|
Witzelsucht
Witzelsucht ( "joking addiction") is a set of rare neurological symptoms characterized by a tendency to make puns, or tell inappropriate jokes or pointless stories in socially inappropriate situations. It makes one unable to read sarcasm. A less common symptom is hypersexuality, the tendency to make sexual comments at inappropriate times or situations. Patients do not understand that their behavior is abnormal; therefore, they are non-responsive to others' reactions. This disorder is most commonly seen in patients with frontal lobe damage, particularly right frontal lobe tumors or trauma. The disorder remains named in accordance with its reviewed definition by German neurologist Hermann Oppenheim, its first description as the less focused (pathologic giddiness or lunatic mood) by German neurologist Moritz Jastrowitz, was in 1888. Signs and symptoms Case studies A condition rarely diagnosed, Witzelsucht has been well documented in the recent era in at least two cases: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Foerster's Syndrome
Foerster's syndrome is the name used by Arthur Koestler in his account of the compulsive punning first describedARNMD (1940), Vol. XX, p.732, cited in Koestler by the German neurosurgeon Otfrid Foerster. In 1929, Foerster was operating on a patient suffering from a tumor in the third ventricle – a small cavity deep down in the phylogenetically ancient regions of the midbrain, adjacent to structures intimately concerned with the arousal of emotions. When the surgeon began to manipulate the tumor, affecting those sensitive structures, the (conscious) patient burst into a manic flight of puns. He exhibited typical sound associations, and with every word of the operator broke into a flight of ideas. The sound of one word swiftly echoed in the sound of the next, and all of the words had something to do with knives and butchery. This gruesome humour, Koestler noted, all came "from a man tied face down to the operating table with his skull open". See also * Witzelsucht Witzelsucht ( " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ventromedial Prefrontal Cortex
The ventromedial prefrontal cortex (vmPFC) is a part of the prefrontal cortex in the mammalian brain. The ventral medial prefrontal is located in the frontal lobe at the bottom of the cerebral hemispheres and is implicated in the processing of risk and fear, as it is critical in the regulation of amygdala activity in humans. It also plays a role in the inhibition of emotional responses, and in the process of decision-making and self-control. It is also involved in the cognitive evaluation of morality. Anatomy While the ventromedial prefrontal cortex does not have a universally agreed on demarcation, in most sources, it is equivalent to the ventromedial reward network of Öngür and Price. This network includes Brodmann area 10, Brodmann area 14, Brodmann area 25, and Brodmann area 32, as well as portions of Brodmann area 11, Brodmann area 12, and Brodmann area 13. However, not all sources agree on the boundaries of the area. Different researchers use the term ''ventromed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venlafaxine
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Studies have shown that venlafaxine improves post-traumatic stress disorder (PTSD) as a recommended first-line treatment. It may also be used for chronic neuropathic pain. It is taken orally (swallowed by mouth). It is also available as the salt venlafaxine besylate (venlafaxine benzenesulfonate monohydrate) in an extended-release formulation (Venbysi XR). Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. A meta-analysis of randomized trials in depression found an inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mood Stabilizer
A mood stabilizer is a psychiatric medication used to treat mood disorders characterized by intense and sustained mood shifts, such as bipolar disorder and the bipolar type of schizoaffective disorder. Uses Mood stabilizers are best known for the treatment of bipolar disorder, preventing mood shifts to mania (or hypomania) and depression. Mood stabilizers are also used in schizoaffective disorder when it is the bipolar type. Examples The term "mood stabilizer" does not describe a mechanism, but rather an effect. More precise terminology based on pharmacology is used to further classify these agents. Drugs commonly classed as mood stabilizers include: Mineral ; Lithium : Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar). Signs and symptoms of toxicity include nausea, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antidepressant
Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. Common side effects of antidepressants include Xerostomia, dry mouth, weight gain, dizziness, headaches, akathisia, sexual dysfunction, and emotional blunting. There is an increased risk of Suicidal ideation, suicidal thinking and Suicide, behavior when taken by children, adolescents, and young adults. Antidepressant discontinuation syndrome, Discontinuation syndrome, which resembles recurrent Depression (mood), depression in the case of the Selective serotonin reuptake inhibitor, SSRI class, may occur after stopping the intake of any antidepressant. Research regarding the effectiveness of antidepressants for depression in adults is controversial and has found both benefits and drawbacks. Meanwhile, evidence of benefit in children and adolescents is unclear, even though antidepressant use has considerably increased in children and adolescents in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gelastic Seizure
