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Bifurcated Needle
The bifurcated needle is a narrow steel rod, approximately long with two prongs at one end. It was designed to hold one dose of reconstituted freeze-dried smallpox vaccine between its prongs. Up to one hundred vaccinations can be given from one vial of the reconstituted vaccine. The established technique for smallpox vaccination is to dip the needle in the vaccine, and then perpendicularly puncture a person's upper arm fifteen times rapidly in a small circular area. Though skin in the area should be clean, use of an alcohol swab is optional and if used the skin must be allowed to fully dry to avoid deactivation of the live virus vaccine. The punctures should remain in an area approximately 5 mm in diameter. The needle is then disposed of. When done correctly a trace of blood appears at the vaccination site within 10 to 20 seconds after the procedure. The bifurcated needle was created as a more efficient and cost effective alternative to the jet injector previously in use. It was ...
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Smallpox Vaccine Injection
Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus ''Orthopoxvirus''. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated to date. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was transmitted from one person to another primarily through prolonged face-to-face contact with an infected person or rarely via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medications could potentially ...
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US Navy 030305-N-3235P-513 A Hospital Corpsman Dips A Bifurcated Vaccinating Needle Into An Open Vial Of Small Pox Vaccine
US or Us most often refers to: * ''Us'' (pronoun), the objective case of the English first-person plural pronoun ''we'' * US, an abbreviation for the United States US, U.S., Us, us, or u.s. may also refer to: Arts and entertainment Albums * ''Us'' (Brother Ali album) or the title song, 2009 * ''Us'' (Empress Of album), 2018 * ''Us'' (Mull Historical Society album), 2003 * ''Us'' (Peter Gabriel album), 1992 * ''Us'' (EP), by Moon Jong-up, 2021 * ''Us'', by Maceo Parker, 1974 * ''Us'', mini-album by Peakboy, 2019 Songs * "Us" (James Bay song), 2018 * "Us" (Jennifer Lopez song), 2018 * "Us" (Regina Spektor song), 2004 * "Us" (Gracie Abrams song), 2024 * "Us", by Azealia Banks from '' Fantasea'', 2012 * "Us", by Celine Dion from ''Let's Talk About Love'', 1997 * "Us", by Gucci Mane from '' Delusions of Grandeur'', 2019 * "Us", by Spoon from '' Hot Thoughts'', 2017 Other media * US Festival, two 1980s California music festivals organized by Steve Wozniak * ''Us'' (1991 ...
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Smallpox Vaccine
The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the 20th century. From 1958 to 1977, the World Health Organization (WHO) conducted a global vaccination campaign that eradicated smallpox, making it the only human disease to be eradicated. Although routine smallpox vaccination is no longer performed on the general public, the vaccine is still being produced for research, and to guard against bioterrorism, biological warfare, and mpox.Anderson MG, Frenkel LD, Homann S, and Guffey J. (2003), "A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values"; ''Pediatr Infect Dis ...
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Jet Injector
A jet injector is a type of medical injecting syringe device used for a method of drug delivery known as jet injection. A narrow, high-pressure stream of liquid is made to penetrate the outermost layer of the skin (stratum corneum) to deliver medication to targeted underlying tissues of the epidermis or dermis ("cutaneous" injection, also known as classical "intradermal" injection), fat ("subcutaneous" injection), or muscle ("intramuscular" injection). The jet stream is usually generated by the pressure of a piston in an enclosed liquid-filled chamber. The piston is usually pushed by the release of a compressed metal spring, although devices being studied may use piezoelectric effects and other novel technologies to pressurize the liquid in the chamber. The springs of currently marketed and historical devices may be compressed by operator muscle power, hydraulic fluid, built-in battery-operated motors, compressed air or gas, and other means. Gas-powered and hydraulically powered ...
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Benjamin Rubin
Benjamin Rubin (September 27, 1917 in New York, New York – March 8, 2010) was an American microbiologist, known as the inventor of the bifurcated vaccination needle, which played an important role in the eradication of smallpox Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus '' Orthopoxvirus''. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (W .... Rubin invented this device by taking the eyelet of a sewing machine needle and grinding it down. In 1992, Rubin was inducted into the National Inventors Hall of Fame. References 1917 births 2010 deaths American microbiologists Jewish American scientists American vaccinologists 21st-century American Jews {{US-biologist-stub ...
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World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has 6 regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level. The WHO's purpose is to achieve the highest possible level of health for all the world's people, defining health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." The main functions of the World Health Organization include promoting the control of epidemic and endemic diseases; providing and improving the teaching and training in public health, the medical treatment of disease, and related matters; and promoting the establishment of international standards for biologic ...
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Drug Delivery Devices
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders. Classification Pharmaceutical drugs are often classified into drug classes—groups of related drugs that have s ...
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Smallpox Eradication
Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus ''Orthopoxvirus''. The Ali Maow Maalin#Maalin's case, last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the Eradication of infectious diseases, global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated to date. The initial symptoms of the disease included fever and vomiting. This was followed by formation of Ulcer (dermatology), ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then Wound healing#Proliferative phase, scabbed over and fell off, leaving scars. The disease was transmitted from one person to another primarily through prolonged face-to-face contact with an infected person or rarely via Fomite, contaminated objects. Prevention was ...
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