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Vascular Closure Device
Vascular closure devices (VCDs) are medical devices used to achieve hemostasis of the small hole in the artery after a cardiovascular procedure of endovascular surgery requiring a catheterization. Cardiovascular procedures requiring catheterization include diagnostic procedures that help diagnose diseased blood vessels and interventional procedures such as angioplasty, the placement of a stent and coronary thrombectomy. During such procedures, a small incision is made in the groin area and a hole is created in the femoral artery to gain access to the artery. This hole is referred to as the access site or puncture site. At the completion of the procedure, the hole needs to be closed. Metal clip-based and suture-based VCDs may reduce time to hemostasis when compared with extrinsic (manual or mechanical) compression. However, no type of VCD has been shown to be more effective or safe than another. Goals The main goal of a vascular closure device is to provide rapid hemostasis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemostasis
In biology, hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage). It is the first stage of wound healing. Hemostasis involves three major steps: * vasoconstriction * temporary blockage of a hole in a damaged blood vessel by a platelet plug * blood coagulation (formation of fibrin clots) Coagulation, the changing of blood from a liquid to a gel which forms the fibrin clots, is essential to hemostasis. Intact blood vessels moderate blood's tendency to form clots. The endothelial cells of intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin, and prevent platelet aggregation with nitric oxide and prostacyclin. When endothelium of a blood vessel is damaged, the endothelial cells stop secretion of coagulation and aggregation inhibitors and instead secrete von Willebrand factor, which initiates the maintenance of hemostasis after in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgical Suture
A surgical suture, also known as a stitch or stitches, is a medical device used to hold Tissue (biology), body tissues together and approximate wound edges after an injury or surgery. Application generally involves using a Sewing needle, needle with an attached length of thread (yarn), thread. There are numerous types of suture which differ by needle shape and size as well as thread material and characteristics. Selection of surgical suture should be determined by the characteristics and location of the wound or the specific body tissues being approximated. In selecting the needle, thread, and suturing technique to use for a specific patient, a medical care provider must consider the tensile strength of the specific suture thread needed to efficiently hold the tissues together depending on the mechanical and shear forces acting on the wound as well as the thickness of the tissue being approximated. One must also consider the elasticity of the thread and ability to adapt to differe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Implants (medicine)
Implant can refer to: Medicine *Implant (medicine), or specifically: ** Brain implant **Breast implant ** Buttock implant **Cochlear implant ** Contraceptive implant **Dental implant ** Fetal tissue implant ** Implantable cardioverter-defibrillator ** Orthopedic implant ** Prosthetic implant ** Retinal implant ** Subdermal implant ** Transdermal implant Alternative * Alien implants * Extraocular implant * Implant (body modification) * Implant (thought insertion) *Microchip implant (animal) (human) *'' The Implant'', a television episode of ''Seinfeld ''Seinfeld'' ( ) is an American television sitcom created by Larry David and Jerry Seinfeld that originally aired on NBC from July 5, 1989, to May 14, 1998, with a total of nine seasons consisting of List of Seinfeld episodes, 180 episodes. It ...'' See also * History of dental treatments * Implantation (other) * Osseointegration * Osseoincorporation {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mynx Vascular Closure Device
The Mynx vascular closure device is an extravascular vascular closure device (VCD) whose deployment system is designed to minimize the discomfort commonly associated with closing the small hole in the artery following catheterization procedure. The device is manufactured by AccessClosure, Inc., a medical device company located in Mountain View, California. History The Mynx received FDA Premarket Approval (PMA) in May 2007. Device description The device uses a soft, sponge-like sealant material to close the small hole in the femoral artery. The sealant works by rapidly absorbing blood and fluids around the puncture site, swelling in size and covering the hole. This seals the hole and stops the bleeding. The sealant material consists of polyethylene glycol (PEG), a water-soluble, non-thrombogenic, conformable, bio-inert polymer. PEG has an established safety profile and various forms of PEG are commonly used in a range of consumer and medical products including toothpaste, skin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyethylene Glycol
Polyethylene glycol (PEG; ) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH. PEG is commonly incorporated into hydrogels which present a functional form for further use. Uses Medical uses * Pharmaceutical-grade PEG is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms. * PEG is the basis of a number of laxatives (as ''MiraLax, RestoraLAX, MoviPrep, etc.''). Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation. Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for polyethylene glycol used as a laxative. The name may be followed by a number th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collagen
