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California Sea Hare
The California sea hare (''Aplysia californica'') is a species of sea slug in the sea hare family, Aplysiidae.Rosenberg, G.; Bouchet, P. (2011). Aplysia californica J. G. Cooper, 1863. Accessed through: World Register of Marine Species at http://www.marinespecies.org/aphia.php?p=taxdetails&id=240765 on 2012-03-31 It is found in the Pacific Ocean, off the coast of California in the United States and northwestern Mexico. Distribution ''A. californica'' is found along the coast of California, United States, and northwestern Mexico (including the Gulf of California). ''Aplysia'' species inhabit the photic zone to graze on algae, mainly the intertidal, usually not deeper than . Description The maximum length recorded for the California sea hare is when crawling, thus fully extended, although most adult specimens are half this size or smaller. Adult animals can weigh up to . A closely related species, ''Aplysia vaccaria'', the black sea hare, can grow larger still. A California sea h ...
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James Graham Cooper
James Graham Cooper (June 19, 1830 – July 19, 1902) was an American surgeon and naturalist. Cooper was born in New York. He worked for the California Geological Survey (1860–1874) with Josiah Dwight Whitney, William Henry Brewer and Henry Nicholas Bolander. He was primarily a zoologist, but he also made significant Botany, botanical collections from San Diego to Fort Mohave, Arizona in 1861. Cooper was active in the California Academy of Sciences, eventually becoming Director of the Museum. He obtained his medical degree in 1851 and practiced in New York City until 1853. Spencer F. Baird, the Assistant Secretary of the Smithsonian Institution at that time, helped Cooper work with the Pacific railroad survey parties working in the Washington Territory. He joined this survey under Captain George McClellan as a surgeon until 1854. In 1855 he visited San Francisco and the Panama Isthmus. He collected many birds during this expedition. In 1860, he returned west and joined the Bla ...
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Navanax Inermis
''Navanax inermis'', common name the California aglaja, is a large species of predatory sea slug, a marine opisthobranch gastropod mollusk in the family Aglajidae. ''Navanax'' is not a nudibranch, even though it somewhat resembles one; it belongs to a more ancient lineage of opisthobranchs called the cephalaspideans or head shield slugs and snails. Description The body of ''N. inermis'' can be tan, black, or purple, with yellowish streaks. Yellow or orange streaks and blue dots are visible on the margins. It has two large parapodial folds that run the length of either side of the body, and almost touch at the midsection. This species possesses a small internal shell. Individuals are typically between 2.5 and 10 inches in length. ''Navanax inermis'' does not possess a radula or organs associated with vision. Distribution and habitat This species occurs in the eastern Pacific Ocean and Gulf of California. Its range is from Monterey, California to Baja California Baja Calif ...
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Sensitization
Sensitization is a non-associative learning process in which repeated administration of a stimulation, stimulus results in the progressive amplification of a response. Sensitization often is characterized by an enhancement of response to a whole class of stimuli in addition to the one that is repeated. For example, repetition of a painful stimulus may make one more responsive to a loud noise. History Eric Kandel was one of the first to study the neural basis of sensitization, conducting experiments in the 1960s and 1970s on the gill withdrawal reflex of the seaslug ''Aplysia''. Kandel and his colleagues first habituated the reflex, weakening the response by repeatedly touching the animal's siphon. They then paired noxious electrical stimulus to the tail with a touch to the siphon, causing the gill withdrawal response to reappear. After this sensitization, a light touch to the siphon alone produced a strong gill withdrawal response, and this sensitization effect lasted for several ...
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Neuron
A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural network in the nervous system. They are located in the nervous system and help to receive and conduct impulses. Neurons communicate with other cells via synapses, which are specialized connections that commonly use minute amounts of chemical neurotransmitters to pass the electric signal from the presynaptic neuron to the target cell through the synaptic gap. Neurons are the main components of nervous tissue in all Animalia, animals except sponges and placozoans. Plants and fungi do not have nerve cells. Molecular evidence suggests that the ability to generate electric signals first appeared in evolution some 700 to 800 million years ago, during the Tonian period. Predecessors of neurons were the peptidergic secretory cells. They eventually ga ...
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Nervous System
In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in Ediacara biota, wormlike organisms about 550 to 600 million years ago. In Vertebrate, vertebrates, it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers, or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves (efferent), while those nerves that transmit information from the body to the CNS are called sensory nerves (aff ...
