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Biological Pathway
In cell biology, a biological pathway is a series of interactions among molecules in a cell that leads to a certain product or a change in the cell. Such a pathway can trigger the assembly of new molecules, such as a fat or protein. Pathways can also turn genes on and off, or spur a cell to move. Some of the most common biological pathways are involved in metabolism, the regulation of gene expression and the transmission of signals. Pathways play a key role in advanced studies of genomics. Types of biological pathways Most common types of biological pathways: *Metabolic pathway * Genetic pathway *Signal transduction pathway Neuroanatomy In neuroanatomy, a neural pathway is the connection formed by axons that project from neurons to make synapses onto neurons in another location, to enable neurotransmission (the sending of a signal from one region of the nervous system to another).{{Cite book, title = Clinically Oriented Anatomy, last1 = Moore, first1 = Keith, last2 = Dalley, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of the structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fiel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WikiPathways
WikiPathways is a community resource for contributing and maintaining content dedicated to biological pathways. Any registered WikiPathways user can contribute, and anybody can become a registered user. Contributions are monitored by a group of admins, but the bulk of peer review, editorial curation, and maintenance is the responsibility of the user community. WikiPathways is originally built using MediaWiki software, a custom graphical pathway editing tool ( PathVisio) and integrated BridgeDb databases covering major gene, protein, and metabolite systems. WikiPathways was founded in 2008 by Thomas Kelder, Alex Pico, Martijn Van Iersel, Kristina Hanspers, Bruce Conklin and Chris Evelo. Current architects are Alex Pico and Martina Summer-Kutmon. Pathway content Each article at WikiPathways is dedicated to a particular pathway. Many types of molecular pathways are covered, including metabolic, signaling, regulatory, etc. and the supported species include human, mouse, zebrafish, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathway Commons
Pathway Commons is a database of biological pathways and interactions. See also * Biological pathway * Reactome References External links pathwaycommons Biological databases Metabolism Systems biology {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Comparative Toxicogenomics Database
The Comparative Toxicogenomics Database (CTD) is a public website and research tool launched in November 2004 that curates scientific data describing relationships between chemicals/drugs, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules. The database is maintained by the Department of Biological Sciences at North Carolina State University. Background The Comparative Toxicogenomics Database (CTD) is a public website and research tool that curates scientific data describing relationships between chemicals, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules, launched on November 12, 2004. The database is maintained by the Department of Biological Sciences at North Carolina State University. Goals and objectives One of the primary goals of CTD is to advance the understanding of the effects of environmental chemicals on human health on the genetic level, a field called toxicogenomics. The etiolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EsyN
esyN (Easy Networks) is a bioinformatics web-tool for visualizing, building and analysing molecular interaction networks. esyN is based on cytoscape.js and its aim is to make it easy for everybody to perform network analysis. esyN is connected with a number of databases - specifically: pombase, flybase, and most InterMine data warehouses, DrugBank, and BioGRID from which its possible to download the protein protein or genetic interactions for any protein or gene in a number of different organisms. Networks published in esyN can be easily published in other websites using the methodology. Usage As of January 2016 esyN is being viewed by 1500 unique users a day (about 16000 a month) according to Google Analytics. The embedding capabilities of esyN are used by a number of databases to display their interaction data: * FlyBase * FlyMine * HumanMine * PomBase See also * Computational genomics * Metabolic network modelling * Protein–protein interaction prediction Protein– ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DrugBank
The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets created and maintained by the University of Alberta and The Metabolomics Innovation Centre located in Alberta, Canada. As both a bioinformatics and a cheminformatics resource, DrugBank combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. DrugBank has used content from Wikipedia; Wikipedia also often links to Drugbank, posing potential circular reporting issues. The DrugBank Online website is available to the public as a free-to-access resource. However, use and re-distribution of content from DrugBank Online or the underlying DrugBank Data, in whole or part, and for any purpose requires a license. Academic users can apply for a free license for certain use cases while all other users require a paid license. The latest release of the database (vers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MiRTarBase