Collagen () is the main structural protein in the extracellular matrix of the connective tissues of many animals. It is the most abundant protein in mammals, making up 25% to 35% of protein content. Amino acids are bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in cartilage, bones, tendons, ligaments, and skin. Vitamin C is vital for collagen synthesis. Depending on the degree of biomineralization, mineralization, collagen tissues may be rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). Collagen is also abundant in corneas, blood vessels, the Gut (anatomy), gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and 6% by weight of skeletal muscle. The fibroblast is the most common cell creating collagen in animals. Gelatin, which is used in food and industry, is collagen t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vascular Closure Device
Vascular closure devices (VCDs) are medical devices used to achieve hemostasis of the small hole in the artery after a cardiovascular procedure of endovascular surgery requiring a catheterization. Cardiovascular procedures requiring catheterization include diagnostic procedures that help diagnose diseased blood vessels and interventional procedures such as angioplasty, the placement of a stent and coronary thrombectomy. During such procedures, a small incision is made in the groin area and a hole is created in the femoral artery to gain access to the artery. This hole is referred to as the access site or puncture site. At the completion of the procedure, the hole needs to be closed. Metal clip-based and suture-based VCDs may reduce time to hemostasis when compared with extrinsic (manual or mechanical) compression. However, no type of VCD has been shown to be more effective or safe than another. Goals The main goal of a vascular closure device is to provide rapid hemostasis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambulation
Walking (also known as ambulation) is one of the main gaits of terrestrial locomotion among legged animals. Walking is typically slower than running and other gaits. Walking is defined as an "inverted pendulum" gait in which the body vaults over the stiff limb or limbs with each step. This applies regardless of the usable number of limbs—even arthropods, with six, eight, or more limbs, walk. In humans, walking has health benefits including improved mental health and reduced risk of cardiovascular disease and death. Difference from running The word ''walk'' is descended from the Old English ''wealcan'' 'to roll'. In humans and other bipeds, walking is generally distinguished from running in that only one foot at a time leaves contact with the ground and there is a period of double-support. In contrast, running begins when both feet are off the ground with each step. This distinction has the status of a formal requirement in competitive walking events. For quadrupedal specie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Femoral Artery
The femoral artery is a large artery in the thigh and the main arterial supply to the thigh and leg. The femoral artery gives off the deep femoral artery and descends along the anteromedial part of the thigh in the femoral triangle. It enters and passes through the adductor canal, and becomes the popliteal artery as it passes through the adductor hiatus in the adductor magnus near the junction of the middle and distal thirds of the thigh. The femoral artery proximal to the origin of the deep femoral artery is referred to as the ''common femoral artery'', whereas the femoral artery distal to this origin is referred to as the ''superficial femoral artery''. Structure The femoral artery represents the continuation of the external iliac artery beyond the inguinal ligament underneath which the vessel passes to enter the thigh. The vessel passes under the inguinal ligament just medial of the midpoint of this ligament, midway between the anterior superior iliac spine and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiovascular
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek meaning ''heart'', and Latin meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Many invertebrates such as arthropods have an open circulatory system with a heart ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Groin
In human anatomy, the groin, also known as the inguinal region or iliac region, is the junctional area between the torso and the thigh. The groin is at the front of the body on either side of the pubic tubercle, where the lower part of the abdominal wall meets the thigh. A fold or crease is formed at this junction known as the inguinal groove, or crease. This is also the area of the medial compartment of thigh, medial compartment of the thigh that contains attachments of the adductor muscles of the hip or the groin muscles. The groin is the common site for a hernia. Gross anatomy Where the lower part of the anterior abdominal wall meets the thigh, a crease is formed known as the inguinal groove or crease. The junction is the area of the medial compartment of thigh, medial compartment of the thigh that contains the attachments of the adductor muscles of the hip, also known as the groin muscles. The adductor muscles that make up the groin consist of the adductor brevis, adductor l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thrombectomy
Mechanical thrombectomy, or simply thrombectomy, is the removal of a blood clot (thrombus) from a blood vessel, often and especially endovascularly as an interventional radiology procedure called endovascular thrombectomy (EVT). It thus contrasts with thrombolysis (clot dissolution) by thrombolytic medications (e.g., alteplase, reteplase), as either alternative or complement thereto. It is commonly performed in the cerebral arteries ( interventional neuroradiology) as treatment to reverse the ischemia in some ischemic strokes (i.e., those in which the blockage is a suitable candidate for such retrieval). Open vascular surgery versions of thrombectomy also exist. The effectiveness of thrombectomy for strokes was confirmed in several randomised clinical trials conducted at various medical centers throughout the United States, as reported in a seminal multistudy report in 2015. Applications in brain Ischemic stroke represents the fifth most common cause of death in the wes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
