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Acute Zonal Occult Outer Retinopathy
Acute zonal occult outer retinopathy (AZOOR) is an inflammatory retinopathy in the category of white dot syndromes typified by acute loss of one or more zones of outer retinal function associated with photopsia, minimal funduscopic changes and abnormal electroretinography findings.Quillen DA, Davis JB, Gottlieb JL, Blodi BA, Callanan DG, Chang TS, et al. The white dot syndromes. American Journal of Ophthalmology. 2004;137(3):538-50.Carrasco L, Ramos M, Galisteo R, Pisa D, Fresno M, Gonzalez ME. Isolation of Candida famata from a Patient with Acute Zonal Occult Outer Retinopathy. J Clin Microbiol. 2005;43(2):635-40. Relatively little is known about the condition. This retinal disease was first described by Donald Gass in 1992.Hugo R. Salcedo, MD, Koushik Tripathy, MD (AIIMS), FRCS (Glasgow) and Vinay A. Shah M.D. The disease served as a major plot point in the BBC drama ''Second Sight Extrasensory perception (ESP), also known as a sixth sense, or cryptaesthesia, is a claimed pa ...
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White Dot Syndromes
White dot syndromes are inflammatory diseases characterized by the presence of white dots on the fundus, the interior surface of the eye.
Tewari A, Elliot D. White Dot Syndromes. 2007. Emedicine from WebMD.
The majority of individuals affected with white dot syndromes are younger than fifty years of age. Some symptoms include blurred vision and visual field loss.Quillen DA, Davis JB, Gottlieb JL, Blodi BA, Callanan DG, Chang TS, et al. The white dot syndromes. American Journal of Ophthalmology. 2004;137(3):538-50. There are many theories for the etiology of white dot syndromes including infectious, viral, genetics and autoimmune. Classically recognized white dot syndromes include:Forrester JV, IOIS, Okada AA, BenEzra D. Posterior segment intraocular inflammation: guidelines. 1998:184. *
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Photopsia
Photopsia is the presence of perceived flashes of light in the Visual field, field of vision. It is most commonly associated with: * posterior vitreous detachment * migraine aura (ocular migraine / retinal migraine) * acephalgic migraine, migraine aura without headache * scintillating scotoma * retinal detachment, retinal break or detachment * occipital lobe infarction (similar to stroke, occipital stroke) * sensory deprivation (ophthalmopathic hallucinations) * Macular degeneration, age-related macular degeneration * vertebrobasilar insufficiency * optic neuritis * visual snow syndrome Vitreous shrinkage or liquefaction, which is the most common cause of photopsia, causes a pull in vitreoretinal attachments, irritating the retina and causing it to discharge electrical impulses. These impulses are interpreted by the brain as flashes. This condition has also been identified as a common initial symptom of punctate inner choroiditis (punctate inner choroiditis, PIC), a rare retinal ...
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Electroretinography
Electroretinography measures the electrical responses of various cell types in the retina, including the Photoreceptor cell, photoreceptors (rod cell, rods and cone cell, cones), inner retinal cells (Retinal bipolar cell, bipolar and amacrine cell, amacrine cells), and the Retinal ganglion cell, ganglion cells. Electrodes are placed on the surface of the cornea (DTL silver/nylon fiber string or ERG jet) or on the skin beneath the eye (sensor strips) to measure retinal responses. Retinal pigment epithelium (RPE) responses are measured with an Electrooculography, EOG test with skin-contact electrodes placed near the Canthus, canthi. During a recording, the patient's eyes are exposed to standardized stimulus (physiology), stimuli and the resulting signal is displayed showing the time course of the signal's amplitude (voltage). Signals are very small, and typically are measured in microvolts or nanovolts. The ERG is composed of electrical potentials contributed by different cell type ...
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Second Sight (TV Series)
''Second Sight'' is a British television crime drama, principally written and created by Paula Milne, that first aired on BBC One on 9 January 2000. Originally broadcast as a single two-part pilot, before being followed by a series of three two-part stories, ''Second Sight'' follows DCI Ross Tanner (Clive Owen), a maverick cop who finds out that he has a rare disease, AZOOR, which is causing him to lose his sight. Tanner's boss, Superintendent Lawson (Thomas Wheatley), little suspects that the man he named to head the elite Specialist Elite Murder Unit is losing his sight. Tanner struggles to keep his condition a secret, but soon asks himself how long can he keep solving crimes that not even the fully sighted can fathom. The series also follows Tanner's battles with his irrepressible Inspector, Catherine Tully (Claire Skinner), who urges him to tell the truth for the sake of his own health. Rebecca Egan also co-stars as Tanner's long-suffering wife, Marilyn; while Benjamin Smit ...
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