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Arterial Blood
Arterial blood is the oxygenated blood in the circulatory system found in the pulmonary vein, the left chambers of the heart, and in the artery, arteries. It is bright red in color, while venous blood is dark red in color (but looks purple through the translucent skin). It is the contralateral term to venous blood. Framed in the cardiac cycle, often historically accredited to the Wiggers diagram, arterial blood has just passed through the lungs and is ready to boost oxygen to sustain the peripheral organs. The essential difference between venous and arterial blood is the curve of the oxygen saturation of haemoglobin. The difference in the oxygen content of the blood between the arterial blood and the venous blood is known as the arteriovenous oxygen difference. See also * Acidosis * Alkalosis * Arterial blood gas * Chemical equilibrium * Oxygen saturation * pH#Living systems, pH * pKa References

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Arterial Blood Gas
An arterial blood gas (ABG) test, or arterial blood gas analysis (ABGA) measures the amounts of arterial gases, such as oxygen and carbon dioxide. An ABG test requires that a small volume of blood be drawn from the radial artery with a syringe and a thin needle, but sometimes the femoral artery in the groin or another site is used. The blood can also be drawn from an arterial catheter. An ABG test measures the blood gas tension values of the arterial partial pressure of oxygen (PaO2), and the arterial partial pressure of carbon dioxide (PaCO2), and the blood's pH. In addition, the arterial oxygen saturation (SaO2) can be determined. Such information is vital when caring for patients with critical illnesses or respiratory disease. Therefore, the ABG test is one of the most common tests performed on patients in intensive-care units. In other levels of care, pulse oximetry plus transcutaneous carbon-dioxide measurement is a less invasive, alternative method of obtaining simila ...
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Venous And Arterial Blood
Veins () are blood vessels in the circulatory system of humans and most other animals that carry blood towards the heart. Most veins carry deoxygenated blood from the tissues back to the heart; exceptions are those of the pulmonary and fetal circulations which carry oxygenated blood to the heart. In the systemic circulation In vertebrates, the circulatory system is a organ system, system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of ..., Artery, arteries carry oxygenated blood away from the heart, and veins return deoxygenated blood to the heart, in the deep veins. There are three sizes of veins: large, medium, and small. Smaller veins are called venules, and the smallest the post-capillary venules are microscopic that make up the veins of the microcirculation. Veins are often closer to the skin than arteries. Veins have less smooth muscle a ...
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Haemoglobin
Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12to 20grams of hemoglobin in every 100mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin. In mammals, hemoglobin makes up about 96% of a red blood cell's dry weight (excluding water), and around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL of O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. The mammalian hemoglobin molecule can bind and transport up to four oxygen ...
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Oxygen Saturation
Oxygen saturation (symbol SO2) is a relative measure of the concentration of oxygen that is Dissolution (chemistry), dissolved or carried in a given medium as a proportion of the maximal concentration that can be dissolved in that medium at the given temperature. It can be measured with a dissolved oxygen probe such as an oxygen sensor or an optode in liquid media, usually water. The standard unit of oxygen saturation is percent (%). Oxygen saturation can be measured regionally and noninvasively. Artery, Arterial oxygen saturation (SaO2) is commonly measured using pulse oximetry. Tissue saturation at peripheral scale can be measured using near-infrared spectroscopy, NIRS. This technique can be applied on both muscle and brain. In medicine In medicine, oxygen saturation refers to ''oxygenation'', or when oxygen molecules () enter the Tissue (biology), tissues of the body. In this case blood is oxygenated in the lungs, where oxygen molecules travel from the air into the blood. O ...
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Chemical Equilibrium
In a chemical reaction, chemical equilibrium is the state in which both the Reagent, reactants and Product (chemistry), products are present in concentrations which have no further tendency to change with time, so that there is no observable change in the properties of the Thermodynamic system, system. This state results when the forward reaction proceeds at the same rate as the Reversible reaction, reverse reaction. The reaction rates of the forward and backward reactions are generally not zero, but they are equal. Thus, there are no net changes in the concentrations of the reactants and products. Such a state is known as dynamic equilibrium. It is the subject of study of ''equilibrium chemistry''. Historical introduction The Concept learning, concept of chemical equilibrium was developed in 1803, after Claude Louis Berthollet, Berthollet found that some chemical reactions are Reversible reaction, reversible. For any reaction mixture to exist at equilibrium, the reaction rate, ...
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Alkalosis
Alkalosis is the result of a process reducing hydrogen ion concentration of arterial blood plasma (alkalemia). In contrast to acidemia (serum pH 7.35 or lower), alkalemia occurs when the serum pH is higher than normal (7.45 or higher). Alkalosis is usually divided into the categories of respiratory alkalosis and metabolic alkalosis or a combined respiratory/metabolic alkalosis. Signs and symptoms Metabolic alkalosis is usually accompanied by low blood potassium concentration, causing, e.g., muscular weakness, muscle pain, and muscle cramps (from disturbed function of the skeletal muscles), and muscle spasms (from disturbed function of smooth muscles). It may also cause low blood calcium concentration. As the blood pH increases, blood transport proteins, such as albumin, become more ionized into anions. This causes the free calcium present in blood to bind more strongly with albumin. If severe, it may cause tetany. Causes Respiratory alkalosis is caused by hyperventilati ...
