Tofla Virus
   HOME





Tofla Virus
Tofla virus (''Orthonairovirus japonicum'') is a species of virus in the genus ''Orthonairovirus'' belonging to the Crimean-Congo hemorrhagic fever serogroup. It was isolated in 2016 from ''Ixodid'' in Japan. See also * Wetland virus Wetland virus or WELV is a tick borne '' Orthonairovirus'' which can infect humans. It can produce fever, headache, dizziness, malaise, arthritis and less commonly petechiae, localized lymphadenopathy. Complications may include neurological symp ... References Nairoviridae Infraspecific virus taxa {{virus-stub ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Orthonairovirus
''Orthonairovirus'' is a genus of viruses in the family '' Nairoviridae'' of the order '' Hareavirales'' which includes viruses with circular, negative-sense single stranded RNA. The name is derived from the Nairobi sheep disease which affects the gastrointestinal tracts of sheep and goats. All viruses in this genus are tick-borne viruses with human or other vertebrate hosts. Structure The virions for viruses in this genus have a spherical shape. They range in size from about 80–120 nm in diameter, with 50% of their weight attributed to proteins and 20–30% of their weight attributed to lipids. The ribonucleocapsid is filamentous, having a length of about 200-300 nm and a width of about 2–2.5 nm. These nucleocapsids are surrounded by a single envelope that has projections made of glycoproteins protruding from its surface. These projections evenly cover the surface of the virion, and are about 5–10 nm long. They aid in attachment to the host r ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Ixodid
The Ixodidae are the family of hard ticks or scale ticks, one of the three families of ticks, consisting of 771 species, . They are known as 'hard ticks' because they have a scutum or hard shield, which the other major family of ticks, the 'soft ticks' (Argasidae), lack. They are ectoparasites of a wide range of host species, and some are vectors of pathogens that can cause human disease. Description They are distinguished from the Argasidae by the presence of a scutum. In both the nymph and the adult, a prominent gnathosoma (or capitulum, mouth and feeding parts) projects forward from the animal's body; in the Argasidae, conversely, the gnathosoma is concealed beneath the body. They differ, too, in their lifecycle; Ixodidae that attach to a host bite painlessly and are generally unnoticed, and they remain in place until they engorge and are ready to change their skin; this process may take days or weeks. Some species drop off the host to moult in a safe place, whereas others ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Japan
Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea in the south. The Japanese archipelago consists of four major islands—Hokkaido, Honshu, Shikoku, and Kyushu—and List of islands of Japan, thousands of smaller islands, covering . Japan has a population of over 123 million as of 2025, making it the List of countries and dependencies by population, eleventh-most populous country. The capital of Japan and List of cities in Japan, its largest city is Tokyo; the Greater Tokyo Area is the List of largest cities, largest metropolitan area in the world, with more than 37 million inhabitants as of 2024. Japan is divided into 47 Prefectures of Japan, administrative prefectures and List of regions of Japan, eight traditional regions. About three-quarters of Geography of Japan, the countr ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Wetland Virus
Wetland virus or WELV is a tick borne '' Orthonairovirus'' which can infect humans. It can produce fever, headache, dizziness, malaise, arthritis and less commonly petechiae, localized lymphadenopathy. Complications may include neurological symptoms. Virology The Wetland virus orthonairovirus (WELV) is a member of the genus '' Orthonairovirus'', family '' Nairoviridae'' of RNA viruses. It was first identified in 2019 in a Chinese person in Jinzhou, Liaoning province Northeast China after a visit to a wetland park in Yakeshi, Inner Mongolia. Three different strains were identified one from the patient and two from ticks. Its sequence is most similar to the Tofla virus from Japan. Hosts and transmission The Wetland virus was found in mice, sheep, pigs, and horses, but not dogs or cattle. It was found in about 2% of 14,500 different ticks in Northeast China with the highest prevalence (6%) in '' Haemaphysalis concinna''. Experimental infection showed that WELV caused lethal ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Nairoviridae
''Nairoviridae'' is a family of viruses in the order '' Hareavirales''. Its name derives from Nairobi sheep disease, caused by the member ''Nairobi sheep disease orthonairovirus Nairobi sheep disease virus (NSDV), also known as Ganjam virus, is a species in the genus '' Orthonairovirus'' belonging to the Nairobi sheep disease serogroup. NSDV is enzootic, becoming epizootic when denser populations of susceptible animals ...''. Taxonomy The family contains the following genera: * '' Norwavirus'' * '' Ocetevirus'' * '' Orthonairovirus'' * '' Sabavirus'' * '' Shaspivirus'' * '' Sitinavirus'' * '' Striwavirus'' * '' Xinspivirus'' References External links ICTV Report: ''Nairoviridae'' {{Taxonbar, from=Q29001081 Virus families ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]