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Tricaine Mesilate
Tricaine mesylate (Tricaine methanesulfonate, TMS, MS-222, Syncaine, Tricaine-S,), is white powder used for anesthesia, sedation, or euthanasia of fish. TMS is the only anesthetic licensed in the United States for fin fish that are intended for human consumption. The drug can have selective toxicity for poikilotherms due to their lower rate of metabolism in the liver. Tricaine is an anaesthetic that operates by preventing sodium ions to enter the cell and thus silencing action potentials. This has the net effect of blocking signal exchange between the brain and extremities. MSD Animal Health is one of the largest manufacturers of Tricaine in Norway and other European markets under the brand name Finquel. The largest manufacturer of Tricaine in North America is Syndel under the brand name Syncaine. Syncaine is manufactured in Ferndale, Washington, in the United States. Syncaine is used for handling fish, amphibians, and other cold-blooded animals during manual spawning, as well ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of procedures that would otherwise require physical restraint in a non-anesthetized individual, or would otherwise be technically unfeasible. Three broad categories of anesthesia exist: * ''General anesthesia'' suppresses central nervous system activity and results in unconsciousness and total lack of Sensation (psychology), sensation, using either injected or inhaled drugs. * ''Sedation'' suppresses the central nervous system to a lesser degree, inhibiting both anxiolysis, anxiety and creation of long-term memory, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euthanasia
Euthanasia (from : + ) is the practice of intentionally ending life to eliminate pain and suffering. Different countries have different Legality of euthanasia, euthanasia laws. The British House of Lords Select committee (United Kingdom), select committee on medical ethics defines euthanasia as "a deliberate intervention undertaken with the express intention of ending a life to relieve intractable suffering". In the Netherlands and Belgium, euthanasia is understood as "termination of life by a doctor at the request of a patient". The Dutch law, however, does not use the term 'euthanasia' but includes the concept under the broader definition of "assisted suicide and termination of life on request". Euthanasia is categorised in different ways, which include Voluntary euthanasia, voluntary, Non-voluntary euthanasia, non-voluntary, and Involuntary euthanasia, involuntary. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poikilotherm
A poikilotherm () is an animal (Greek ''poikilos'' – 'various', 'spotted', and ''therme'' – 'heat') whose internal temperature varies considerably. Poikilotherms have to survive and adapt to environmental stress. One of the most important stressors is outer environment temperature change, which can lead to alterations in membrane lipid order and can cause protein unfolding and denaturation at elevated temperatures. ''Poikilotherm'' is the opposite of ''homeotherm'' – an animal which maintains thermal homeostasis. In principle, the term could be applied to any organism, but it is generally only applied to vertebrate animals. Usually the fluctuations are a consequence of variation in the ambient environmental temperature. Many terrestrial ectotherms are poikilothermic. However some ectotherms seek constant-temperature environments to the point that they are able to maintain a constant internal temperature, and are considered actual or practical homeotherms. It is this dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Action Potentials
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of excitable cells, which include animal cells like neurons and muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell–cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward synaptic boutons situated at the ends of an axon; these signals can then connect with other neurons at synapses, or to motor cells or glands. In other types of cells, their mai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as visual perception, vision, hearing, and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing that information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective segmentation (biology), body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a brain vesicle, vesicular enlargement at the rostral (anatomical term), rostral end of the neural tube, with centralized control over all body segments. All vertebr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ferndale, Washington
Ferndale is a city in Whatcom County, Washington, United States. The population was 15,048 at the 2020 census. and according to 2023 census estimates, the city is estimated to have a population of 15,992. Ferndale is the third largest city in Whatcom County and is situated near the Lummi Nation within the Bellingham metropolitan area. History A Lummi settlement was historically located on a prairie on the east bank of the Ferndale area. Early European settlers call the area near the Nooksack River the "lower crossing" to distinguish it from the principal river crossing at Everson. Billy Clark, a Texan who came to the Northwest during the Gold Rush, was the first European full-time resident of what eventually became the City of Ferndale. He lived here with his wife and family for over a decade. First settled in 1872, Ferndale was given its name because of the ferns that once grew around the original school house. Ferndale was originally called Jam because the town was located n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amphibian
Amphibians are ectothermic, anamniote, anamniotic, tetrapod, four-limbed vertebrate animals that constitute the class (biology), class Amphibia. In its broadest sense, it is a paraphyletic group encompassing all Tetrapod, tetrapods, but excluding the amniotes (tetrapods with an amniotic membrane, such as modern reptiles, birds and mammals). All extant taxon, extant (living) amphibians belong to the monophyletic subclass (biology), subclass Lissamphibia, with three living order (biology), orders: Anura (frogs and toads), Urodela (salamanders), and Gymnophiona (caecilians). Evolved to be mostly semiaquatic, amphibians have adapted to inhabit a wide variety of habitats, with most species living in freshwater ecosystem, freshwater, wetland or terrestrial ecosystems (such as riparian woodland, fossorial and even arboreal habitats). Their biological life cycle, life cycle typically starts out as aquatic animal, aquatic larvae with gills known as tadpoles, but some species have devel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Bicarbonate
Sodium bicarbonate ( IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda (or simply “bicarb” especially in the UK) is a chemical compound with the formula NaHCO3. It is a salt composed of a sodium cation ( Na+) and a bicarbonate anion (). Sodium bicarbonate is a white solid that is crystalline but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda ( sodium carbonate). The natural mineral form is nahcolite, although it is more commonly found as a component of the mineral trona. As it has long been known and widely used, the salt has many different names such as baking soda, bread soda, cooking soda, brewing soda and bicarbonate of soda and can often be found near baking powder in stores. The term ''baking soda'' is more common in the United States, while ''bicarbonate of soda'' is more common in Australia, the United Kingdom, and New Zealand. Abbreviated colloquial forms such as '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
General Anesthetics
General anaesthetics (or anesthetics) are often defined as compounds that induce a loss of consciousness in humans or loss of righting reflex in animals. Clinical definitions are also extended to include an induced coma that causes lack of awareness to painful stimuli, sufficient to facilitate surgical applications in clinical and veterinary practice. General anaesthetics do not act as analgesics and should also not be confused with sedatives. General anaesthetics are a structurally diverse group of compounds whose mechanisms encompass multiple biological targets involved in the control of neuronal pathways. The precise workings are the subject of some debate and ongoing research. General anesthetics elicit a state of general anesthesia. It remains somewhat controversial regarding how this state should be defined. General anesthetics, however, typically elicit several key reversible effects: immobility, analgesia, amnesia, unconsciousness, and reduced autonomic responsiveness to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
