HOME



picture info

Berberine Hydrochloride
Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids, occurring naturally as a secondary metabolite in some plants including species of ''Berberis'', from which its name is derived. Due to their yellow pigmentation, raw ''Berberis'' materials were once commonly used to dye wool, leather, and wood. Under ultraviolet light, berberine shows a strong yellow fluorescence, making it useful in histology for staining heparin in mast cells. As a natural dye, berberine has a color index of 75160. Biological sources The following plants are biological sources of berberine: * ''Berberis vulgaris'' (barberry) * ''Berberis aristata'' (tree turmeric) * ''Berberis thunbergii'' * ''Fibraurea tinctoria'' * ''Mahonia aquifolium'' (Oregon grape) * ''Hydrastis canadensis'' (goldenseal) * '' Xanthorhiza simplicissima'' (yellowroot) * ''Phellodendron amurense'' (Amur cork tree) * ''Coptis chinensis'' (Chinese goldthread) * ''Tinospora cordifolia'' * ''Ar ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

The Merck Index
''The Merck Index'' is an encyclopedia of chemicals, drugs and biologicals with over 10,000 monographs on single substances or groups of related compounds published online by the Royal Society of Chemistry. History The first edition of the Merck's Index was published in 1889 by the German chemical company Emanuel Merck and was primarily used as a sales catalog for Merck's growing list of chemicals it sold. The American subsidiary was established two years later and continued to publish it. During World War I the US government seized Merck's US operations and made it a separate American "Merck" company that continued to publish the Merck Index. In 2012 the Merck Index was licensed to the Royal Society of Chemistry. An online version of The Merck Index, including historic records and new updates not in the print edition, is commonly available through research libraries. It also includes an appendix with monographs on organic named reactions. The 15th edition was published in A ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Fibraurea Tinctoria
''Fibraurea tinctoria'' is a species of flowering plant native to South Asia, where it grows in wet tropical areas between India and the Philippines. It is considered locally common. It fruits in April and May, producing yellow-orange drupes. Common names for this plant include yellow root (East Kalimantan), ''akar palo'' (Aceh), and ''akar kuning'' (Central Kalimantan). Research The plant is used in Indonesian traditional medicine, primarily because it contains berberine, an isoquinoline alkaloid under preliminary research to identify its possible properties. During a Field research, field observation, a male Sumatran orangutan, known to researchers as Rakus, chewed vine leaves and applied the masticated plant material to an open wound on his face. According to Primatology, primatologists who had been observing Rakus at a nature preserve, "Five days later the facial wound was closed, while within a few weeks it had healed, leaving only a small scar." References External lin ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Tetracyclic
Tetracyclics are cyclic compound, cyclic chemical compounds that contain four fused ring (chemistry), rings of atoms, for example, Tröger's base. Some tricyclic compounds having three fused and one tethered ring (connected to main nucleus by a single bond) can also classified as tetracyclic, for example, ciclazindol. Tetracyclic compounds have various pharmaceutical drug, pharmaceutical uses, such as: *tetracycline antibiotics **Doxycycline **Tigecycline **Omadacycline **Eravacycline *tetracyclic antidepressants **Benzoctamine **Loxapine **Mazindol **Mianserin **Mirtazapine See also * Tricyclic * Heterocyclic References