A gelastic seizure, also known as "gelastic epilepsy", is a rare type of seizure that involves a sudden burst of energy, usually in the form of laughing. This syndrome usually occurs for no obvious reason and is uncontrollable. It is slightly more common in males than females. This syndrome can go for very long periods of time without a diagnosis, as it may resemble normal laughing or crying if it occurs infrequently. It has been associated with several conditions, such as temporal and frontal lobe lesions, tumors, atrophy, tuberous sclerosis, hemangiomas, and post-infectious foci, but mainly hypothalamic hamartomas. The term "gelastic" originates from the Greek word , which means laughter. Signs and symptoms The main sign of a gelastic seizure is a sudden outburst of laughter with no apparent cause. The laughter may sound unpleasant and sardonic rather than joyful. The outburst usually lasts for less than a minute. During or shortly after a seizure, an individual might display ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudobulbar Palsy
Pseudobulbar palsy is a medical condition characterized by the inability to control facial movements (such as chewing and speaking) and caused by a variety of neurological disorders. Patients experience difficulty chewing and swallowing, have increased reflexes and spasticity in tongue and the bulbar region, and demonstrate slurred speech (which is often the initial presentation of the disorder), sometimes also demonstrating uncontrolled emotional outbursts. The condition is usually caused by the bilateral damage to corticobulbar pathways, which are upper motor neuron pathways that course from the cerebral cortex to nuclei of cranial nerves in the brain stem. Signs and symptoms Signs and symptoms of pseudobulbar palsy include: * Slow and indistinct speech * Dysphagia (difficulty in swallowing) * Small, stiff and spastic tongue * Brisk jaw jerk * Dysarthria * Labile affect * Gag reflex may be normal, exaggerated or absent * Examination may reveal upper motor neuron lesion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frontotemporal Dementia
Frontotemporal dementia (FTD), also called frontotemporal degeneration disease or frontotemporal neurocognitive disorder, encompasses several types of dementia involving the progressive degeneration of the brain's frontal lobe, frontal and temporal lobes. Men and women appear to be equally affected. FTD generally presents as a behavioral or language disorder with gradual onset. Signs and symptoms tend to appear in late adulthood, typically between the ages of 45 and 65, although it can affect people younger or older than this. There is currently no cure or approved symptomatic treatment for FTD, although some Off-label use, off-label drugs and behavioral methods are prescribed. Features of FTD were first described by Arnold Pick between 1892 and 1906. The name ''Pick's disease'' was coined in 1922. This term is now reserved only for the behavioral variant of FTD, in which characteristic Pick bodies and Pick cells are present. These were first described by Alois Alzheimer in 1911. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amygdala
The amygdala (; : amygdalae or amygdalas; also '; Latin from Greek language, Greek, , ', 'almond', 'tonsil') is a paired nucleus (neuroanatomy), nuclear complex present in the Cerebral hemisphere, cerebral hemispheres of vertebrates. It is considered part of the limbic system. In Primate, primates, it is located lateral and medial, medially within the temporal lobes. It consists of many nuclei, each made up of further subnuclei. The subdivision most commonly made is into the Basolateral amygdala, basolateral, Central nucleus of the amygdala, central, cortical, and medial nuclei together with the intercalated cells of the amygdala, intercalated cell clusters. The amygdala has a primary role in the processing of memory, decision making, decision-making, and emotions, emotional responses (including fear, anxiety, and aggression). The amygdala was first identified and named by Karl Friedrich Burdach in 1822. Structure Thirteen Nucleus (neuroanatomy), nuclei have been identif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non Sequitur (logic)
In logic and philosophical logic, philosophy, a formal fallacy is a pattern of reasoning rendered validity (logic), invalid by a flaw in its logical structure. propositional calculus, Propositional logic, for example, is concerned with the meanings of sentences and the relationships between them. It focuses on the role of logical operators, called propositional connectives, in determining whether a sentence is true. An error in the sequence will result in a deductive argument that is invalid. The argument itself could have true premises, but still have a false logical consequence, conclusion. Thus, a formal fallacy is a fallacy in which deduction goes wrong, and is no longer a logical process. This may not affect the truth of the conclusion, since validity and truth are separate in formal logic. While a logical argument is a ''non sequitur'' if, and only if, it is invalid, the term "non sequitur" typically refers to those types of invalid arguments which do not constitute formal fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theories Of Humor
Although humor is a phenomenon experienced by most humans, its exact cause is a topic of heavy debate. There are many theories of humor which attempt to explain what it is, what social functions it serves, and what would be considered humorous. Although various classical theories of humor and laughter may be found, in contemporary academic literature, three theories of humor appear repeatedly: relief theory, superiority theory, and incongruity theory. Among current humor researchers, there is yet no consensus about which of these three theories of humor is most viable, though the incongruity theory is very often considered the most dominant. Some proponents of each of these most commonly known theories originally claimed that theirs and theirs alone explained all humor. There is, however, consensus that these theories, especially incongruity, have been building blocks for some later ones. Many theorists also now hold that the three main theories are of narrower focus than origin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