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Acidosis
Acidosis is a biological process producing hydrogen ions and increasing their concentration in blood or body fluids. pH is the negative log of hydrogen ion concentration and so it is decreased by a process of acidosis. Acidemia The term acidemia describes the state of low blood pH, when arterial pH falls below 7.35 (except in the fetus – see below) while ''acidosis'' is used to describe the processes leading to these states. The use of acidosis for a low pH creates an ambiguity in its meaning. The difference is important where a patient has factors causing both acidosis and alkalosis, wherein the relative severity of both determines whether the result is a high, low, or normal pH. Alkalemia occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to separate the main causes. In certain situations the main cause is clear. For instance, a diabetic with ketoacidosis is a recognizable case where the main cause of acidemia is essentially obvious. ...
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Arteriovenous Oxygen Difference
The arteriovenous oxygen difference, or a-vO2 diff, is the difference in the oxygen content of the blood between the arterial blood and the venous blood. It is an indication of how much oxygen is removed from the blood in capillaries as the blood circulates in the body. The a-vO2 diff and cardiac output are the main factors that allow variation in the body's total oxygen consumption, and are important in measuring VO2. The a-vO2 diff is usually measured in millilitres of oxygen per 100 millilitres of blood (mL/100 mL).Malpeli, ''Physical Education'', Chapter 4: Acute Responses to Exercise, p. 106. Measurement The arteriovenous oxygen difference is usually taken by comparing the difference in the oxygen concentration of oxygenated blood in the femoral, brachial, or radial artery and the oxygen concentration in the deoxygenated blood from the mixed supply found in the pulmonary artery (as an indicator of the typical mixed venous supply). Put in simple terms: :''a''-''v''O2 dif ...
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Oxygen
Oxygen is a chemical element; it has chemical symbol, symbol O and atomic number 8. It is a member of the chalcogen group (periodic table), group in the periodic table, a highly reactivity (chemistry), reactive nonmetal (chemistry), nonmetal, and a potent oxidizing agent that readily forms oxides with most elements as well as with other chemical compound, compounds. Oxygen is abundance of elements in Earth's crust, the most abundant element in Earth's crust, making up almost half of the Earth's crust in the form of various oxides such as water, carbon dioxide, iron oxides and silicates.Atkins, P.; Jones, L.; Laverman, L. (2016).''Chemical Principles'', 7th edition. Freeman. It is abundance of chemical elements, the third-most abundant element in the universe after hydrogen and helium. At standard temperature and pressure, two oxygen atoms will chemical bond, bind covalent bond, covalently to form dioxygen, a colorless and odorless diatomic gas with the chemical formula ...
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Circulatory System
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek meaning ''heart'', and Latin meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Many invertebrates such as arthropods have an open circulatory system with a he ...
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Wiggers Diagram
A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century. In the Wiggers diagram, the X-axis is used to plot time subdivided into the cardiac phases, while the Y-axis typically contains the following on a single grid: * Blood pressure ** Aortic pressure ** Ventricular pressure ** Atrial pressure * Ventricular volume * Electrocardiogram * Arterial flow (optional) * Heart sounds (optional) The Wiggers diagram clearly illustrates the coordinated variation of these values as the heart beats, assisting one in understanding the entire cardiac cycle. Events Note that during isovolumetric/isovolumic contraction and relaxation, all the heart valves are closed; at no time are all the heart valves open. *S3 and S4 heart sounds are associated with pathologies and are not routinely heard. Additional images File:Heart systole.svg, Ventricular systole File:Heart diasystole.svg, Cardia ...
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Cardiac Cycle
The cardiac cycle is the performance of the heart, human heart from the beginning of one heartbeat to the beginning of the next. It consists of two periods: one during which the heart muscle relaxes and refills with blood, called diastole, following a period of robust contraction and pumping of blood, called systole. After emptying, the heart relaxes and expands to receive another influx of blood returning from the lungs and other systems of the body, before again contracting. Assuming a healthy heart and a typical rate of 70 to 75 beats per minute, each cardiac cycle, or heartbeat, takes about 0.8 second to complete the cycle. Duration of the cardiac cycle is inversely proportional to the heart rate. Description There are two atrium (heart), atrial and two ventricle (heart), ventricle chambers of the heart; they are paired as the heart#Left heart, left heart and the heart#Right heart, right heart—that is, the left atrium with the left ventricle, the right atrium with the r ...
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