{{Tetracyclics Tetracyclic compounds, ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Biosynthesis Of Berberine
Biosynthesis, i.e., chemical synthesis occurring in biological contexts, is a term most often referring to multi-step, enzyme- catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products. Examples of biosynthetic pathways include those for the production of amino acids, lipid membrane components, and nucleotides, but also for the production of all classes of biological macromolecules, and of acetyl-coenzyme A, adenosine triphosphate, nicotinamide adenine dinucleotide and other key intermediate and transactional molecules needed for metabolism. Thus, in biosynthesis, any of an array of compounds, from simple to complex, are converted into other compounds, and so it includes both the catabolism and anabolism (building up and breaking down) of complex molecules (including macromolecules). Biosynthetic processes are ofte ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Rhizome
In botany and dendrology, a rhizome ( ) is a modified subterranean plant stem that sends out roots and Shoot (botany), shoots from its Node (botany), nodes. Rhizomes are also called creeping rootstalks or just rootstalks. Rhizomes develop from axillary buds and grow horizontally. The rhizome also retains the ability to allow new shoots to grow upwards. A rhizome is the main stem of the plant that runs typically underground and horizontally to the soil surface. Rhizomes have nodes and internodes and auxiliary buds. Roots do not have nodes and internodes and have a root cap terminating their ends. In general, rhizomes have short internodes, send out roots from the bottom of the nodes, and generate new upward-growing shoots from the top of the nodes. A stolon is similar to a rhizome, but stolon sprouts from an existing stem having long internodes and generating new shoots at the ends, they are often also called runners such as in the strawberry plant. A stem tuber is a thickene ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Eschscholzia Californica
''Eschscholzia californica'', the California poppy, golden poppy, Mexican poppy, California sunlight or cup of gold, is a species of flowering plant in the family Papaveraceae, native to the United States and Mexico. It is cultivated as an ornamental plant flowering in summer (spring in southern Australia), with showy flowers in brilliant shades of red, orange and yellow (occasionally pink and white). It is also used as food or a garnish. It had various uses in indigenous herbalism. It became the official state flower of California in 1903. Description California poppy is a perennial or annual plant growing to tall with alternately branching glaucous blue-green foliage. The leaves are alternately divided into round, lobed segments. The flowers are solitary on long stems, silky-textured, with four petals, each petal long and broad; flower color ranges through yellow, orange and red. Flowering occurs from February to September in the northern hemisphere. The petals close a ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Argemone Mexicana
''Argemone mexicana'', also known by the common names Mexican poppy, Mexican prickly poppy, flowering thistle, cardo, and cardosanto, is a species of poppy found in Mexico and now widely naturalized in many parts of the world. An extremely hardy pioneer plant, it is tolerant of drought and poor soil, often being the only cover on new road cuttings or verges. It has bright yellow latex. It is poisonous to grazing animals, and it is rarely eaten, but it has been used medicinally by many peoples, including those in its native area, as well as the indigenous peoples of the western United States, parts of Mexico, and many parts of India. In India, during the colorful festival Holika Dahan, adults and children worship by offering flowers, and this species is in its maximum flowering phase during March when the Holi festival is celebrated. It is also referred to as "kateli ka phool" in India. Chemical constituents ''Argemone mexicana'' seeds contain 22–36% of a pale yellow non- ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Tinospora Cordifolia
''Tinospora cordifolia'', the heart-leaved moonseed, is a herbaceous vine of the family Menispermaceae native to South and Southeast Asia. It has been used in Ayurveda in an attempt to treat various disorders. There is no good evidence ''Tinospora cordifolia'' is of benefit as a medicine and its use can lead to potentially fatall herb-induced liver injury. Botanical description It is a large, deciduous, extensively-spreading, climbing vine with several elongated twining branches. Leaves are simple, alternate, and exstipulate with long petioles up to long which are roundish and pulvinate, both at the base and apex with the basal one longer and twisted partially and half way around. It gets its name ''heart-leaved moonseed'' by its heart-shaped leaves and its reddish fruit. Lamina are broadly ovate or ovate cordate, long or broad, seven nerved and deeply cordate at base, membranous, pubescent above, whitish tomentose with a prominent reticulum beneath. Flowers are unisexual, ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Coptis Chinensis
''Coptis chinensis'', the Chinese goldthread, is a species of goldthread flowering plant native to China. Etymology *''Coptis chinensis'' Franch. var. ''chinensis''''Coptis chinensis''
in BoDD – Botanical Dermatology Database
**(syn. ''Coptis teeta'' Wallich var. ''chinensis'')


Chemical constituents

The of ''Coptis chinensis'' contain the isoquinoline alkaloids

picture info

Phellodendron Amurense
''Phellodendron amurense'' is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of ''huáng bò'' ( or wiktionary:黄, 黄wiktionary:檗, 檗), one of the 50 fundamental herbs used in traditional Chinese medicine. The Ainu people used its fruit, called "shikerebe-ni" (in Ainu language, Ainu, ''sikerpe''), as a painkiller. It is known as ''hwangbyeok'' in Korean and (キハダ) ''kihada'' in Japanese. It is native to eastern Asia: northern China, northeast China, Korea, Ussuri, Amur Oblast, Amur, and Japan, the Amur cork tree is considered invasive in many parts of North America. The State of Massachusetts lists it as a noxious weed.Bruce Marlin''Phellodendron amurense''/ref> Medicinal use It has been used as a Chinese traditional medicine for the treatment of meningitis, bacillary dysentery, pneumonia, tuberculosis, tumours, jaundice and liver cirrhosis. Used orally to treat abdominal pain, diarrhea, gastroenteritis and urinary ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]