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Synaptic Plasticity
In neuroscience, synaptic plasticity is the ability of synapses to Chemical synapse#Synaptic strength, strengthen or weaken over time, in response to increases or decreases in their activity. Since memory, memories are postulated to be represented by vastly interconnected neural circuits in the brain, synaptic plasticity is one of the important neurochemical foundations of learning and memory (''see Hebbian theory''). Plastic change often results from the alteration of the number of neurotransmitter receptors located on a synapse. There are several underlying mechanisms that cooperate to achieve synaptic plasticity, including changes in the quantity of neurotransmitters released into a synapse and changes in how effectively cells respond to those neurotransmitters. Synaptic plasticity in both Excitatory synapse, excitatory and Inhibitory synapse, inhibitory synapses has been found to be dependent upon postsynaptic calcium release. Historical discoveries In 1973, Terje Lømo and ...
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Eric Kandel
Eric Richard Kandel (; born Erich Richard Kandel, November 7, 1929) is an Austrian-born American medical doctor who specialized in psychiatry, a neuroscientist and a professor of biochemistry and biophysics at the College of Physicians and Surgeons at Columbia University. He was a recipient of the 2000 Nobel Prize in Physiology or Medicine for his research on the physiological basis of memory storage in neurons. He shared the prize with Arvid Carlsson and Paul Greengard. Kandel was from 1984 to 2022 a Senior Investigator in the Howard Hughes Medical Institute. He was in 1975 the founding director of the Center for Neurobiology and Behavior, which is now the Department of Neuroscience at Columbia University. He currently serves on the Scientific Council of the Brain & Behavior Research Foundation. Kandel's popularized account chronicling his life and research, ''In Search of Memory: The Emergence of a New Science of Mind'', was awarded the 2006 ''Los Angeles Times'' Book Prize ...
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Nobel Laureate
The Nobel Prizes (, ) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in the fields of chemistry, physics, literature, peace, and physiology or medicine. They were established by the 1895 will of Alfred Nobel, which dictates that the awards should be administered by the Nobel Foundation. An additional prize in memory of Alfred Nobel was established in 1968 by Sveriges Riksbank (Sweden's central bank) for outstanding contributions to the field of economics. Each recipient, a Nobelist or '' laureate'', receives a gold medal, a diploma, and a sum of money which is decided annually by the Nobel Foundation. Prize Different organisations are responsible for awarding the individual prizes; the Royal Swedish Academy of Sciences awards the Prizes in Physics, Chemistry, and Economics; the Swedish Academy awards the ...
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Memory
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered, it would be impossible for language, relationships, or personal identity to develop. Memory loss is usually described as forgetfulness or amnesia. Memory is often understood as an informational processing system with explicit and implicit functioning that is made up of a sensory processor, short-term (or working) memory, and long-term memory. This can be related to the neuron. The sensory processor allows information from the outside world to be sensed in the form of chemical and physical stimuli and attended to various levels of focus and intent. Working memory serves as an encoding and retrieval processor. Information in the form of stimuli is encoded in accordance with explicit or implicit functions by the working memory p ...
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Learning
Learning is the process of acquiring new understanding, knowledge, behaviors, skills, value (personal and cultural), values, Attitude (psychology), attitudes, and preferences. The ability to learn is possessed by humans, non-human animals, and some machine learning, machines; there is also evidence for some kind of learning in certain plants. Some learning is immediate, induced by a single event (e.g. being burned by a Heat, hot stove), but much skill and knowledge accumulate from repeated experiences. The changes induced by learning often last a lifetime, and it is hard to distinguish learned material that seems to be "lost" from that which cannot be retrieved. Human learning starts at birth (it might even start before) and continues until death as a consequence of ongoing interactions between people and their environment. The nature and processes involved in learning are studied in many established fields (including educational psychology, neuropsychology, experimental psycho ...
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Neurobiology
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging of Sen ...
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Model Organism
A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. Research using animal models has been central to most of the achievements of modern medicine. It has contributed most of the basic knowledge in fields such as human physiology and biochemistry, and has played significant roles in fields such as neuroscience and infectious disease. The results have included the near- eradication of polio and the development of organ transplantation, and have benefited both humans and animals. From 19 ...
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