|
Bombykol
Bombykol is a pheromone released by the female silkworm moth to attract mates. It is also the sex pheromone in the wild silk moth ('' Bombyx mandarina''). Discovered by Adolf Butenandt in 1959, it was the first pheromone to be characterized chemically. Minute quantities of this pheromone can be used per acre of land to confuse male insects about the location of their female partners. It can thus serve as a lure in traps to remove insects effectively without spraying crops with large amounts of pesticides. Butenandt named the substance after the moth's Latin name ''Bombyx mori.'' ''In vivo'' it appears that bombykol is the natural ligand for a pheromone binding protein, BmorPBP, which escorts the pheromone to the pheromone receptor. Biosynthesis Bombykol is known to be derived from acetyl-CoA Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function is to deliver the acetyl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bombykol Biosynthesis Pathway
Bombykol is a pheromone released by the female silkworm moth to attract mates. It is also the sex pheromone in the wild silk moth (''Bombyx mandarina''). Discovered by Adolf Butenandt in 1959, it was the first pheromone to be characterized chemically. Minute quantities of this pheromone can be used per acre of land to confuse male insects about the location of their female partners. It can thus serve as a lure in traps to remove insects effectively without spraying crops with large amounts of pesticides. Butenandt named the substance after the moth's Latin name ''Bombyx mori.'' ''In vivo'' it appears that bombykol is the natural ligand for a pheromone binding protein, BmorPBP, which escorts the pheromone to the pheromone receptor. Biosynthesis Bombykol is known to be derived from acetyl-CoA via the C-16 fatty acyl palmitoyl-CoA Palmitoyl-CoA is an acyl-CoA thioester. It is an "activated" form of palmitic acid and can be transported into the mitochondrial matrix by the car ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pheromone
A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavior of the receiving individuals. There are ''alarm signal, alarm pheromones'', ''food trail pheromones'', ''sex pheromones'', and many others that affect behavior or physiology. Pheromones are used by many organisms, from basic unicellular prokaryotes to complex multicellular eukaryotes. Their use among insects has been particularly well documented. In addition, some vertebrates, plants and ciliates communicate by using pheromones. The ecological functions and evolution of pheromones are a major topic of research in the field of chemical ecology. Background The portmanteau word "pheromone" was coined by Peter Karlson and Martin Lüscher in 1959, based on the Greek language, Greek () and (). Pheromones are also sometimes classified as ec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silkworm
''Bombyx mori'', commonly known as the domestic silk moth, is a moth species belonging to the family Bombycidae. It is the closest relative of '' Bombyx mandarina'', the wild silk moth. Silkworms are the larvae of silk moths. The silkworm is of particular economic value, being a primary producer of silk. The silkworm's preferred food are the leaves of white mulberry, though they may eat other species of mulberry, and even leaves of other plants like the Osage orange. Domestic silk moths are entirely dependent on humans for reproduction, as a result of millennia of selective breeding. Wild silk moths, which are other species of ''Bombyx'', are not as commercially viable in the production of silk. Sericulture, the practice of breeding silkworms for the production of raw silk, has existed for at least 5,000 years in China, whence it spread to India, Korea, Nepal, Japan, and then the West. The conventional process of sericulture kills the silkworm in the pupal stage. The domestic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adolf Butenandt
Adolf Friedrich Johann Butenandt (; 24 March 1903 – 18 January 1995) was a German biochemist. He was awarded the Nobel Prize in Chemistry in 1939 for his "work on sex hormones." He initially rejected the award in accordance with government policy, but accepted it in 1949 after World War II. He was President of the Max Planck Society from 1960 to 1972. He was also the first, in 1959, to discover the structure of the sex pheromone of silkworms, which he named bombykol. Education and early life Born in Lehe, near Bremerhaven, he started his studies at the University of Marburg. For his PhD he joined the working group of the Nobel laureate Adolf Windaus at the University of Göttingen and he finished his studies with a PhD in chemistry in 1927. His doctoral research was on the chemistry of the insecticidal toxin found in the roots of ''Derris elliptica'' which he isolated and characterized. After his Habilitation he became lecturer in Göttingen 1931. Professional career He beca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bombyx Mandarina