miRTarBase is a curated database of MicroRNA-Target Interactions. As a database, miRTarBase has accumulated more than fifty thousand miRNA-target interactions (MTIs), which are collected by manually surveying pertinent literature after data mining of the text systematically to filter research articles related to functional studies of miRNAs. Generally, the collected MTIs are validated experimentally by reporter assay, western blot, microarray and next-generation sequencing experiments. While containing the largest amount of validated MTIs, the miRTarBase provides the most updated collection by comparing with other similar, previously developed databases. See also * MicroRNAs References External links Biological databases RNA MicroRNA {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TRANSFAC
TRANSFAC (TRANScription FACtor database) is a manually curated database of eukaryotic transcription factors, their genomic binding sites and DNA binding profiles. The contents of the database can be used to predict potential transcription factor binding sites. Introduction The origin of the database was an early data collection published 1988. The first version that was released under the name TRANSFAC was developed at the former German National Research Centre for Biotechnology and designed for local installation (now: Helmholtz Centre for Infection Research). In one of the first publicly funded bioinformatics projects, launched in 1993, TRANSFAC developed into a resource that became available on the Internet. In 1997, TRANSFAC was transferred to a newly established company, BIOBASE, in order to secure long-term financing of the database. Since then, the most up-to-date version has to be licensed, whereas older versions are free for non-commercial users. Since July 2016, TRAN ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PANTHER
Panther may refer to: Large cats *Pantherinae, the cat subfamily that contains the genera ''Panthera'' and ''Neofelis'' **''Panthera'', the cat genus that contains tigers, lions, jaguars and leopards ***Jaguar (''Panthera onca''), found in South and Central America ***Leopard (''Panthera pardus''), found in Africa and Asia ***Black panther, a name for the phenotypic genetic variant that forms the black leopard or jaguar *Cougar, a big cat that is not in the subfamily Pantherinae, but is commonly referred to as a panther **Florida panther, a population of cougar Art, media, and entertainment Video games * ''Panther'' (1975 video game), a battle tank-driving game developed for the PLATO system * ''Panther'' (1986 video game), a flight game developed for the Commodore 64 and Atari 800XL/130XE * Atari Panther, a cancelled video game console, expected to be released in the early 1990s * Panther, the codename for Ann Takamaki, a character from ''Persona 5'' Other media * ''Panth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Protein Reference Database
The Human Protein Reference Database (HPRD) is a protein database accessible through the Internet. It is closely associated with the premier Indian Non-Profit research organisation Institute of Bioinformatics (IOB), Bangalore, India. This database is a collaborative output of IOB and the Pandey Lab of Johns Hopkins University. Overview The HPRD is a result of an international collaborative effort between the Institute of Bioinformatics in Bangalore, India and the Pandey lab at Johns Hopkins University in Baltimore, USA. HPRD contains manually curated scientific information pertaining to the biology of most human proteins. Information regarding proteins involved in human diseases is annotated and linked to Online Mendelian Inheritance in Man (OMIM) database. The National Center for Biotechnology Information provides link to HPRD through its human protein databases (e.g. Entrez Gene, RefSeq protein pertaining to genes and proteins. This resource depicts information on human ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BioCyc Database Collection
The BioCyc database collection is an assortment of organism specific Pathway/Genome Databases (PGDBs) that provide reference to genome and metabolic pathway information for thousands of organisms. As of July 2023, there were over 20,040 databases within BioCyc. SRI International, of the based in Menlo Park, California, maintains the BioCyc database family. Categories of Databases Based on the manual curation done, BioCyc database family is divided into 3 tiers: Tier 1: Databases which have received at least one year of literature based manual curation. Currently there are seven databases in Tier 1. Out of the seven, |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. This multifaceted research domain necessitates the collaborative efforts of chemists, biologists, mathematicians, physicists, and engineers to decipher the biology of intricate living systems by merging various quantitative molecular measurements with carefully constructed mathematical models. It represents a comprehensive method for comprehending the complex relationships within biological systems. In contrast to conventional biological studies that typically center on isolated elements, systems biology seeks to combine different biological data to create models that illustrate and elucidate the dynamic interactions with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
