Translocated Actin-recruiting Phosphoprotein
The translocated actin-recruiting phosphoprotein (Tarp) is a protein that may mediate the invasion of epithelial cells by ''Chlamydia trachomatis'' using a type three secretion system The type III secretion system (T3SS or TTSS) is one of the bacterial secretion systems used by bacteria to secretion, secrete their Bacterial effector protein, effector proteins into the host's cells to promote virulence and Colonisation (biology .... References Phosphoproteins {{protein-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Epithelial
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of many internal organs, the corresponding inner surfaces of body cavities, and the inner surfaces of blood vessels. Epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. These tissues also lack blood or lymph supply. The tissue is supplied by nerves. There are three principal shapes of epithelial cell: squamous (scaly), columnar, and cuboidal. These can be arranged in a singular layer of cells as simple epithelium, either simple squamous, simple columnar, or simple cuboidal, or in layers of two or more cells deep as stratified (layered), or ''compound'', either squamous, columnar or cuboidal. In some tissues, a layer of columnar cells may appear to be stratified due ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chlamydia Trachomatis
''Chlamydia trachomatis'' () is a Gram-negative, Anaerobic organism, anaerobic bacterium responsible for Chlamydia infection, chlamydia and trachoma. ''C. trachomatis'' exists in two forms, an extracellular infectious elementary body (EB) and an intracellular non-infectious reticulate body (RB). The EB attaches to host cells and enter the cell using Effector (biology), effector proteins, where it transforms into the metabolically active RB. Inside the cell, RBs rapidly replicate before transitioning back to EBs, which are then released to infect new host cells. The earliest description of ''C. trachomatis'' was in 1907 by Stanislaus von Prowazek and Ludwig Halberstädter as a protozoan. It was later thought to be a virus due to its small size and inability to grow in laboratories. It was not until 1966 when it was discovered as a bacterium by Electron microscope, electron microscopy after its internal structures were visually observed. There are currently 18 Serotype, serovars of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Type Three Secretion System
The type III secretion system (T3SS or TTSS) is one of the bacterial secretion systems used by bacteria to secretion, secrete their Bacterial effector protein, effector proteins into the host's cells to promote virulence and Colonisation (biology), colonisation. While the type III secretion system has been widely regarded as equivalent to the injectisome, many argue that the injectisome is only part of the type III secretion system, which also include structures like the flagellar export apparatus. The T3SS is a needle-like protein complex found in several species of pathogenic bacteria, pathogenic gram-negative bacteria. Overview The term '''Type III secretion system was coined in 1993. This secretion system is distinguished from at least five other secretion, secretion systems found in gram-negative bacteria. Many animal and plant associated bacteria possess similar T3SSs. These T3SSs are similar as a result of convergent evolution and phylogenetic analysis supports a model i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Guangming Zhong
Guangming Zhong is a microbiologist who is currently Dielmann Endowed Chair of Genetic and Environmental Risk at University of Texas Health Science Center at San Antonio. His lab works on microbial interactions and the development of vaccines for chlamydial infection. He holds an MD in preventive medicine and MS in microbiology from Xiangya Medical School, Central South University, China, and completed his PhD in microbiology at the University of Manitoba, Canada. He has an h-index of 54 according to Semantic Scholar Semantic Scholar is a research tool for scientific literature. It is developed at the Allen Institute for AI and was publicly released in November 2015. Semantic Scholar uses modern techniques in natural language processing to support the resear .... References Year of birth missing (living people) Living people Central South University alumni University of Manitoba alumni University of Texas Health Science Center at San Antonio faculty {{Biologis ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |