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Aspermia
Aspermia is the complete lack of semen with ejaculation (not to be confused with azoospermia, the lack of sperm cells in the semen). It is associated with infertility. One of the causes of aspermia is retrograde ejaculation, because of that the sperm is kept into the bladder and the final ejaculate is 0 mL. It can be brought on by excessive drug use, or as a result of prostate surgery. It can also be caused by alpha blockers such as tamsulosin and silodosin. Another cause of aspermia is ejaculatory duct obstruction, which may result in a complete lack or a very low-concentration of semen ( oligospermia), in which the semen contains only the secretion of accessory prostate glands downstream to the orifice of the ejaculatory ducts. Aspermia can be caused by androgen deficiency. This can be the result of absence of puberty, in which the prostate gland and seminal vesicles (which are the main sources of semen) remain small due to lack of androgen exposure and do not produce ...
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Ejaculatory Duct Obstruction
Ejaculatory duct obstruction (EDO) is a pathological condition which is characterized by the obstruction of one or both ejaculatory ducts. Thus, the efflux of (most constituents of) semen is not possible. It can be congenital or acquired. It is a cause of male infertility and/or pelvic pain. Ejaculatory duct obstruction must not be confused with an obstruction of the vas deferens. Cause If both ejaculatory ducts are completely obstructed, affected men will demonstrate male infertility due to aspermia/ azoospermia. They will suffer from a very low volume of semen which lacks the gel-like fluid of the seminal vesicles or from no semen at all while they are able to have the sensation of an orgasm during which they will have involuntary contractions of the pelvic musculature. This is contrary to some other forms of anejaculation. In addition, it is reported to be a cause for pelvic pain, especially shortly after ejaculation. In case of proven fertility but unresolved pelvic pain, ...
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Retrograde Ejaculation
Retrograde ejaculation occurs when semen which would be ejaculated via the urethra is redirected to the urinary bladder. Normally, the sphincter of the bladder contracts before ejaculation, inhibiting urination and preventing a reflux of semen into the bladder. The semen is forced to exit via the urethra, the path of least resistance. When the bladder sphincter does not function properly, retrograde ejaculation may occur. It can also be induced deliberately as a primitive form of male birth control (known as ''coitus saxonicus'') or as part of certain alternative medicine practices. The retrograde-ejaculated semen is excreted from the bladder during the next urination. Signs and symptoms Retrograde ejaculation is sometimes referred to as a " dry orgasm." A man may notice that no semen is produced during masturbation despite the occurrence of orgasm. Another underlying cause for this phenomenon may be ejaculatory duct obstruction. During a male orgasm, sperm are released fro ...
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Ejaculatory Ducts
The ejaculatory ducts (''ductus ejaculatorii'') are paired structures in the male reproductive system. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and open into the urethra above the seminal colliculus. During ejaculation, semen passes through the prostate gland, enters the urethra and exits the body via the urinary meatus. Function Ejaculation Ejaculation occurs in two stages, the emission stage and the expulsion stage.Rathus, S. A., Nevid, J. S., Fichner-Rathus, L., Herold, E. S. (2010). ''Human Sexuality in a World of Diversity''. Pearsons Education Canada, Pearson Canada Inc. Toronto, ON. The emission stage involves the workings of several structures of the ejaculatory duct; contractions of the prostate gland, the seminal vesicles, the bulbourethral gland and the vas deferens push fluids into the prostatic urethra. The semen is stored here until ejaculation occurs. Muscles at the base ...
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Retrograde Ejaculation
Retrograde ejaculation occurs when semen which would be ejaculated via the urethra is redirected to the urinary bladder. Normally, the sphincter of the bladder contracts before ejaculation, inhibiting urination and preventing a reflux of semen into the bladder. The semen is forced to exit via the urethra, the path of least resistance. When the bladder sphincter does not function properly, retrograde ejaculation may occur. It can also be induced deliberately as a primitive form of male birth control (known as ''coitus saxonicus'') or as part of certain alternative medicine practices. The retrograde-ejaculated semen is excreted from the bladder during the next urination. Signs and symptoms Retrograde ejaculation is sometimes referred to as a " dry orgasm." A man may notice that no semen is produced during masturbation despite the occurrence of orgasm. Another underlying cause for this phenomenon may be ejaculatory duct obstruction. During a male orgasm, sperm are released fro ...
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Azoospermia
Azoospermia is the medical condition of a man whose semen contains no sperm. It is associated with male infertility, but many forms are amenable to medical treatment. In humans, azoospermia affects about 1% of the male population and may be seen in up to 20% of male infertility situations in Canada. In a non-pathological context, azoospermia is also the intended result of a vasectomy. Classification Azoospermia can be classified into three major types. Many conditions listed may also cause various degrees of oligospermia rather than azoospermia. Pretesticular and testicular azoospermia are known as non-obstructive azoospermia, whereas post-testicular azoospermia is considered obstructive. Pretesticular Inadequate stimulation of normal testicles and the genital tract characterizes pretesticular azoospermia. Typically, follicle-stimulating hormone (FSH) levels are low (hypogonadotropic), commensurate with inadequate stimulation of the testes to produce sperm. Examples include ...
