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Anal Intraepithelial Neoplasia
Intraepithelial neoplasia (IEN) is the development of a benign neoplasia or high-grade dysplasia in an epithelium. The exact dividing line between dysplasia and neoplasia has been very difficult to draw throughout the era of medical science. It varies between persons. In the localizations shown below, the term ''intraepithelial neoplasia'' is used to describe more accurately what was historically referred to as epithelial dysplasia. IEN is not cancer, but it is associated with higher risk for developing cancer in future. It is thus sometimes a precancerous condition A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. Clinically, precancerous conditions encompass a variety of abnormal tissues with an increase .... Localizations References Lesions {{oncology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anus AIN HighGrade MP PA
In mammals, invertebrates and most fish, the anus (: anuses or ani; from Latin, 'ring' or 'circle') is the external body orifice at the ''exit'' end of the digestive tract (bowel), i.e. the opposite end from the mouth. Its function is to facilitate the expulsion of wastes that remain after digestion. Bowel contents that pass through the anus include the gaseous flatus and the semi-solid feces, which (depending on the type of animal) include: indigestible matter such as bones, hair pellets, endozoochorous seeds and digestive rocks; Summary at residual food material after the digestible nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; excreted metabolites like bilirubin-containing bile; and dead mucosal epithelia or excess gut bacteria and other endosymbionts. Passage of feces through the anus is typically controlled by muscular sphincters, and failure to stop unwanted passages results ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biliary Tract
The biliary tract (also biliary tree or biliary system) refers to the liver, gallbladder and bile ducts, and how they work together to make, store and secrete bile. Bile consists of water, electrolytes, bile acids, cholesterol, phospholipids and conjugated bilirubin. Some components are synthesized by hepatocytes (liver cells); the rest are extracted from the blood by the liver. Bile is secreted by the liver into small ducts that join to form the common hepatic duct. Between meals, secreted bile is stored in the gallbladder. During a meal, the bile is secreted into the duodenum (part of the small intestine) to rid the body of waste stored in the bile as well as aid in the absorption of dietary fats and oils. Structure The biliary tract refers to the path by which bile is secreted by the liver then transported to the duodenum, the first part of the small intestine. A structure common to most members of the mammal family, the biliary tract is often referred to as a tree bec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaginal Intraepithelial Neoplasia
Vaginal intraepithelial neoplasia (VAIN) is a condition that describes premalignant histological findings in the vagina characterized by dysplastic changes. The disorder is rare and generally has no symptoms. VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear). Like cervical intraepithelial neoplasia, VAIN comes in three stages, VAIN 1, 2, and 3. In VAIN 1, a third of the thickness of the cells in the vaginal skin are abnormal, while in VAIN 3, the full thickness is affected. VAIN 3 is also known as carcinoma in-situ, or stage 0 vaginal cancer.Cancer Research UK (2002)The stages of cancer of the vagina. CancerHelp UK. Retrieved January 3, 2008. Infection with certain types of the human papillomavirus ("high-risk types") may be associated with up to 80% of cases of VAIN.Cancer Research UK (2002)Risks and causes of vaginal cancer. CancerHelp UK. Retrieved January 3, 2008. Vaccinating with HPV vaccine Human papillomavirus (HPV) vacci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prostatic Intraepithelial Neoplasia
On either side of the urethral crest is a slightly depressed fossa, the prostatic sinus, the floor of which is perforated by numerous apertures, the orifices of the prostatic ducts from the lateral lobes of the prostate The prostate is an male accessory gland, accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found in all male mammals. It differs between species anatomically, chemica .... References External links * - "The Male Pelvis: The Prostate Gland" * () Prostate {{genitourinary-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Penis
In Human body, human anatomy, the penis (; : penises or penes; from the Latin ''pēnis'', initially 'tail') is an external sex organ (intromittent organ) through which males urination, urinate and ejaculation, ejaculate, as Penis, on other animals. Together with the testes and surrounding structures, the penis functions as part of the male reproductive system. The main parts of the penis are the Root of penis, root, Body of penis, body, the epithelium of the penis, including the shaft skin, and the foreskin covering the glans penis, glans. The body of the penis is made up of three columns of tissue (biology), tissue: two Corpus cavernosum penis, corpora cavernosa on the dorsal side and corpus spongiosum penis, corpus spongiosum between them on the ventral side. The Urethra#Male, urethra passes through the prostate gland, where it is joined by the ejaculatory ducts, and then through the penis. The urethra goes across the corpus spongiosum and ends at the tip of the glans as the o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pancreas
The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. Ninety-nine percent of the pancreas is exocrine and 1% is endocrine. As an endocrine gland, it functions mostly to regulate blood sugar levels, secreting the hormones insulin, glucagon, somatostatin and pancreatic polypeptide. As a part of the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum through the pancreatic duct. This juice contains bicarbonate, which neutralizes acid entering the duodenum from the stomach; and digestive enzymes, which break down carbohydrates, proteins and lipids, fats in food entering the duodenum from the stomach. Inflammation of the pancreas is kno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastrointestinal Intraepithelial Neoplasia
