will be red or black. Mice with wildtype agouti will be grey-brown, with each hair being partly yellow and partly black. Loss of function mutations in mice and other species cause black fur coloration, while mutations causing expression throughout the whole body in mice cause yellow fur and obesity. The agouti-signaling protein (ASIP) is a competitive antagonist with alpha-Melanocyte-stimulati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agouti (coloration)
Agouti is a type of fur coloration in which each hair displays two or more bands of pigmentation. The overall appearance of agouti fur is usually gray or dull brown, although dull yellow is also possible. Agouti fur is characterized by an appearance of being composed of hairs of different colors, separate from definite markings (although agouti can appear in combination with other markings, such as spots, stripes or patches). This effect is caused by different ''portions'' of each hair being visible, such that different colors of the hair's banding are seen, despite hairs actually having similar coloration. This effect produces a very distinctive, finely "speckled" appearance similar to "salt and pepper" hair, as well as an iridescent effect very similar to shot silk which causes the overall color to appear to shift subtly depending on the angle of the light or when the animal moves. Agouti fur is the wild type pigmentation for many domesticated mammals. It is a highly re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poil Agouti
Poil () is a commune in the Nièvre department in central France. History The name of the locality was first recorded as ''Picti'' in the 10th century, then ''Poiz'' in 1281, ''Poys'' in the 14th century, ''Poy'' in 1414, and finally ''Poil'' in 1592. This development reflects a regular change from the root ''Picti-'' to ''Poi(z)-,'' similar to other Celtic place names. The root "Pict-" probably relates to the Picts, a people from Scotland, possibly in theme with foreign Roman legions stationed there (compare e.g. Mortagne and Sermaise, from Mauretania and Sarmatia respectively). The final "-l" was added later, influenced by the common noun "poil", a homophone (common in French) with ''Pois''. Geography The commune is part of the ''parc naturel régional du Morvan''. The river Alène has its source in the south-western part of the commune. Demographics On 1 January 2019, the estimated population was 147. See also *Communes of the Nièvre department A commune is an alterna ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CAT2007 05 16
The cat (''Felis catus''), also referred to as the domestic cat or house cat, is a small domesticated carnivorous mammal. It is the only domesticated species of the family Felidae. Advances in archaeology and genetics have shown that the domestication of the cat occurred in the Near East around 7500 BC. It is commonly kept as a pet and working cat, but also ranges freely as a feral cat avoiding human contact. It is valued by humans for companionship and its ability to kill vermin. Its retractable claws are adapted to killing small prey species such as mice and rats. It has a strong, flexible body, quick reflexes, and sharp teeth, and its night vision and sense of smell are well developed. It is a social species, but a solitary hunter and a crepuscular predator. Cat intelligence is evident in their ability to adapt, learn through observation, and solve problems. Research has shown they possess strong memories, exhibit neuroplasticity, and display cognitive skills comparable t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Persian Cat
The Persian cat, also known as the Persian Longhair, is a long-haired breed of cat characterised by a round face and short muzzle. The first documented ancestors of Persian cats might have been imported into Italy from Greater Khorasan, Khorasan as early as around 1620, but this has not been proven. Instead, there is stronger evidence for a longhaired cat breed being exported from Afghanistan and Iran, Iran/Persia from the 19th century onwards. Persian cats have been widely recognised by the North-West European Cat culture, cat fancy since the 19th century, and after World War II by breeders from North America, Australia and New Zealand. Some cat fancier organisations' breed standards subsume the Himalayan cat, Himalayan and Exotic Shorthair as variants of this breed, while others generally treat them as separate breeds. The selective breeding carried out by breeders has allowed the development of a wide variety of coat colours, but has also led to the creation of increasingly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
