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Bisalbuminemia
Bisalbuminemia is the, sometimes inherited, condition of having two types of serum albumin that differ in mobility during electrophoresis. It can be seen in densitometry Densitometry is the quantitative measurement of optical density in light-sensitive materials, such as photographic paper or photographic film, due to exposure to light. Overview Optical density is a result of the darkness of a developed pictu ... as a bifid mountain where albumin has 2 heads. Inherited bisalbuminemia has no pathologic effects, but is of interest to researchers who study the evolution and functional changes in the protein. References {{Reflist Albumin disorders ...
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Serum Albumin
Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood. Human serum albumin is encoded by the ''ALB'' gene. Other mammalian forms, such as bovine serum albumin, are chemically similar. Serum albumin is produced by the liver, occurs dissolved in blood plasma and is the most abundant blood protein in mammals. Albumin is essential for maintaining the oncotic pressure needed for proper distribution of body fluids between blood vessels and body tissues; without albumin, the high pressure in the blood vessels would force more fluids out into the tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids. Too much or too little circulating serum albumin may be harmful. Albumin in the urine usually denotes the presence of kidney disease. Occasionally albumin appears in the urine of normal persons following long peri ...
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Electrophoresis
Electrophoresis, from Ancient Greek ἤλεκτρον (ḗlektron, "amber") and φόρησις (phórēsis, "the act of bearing"), is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field. Electrophoresis of positively charged particles ( cations) is sometimes called cataphoresis, while electrophoresis of negatively charged particles (anions) is sometimes called anaphoresis. The electrokinetic phenomenon of electrophoresis was observed for the first time in 1807 by Russian professors Peter Ivanovich Strakhov and Ferdinand Frederic Reuss at Moscow University, who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid. It is the basis for analytical techniques used in chemistry for separating molecules by size, charge, or binding affinity. Electr ...
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Densitometry
Densitometry is the quantitative measurement of optical density in light-sensitive materials, such as photographic paper or photographic film, due to exposure to light. Overview Optical density is a result of the darkness of a developed picture and can be expressed absolutely as the number of dark spots (i.e., silver grains in developed films) in a given area, but usually it is a relative value, expressed in a scale. Since density is usually measured by the decrease in the amount of light which shines through a transparent film, it is also called ''absorptiometry'', the measure of light absorption through the medium. The corresponding measuring device is called a densitometer (''absorptiometer''). The decadic (base-10) logarithm of the reciprocal of the transmittance is called the absorbance or ''density''. ''DMax'' and ''DMin'' refer to the maximum and minimum density that can be produced by the material. The difference between the two is the ''density range''. The densit ...
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