Gastrointestinal intraepithelial neoplasia (GIN or GIIN) is also known as gastrointestinal dysplasia. Gastrointestinal dysplasia refers to abnormal growth of the epithelial tissue lining the gastrointestinal tract including the esophagus, stomach, and colon. Pancreatic, biliary, and rectal Intraepithelial Neoplasia are discussed separately. The regions of abnormal growth are confined by the basement membrane adjacent to the epithelial tissue and are thought to represent pre-cancerous lesions. In the GI tract, tumor progression is thought to occur in a series of steps. It begins with normal tissue and long-term inflammation causes the cells to undergo atrophy, metaplasia, dysplasia, and finally, becomes an adenoma or carcinoma Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesoder .... Gi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endometrial Intraepithelial Neoplasia
Endometrial intraepithelial neoplasia (EIN) is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial cells, arising from the glands that line the uterus, which have a tendency over time to progress to the most common form of uterine cancer—endometrial adenocarcinoma, endometrioid type. History EIN lesions have been discovered by a combination of molecular, histologic, and clinical outcome studies beginning in the 1990s which provide a multifaceted characterization of this disease. They are a subset of a larger mixed group of lesions previously called "endometrial hyperplasia". The EIN diagnostic schema is intended to replace the previous " endometrial hyperplasia" classification as defined by the World Health Organization in 1994, which have been separated into benign (benign endometrial hyperplasia) and premalignant (EIN) classes in accordance with their behavior and cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervical Intraepithelial Neoplasia
Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. More specifically, CIN refers to the potentially Precancerous condition, precancerous transformation of cells of the cervix. CIN most commonly occurs at the Transformation zone, squamocolumnar junction of the cervix, a transitional area between the Squamous epithelial cell, squamous epithelium of the vagina and the columnar epithelium of the endocervix. It can also occur in vaginal walls and vulvar epithelium. CIN is graded on a 1–3 scale, with 3 being the most abnormal (see classification section below). Human papillomavirus (Human papillomavirus infection, HPV) infection is necessary for the development of CIN, but not all with this infection develop cervical cancer. Many women with HPV infection never develop CIN or cervical cancer. Typically, HPV resolves on its own. However, those with an HPV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Anus
In humans, the anus (: anuses or ani; from Latin ''ānus'', "ring", "circle") is the external opening of the rectum located inside the intergluteal cleft. Two sphincters control the exit of Human feces, feces from the body during an act of defecation, which is the primary function of the anus. These are the internal anal sphincter and the external anal sphincter, which are circular muscles that normally maintain constriction of the orifice and which relax as required by normal physiological functioning. The inner sphincter is involuntary and the outer is voluntary. Above the anus is the perineum, which is also located beneath the vulva or scrotum. In part owing to its exposure to feces, a number of medical conditions may affect the anus, such as hemorrhoids. The anus is the site of potential infections and other conditions, including cancer (see anal cancer). With anal sex, the anus can play a role in Human sexuality, sexuality. Attitudes toward anal sex vary, and it is illeg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Progression Of Pancreatic Intraepithelial Neoplasia
Progression may refer to: In mathematics: * Arithmetic progression, a sequence of numbers such that the difference between any two successive members of the sequence is a constant * Geometric progression, a sequence of numbers such that the quotient of any two successive members of the sequence is a constant * Harmonic progression (mathematics), a sequence of numbers such that their reciprocals form an arithmetic progression In music: * Chord progression, series of chords played in order ** Backdoor progression, the cadential chord progression from iv7 to I, or flat-VII7 to I in jazz music theory ** Omnibus progression, sequence of chords which effectively divides the octave into 4 equal parts ** Ragtime progression, chord progression typical of ragtime music and parlour music genres * Progression, music software for guitarists * Progression, Markus Schulz's second Artist Album, released in 2007 In other fields: * Age progression, the process of modifying a photograph of a person ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precancerous Condition
A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer. Some of the most common precancerous conditions include certain colon polyps, which can progress into colon cancer, monoclonal gammopathy of undetermined significance, which can progress into multiple myeloma or myelodysplastic syndrome. and cervical dysplasia, which can progress into cervical cancer. Bronchial premalignant lesions can progress to squamous cell carcinoma of the lung. Pathologically, precancerous tissue can range from benign neoplasias, which are tumors which don't invade neighboring normal tissues or spread to distant organs, to dysplasia, a collection of highly abnormal cells which, in some cases, has an increased risk of progressing to anaplasia and invasive cancer which is life-thr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