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Androgen Deficiency
Androgen deficiency is a medical condition characterized by insufficient androgenic activity in the body. Androgen deficiency most commonly affects women, and is also called Female androgen insufficiency syndrome (FAIS), although it can happen in both sexes. Androgenic activity is mediated by androgens (a class of steroid hormones with varying affinities for the androgen receptor), and is dependent on various factors including androgen receptor abundance, sensitivity and function. Androgen deficiency is associated with lack of energy and motivation, depression, lack of desire (libido), and in more severe cases changes in secondary sex characteristics. Signs and symptoms Symptoms of the condition in males consist of loss of libido, impotence, infertility, shrinkage of the testicles, penis, and prostate, diminished masculinization (e.g., decreased facial and body hair growth), low muscle mass, anxiety, depression, fatigue, vasomotor symptoms (hot flashes), insomnia, headaches, ca ...
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Ejaculation
Ejaculation is the discharge of semen (the ''ejaculate''; normally containing sperm) from the penis through the urethra. It is the final stage and natural objective of male sexual stimulation, and an essential component of natural conception. After forming an erection, many men emit Pre-ejaculate, pre-ejaculatory fluid during stimulation prior to ejaculating. Ejaculation involves involuntary Muscle contraction, contractions of the pelvic floor and is normally linked with orgasm. It is a normal part of male Puberty, human sexual development. Ejaculation can occur spontaneously during sleep (a nocturnal emission or "wet dream") or in rare cases because of prostate, prostatic disease. ''Anejaculation'' is the condition of being unable to ejaculate. ''Painful ejaculation, Dysejaculation'' is an ejaculation that is painful or uncomfortable. Retrograde ejaculation is the backward flow of semen from the urethra into the urinary bladder, bladder. Premature ejaculation happens shortly ...
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Maximal Androgen Blockade
Maximum or maximal androgen blockade (MAB) or complete or combined androgen blockade (CAB) is a medical treatment involving the combination of both androgen receptor (AR) antagonism and inhibition or suppression of androgen production to attain maximal effectiveness in androgen deprivation therapy (ADT). An example of MAB is the combination of bicalutamide, an AR antagonist, with a gonadotropin-releasing hormone (GnRH) analogue such as leuprorelin or cetrorelix. MAB was developed for and is employed in the treatment of prostate cancer. Triple androgen blockade (TrAB) is a method of ADT in which a 5α-reductase inhibitor such as finasteride or dutasteride is added to CAB. MAB has been found to produce higher rates of gynecomastia (7 to 28%) than orchiectomy and GnRH analogues alone (1 to 16%), but lower rates than nonsteroidal antiandrogen monotherapy such as with bicalutamide Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is ...
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Prostate Cancer
Prostate cancer is the neoplasm, uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of the prostate tissue is usually detected through Screening (medicine), screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels. Those with high levels of PSA in their blood are at increased risk for developing prostate cancer. Diagnosis requires a prostate biopsy, biopsy of the prostate. If cancer is present, the pathologist assigns a Gleason score; a higher score represents a more dangerous tumor. Medical imaging is performed to look for cancer that has spread outside the prostate. Based on the Gleason score, PSA levels, and imaging results, a cancer case is assigned a cancer staging, stage 1 to 4. A higher stage signifies a more advanced, more dangerous disease. Most prostate tumors remain small and cause no health problems. These are managed with active surveillance of prostate cancer, ...
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Seminal Vesicles
The seminal vesicles (also called vesicular glands or seminal glands) are a pair of convoluted tubular accessory glands that lie behind the urinary bladder of male mammals. They secrete fluid that largely composes the semen. The vesicles are 5–10 cm in size, 3–5 cm in diameter, and are located between the bladder and the rectum. They have multiple outpouchings, which contain secretory glands, which join together with the vasa deferentia at the ejaculatory ducts. They receive blood from the vesiculodeferential artery, and drain into the vesiculodeferential veins. The glands are lined with column-shaped and cuboidal cells. The vesicles are present in many groups of mammals, but not marsupials, monotremes or carnivores. Inflammation of the seminal vesicles is called seminal vesiculitis and most often is due to bacterial infection as a result of a sexually transmitted infection or following a surgical procedure. Seminal vesiculitis can cause pain in the lower abdo ...
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Prostate Gland
The prostate is an male accessory gland, accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found in all male mammals. It differs between species anatomically, chemically, and physiologically. Anatomically, the prostate is found below the bladder, with the urethra passing through it. It is described in gross anatomy as consisting of lobes and in microanatomy by zone. It is surrounded by an elastic, fibromuscular capsule and contains glandular tissue, as well as connective tissue. The prostate produces and contains fluid that forms part of semen, the substance emitted during ejaculation as part of the male human sexual response cycle, sexual response. This prostatic fluid is slightly Alkalinity, alkaline, milky or white in appearance. The alkalinity of semen helps neutralize the acidity of the vagina, vaginal tract, prolonging the lifespan of sperm. The prostatic fluid is expelled in the first part of ej ...
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