''Bombyx mandarina'', the wild silk moth, is a species of moth in the family Bombycidae. It is the closest relative of ''Bombyx mori'', the domesticated silk moth. The silkworm is the larva or caterpillar of a silk moth. Unlike the domesticated relative which is unable to fly or indeed persist outside human care, the wild silk moth is a fairly ordinary lepidopteran. Its main difference from the domesticated taxon is the more slender body with well-developed wings in males, and the dull greyish-brown colour. Phylogeny and systematics ''Bombyx mandarina'' and the domesticated ''Bombyx mori'' constitute two of the currently identified eight species of the genus ''Bombyx'', the true or mulberry silk moths. The origin of the domestic silk moth is enigmatic. It has been suggested that it is the survivor of an extinct species that diverged from the ancestors of ''Bombyx mandarina'' millions of years ago. However, this is based on an untenable molecular clock hypothesis that assumes tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoppe-Seyler's Zeitschrift Für Physiologische Chemie
''Biological Chemistry'' is a peer-reviewed scientific journal focusing on biological chemistry. The journal is published by Walter de Gruyter and the current editor-in-chief is Bernhard Brüne. History The journal was established by Felix Hoppe-Seyler in 1877, under the name ''Zeitschrift für Physiologische Chemie'' (English: ''Journal of Physiological Chemistry''), and was edited by him until his death in 1895. The journal was subsequently renamed '' Hoppe-Seyler's Zeitschrift für Physiologische Chemie'' in 1896. Following Hoppe-Seyler, the journal was edited by his student and collaborator, the German biochemist and Nobel laureate Albrecht Kossel, until his death in 1927. In 1985 the journal was renamed as ''Biological Chemistry Hoppe-Seyler'', before obtaining its current title in 1996. Abstracting and indexing ''Biological Chemistry'' is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2014 impact factor The impact facto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 80 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ''ligare'', which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix. The relationship between ligand and binding partner is a function of charge, hydrophobicity, and molecular structure. Binding occurs by intermolecular forces, such as ionic bonds, hydrogen bonds and Van der Waals forces. The association or docking is actually reversible through dissociation. Measurably irreversible covalent bonding between a ligand and target molecule is atypical in biological systems. In contrast to the definition o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetyl-CoA
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function is to deliver the acetyl group to the citric acid cycle (Krebs cycle) to be oxidation, oxidized for energy production. Coenzyme A (CoASH or CoA) consists of a cysteamine, β-mercaptoethylamine group linked to pantothenic acid (vitamin B5) through an amide linkage and 3'-phosphorylated ADP. The acetyl group (indicated in blue in the structural diagram on the right) of acetyl-CoA is linked to the sulfhydryl substituent of the β-mercaptoethylamine group. This thioester linkage is a "high energy" bond, which is particularly reactive. Hydrolysis of the thioester bond is exergonic (−31.5 kJ/mol). CoA is acetylated to acetyl-CoA by the breakdown of carbohydrates through glycolysis and by the breakdown of fatty acids through Beta oxidation, β-oxidation. Acetyl-CoA then enters the citric acid cycle, where the acetyl group is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Palmitoyl-CoA
Palmitoyl-CoA is an acyl-CoA thioester. It is an "activated" form of palmitic acid and can be transported into the mitochondrial matrix by the carnitine shuttle system (which transports fatty acyl-CoA molecules into the mitochondria), and once inside can participate in beta-oxidation. Alternatively, palmitoyl-CoA is used as a substrate in the biosynthesis of sphingosine (this biosynthetic pathway does not require transfer into the mitochondria). Biosynthesis Palmitoyl CoA formed from palmitic acid, in the reaction below. : This reaction is often referred to as the "activation" of a fatty acid. The activation is catalyzed by palmitoyl-coenzyme A synthetase and the reaction proceeds through a two step mechanism, in which palmitoyl-AMP is an intermediate. The reaction is driven to completion by the exergonic hydrolysis of pyrophosphate. The activation of fatty acids occurs in the cytosol and beta-oxidation occurs in the mitochondria. However, long chain fatty acyl-CoA cannot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insect Pheromones
Insect pheromones are neurotransmitters that serve the chemical communication between individuals of an insect species. They thus differ from kairomones, in other words, neurotransmitters that transmit information to non-species organisms. Insects produce pheromones in special glands and release them into the environment. In the pheromone receptors of the sensory cells of the recipient, they produce a nerve Stimulus (physiology), stimulus even in very low concentrations, which ultimately leads to a behavioral response. Biological specificity, Intraspecific communication of insects via these substances takes place in a variety of ways and serves, among other things, to find sexual partner, to maintain harmony in a Colony (biology), colony of Eusociality, socially living insects, to mark territories or to find nest sites and food sources. In 1959, the German biochemist and Nobel Prize winner Adolf Butenandt identified and synthesized the Saturated and unsaturated compounds, unsatura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
