Caffeoylquinic Acids
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Caffeoylquinic Acids
Caffeoylquinic acids (CQA) are compounds composed of a quinic acid core, acylated with one or more caffeoyl groups. There is a positive correlation between the number of caffeoyl groups bound to quinic acid and the rate of ATP production. Compounds of this class include: * Chlorogenic acid Chlorogenic acid (CGA) is the ester of caffeic acid and quinic acid, functioning as an intermediate in lignin biosynthesis. The term chlorogenic acids refers to a related polyphenol family of esters, including hydroxycinnamic acids ( caffeic a ... (3-''O''-caffeoylquinic acid or 3-CQA) * 4-''O''-caffeoylquinic acid (crypto-chlorogenic acid or 4-CQA) * 5-O-caffeoylquinic acid, 5-''O''-caffeoylquinic acid (neo-chlorogenic acid or 5-CQA) * 1,5-diCQA * 3,4-diCQA * 3,5-diCQA * 4,5-diCQA References

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Quinic Acid
Quinic acid is an organic compound with the formula . The compound is classified as a cyclitol, a cyclic polyol, and a cyclohexanecarboxylic acid. It is a colorless solid that can be extracted from plant sources. Quinic acid is implicated in the perceived acidity of coffee, where it occurs around 13% by weight. Occurrence and preparation The compound is obtained from cinchona bark, coffee beans, and the bark of ''Eucalyptus globulus''. It is a constituent of the tara tannins. ''Urtica dioica'', the European stinging nettle, is another common source. It is made synthetically by hydrolysis of chlorogenic acid. Quinic acid is also implicated in the perceived acidity of coffee. History and biosynthesis This substance was isolated for the first time in 1790 by German pharmacist Friedrich Christian Hofmann in Leer from Cinchona. Its transformation into hippuric acid by animal metabolism was studied by German chemist Eduard Lautemann in 1863.Lautemann, E. (1863"Ueber die Reduc ...
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