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Supernumerary Kidney
A supernumerary kidney is an additional kidney to the number usually present in an organism. This often develops as the result of splitting of the nephrogenic blastema, or from separate metanephric blastema The metanephrogenic blastema or metanephric blastema (or metanephric mesenchyme, or metanephric mesoderm) is one of the two embryological structures that give rise to the kidney, the other being the ureteric bud. The metanephric blastema mostly de ...s into which partially or completely reduplicated ureteral stalks enter to form separate capsulated kidneys; in some cases the separation of the reduplicated organ is incomplete (fused supernumerary kidney). Less than a hundred cases are known of one or two supernumerary kidneys. See also * Supernumerary body part References * Supernumerary body parts Nephrology {{genitourinary-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Supernumerary Body Part
Supernumerary body parts are most commonly a congenital disorder involving the growth of an additional part of the body and a deviation from the body plan. Body parts may be easily visible or hidden away, such as internal organs. Many additional body parts form by the same process as conjoined twins: the zygote begins to split but fails to completely separate. This condition may also be a symptom of repeated occurrences of continuous inbreeding in a genetic line. Specific types of occurrence Specific types of additional body parts include: *Accessory breast – one or more additional breastsOnline Mendelian Inheritance in Man. Nipples, Supernumerary. Accessed 10 July 2006. * Accessory spleen – one or more additional spleens *Cervical rib – an additional rib * Diphallia – having two penes/penises * Hermaphroditism – having both male and female sex organs * Hyperdontia – additional teeth * Pelvic digit – a bony growth in the soft tissue of the pelvic region *Polycep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Supernumerary Body Parts
Supernumerary body parts are most commonly a congenital disorder involving the growth of an additional part of the body and a deviation from the body plan. Body parts may be easily visible or hidden away, such as internal organs. Many additional body parts form by the same process as conjoined twins: the zygote begins to split but fails to completely separate. This condition may also be a symptom of repeated occurrences of continuous inbreeding in a genetic line. Specific types of occurrence Specific types of additional body parts include: *Accessory breast – one or more additional breastsOnline Mendelian Inheritance in Man. Nipples, Supernumerary. Accessed 10 July 2006. *Accessory spleen – one or more additional spleens *Cervical rib – an additional rib * Diphallia – having two penes/penises *Hermaphroditism – having both male and female sex organs *Hyperdontia – additional teeth * Pelvic digit – a bony growth in the soft tissue of the pelvic region *Polycephaly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blastema
A blastema (Greek ''βλάστημα'', "offspring") is a mass of cells capable of growth and regeneration into organs or body parts. The changing definition of the word "blastema" has been reviewed by Holland (2021). A broad survey of how blastema has been used over time brings to light a somewhat involved history. The word entered the biomedical vocabulary in 1799 to designate a sinister acellular slime that was the starting point for the growth of cancers, themselves, at the time, thought to be acellular, as reviewed by Hajdu (2011, Cancer 118: 1155-1168). Then, during the early nineteenth century, the definition broadened to include growth zones (still considered acellular) in healthy, normally developing plant and animal embryos. Contemporaneously, cancer specialists dropped the term from their vocabulary, perhaps because they felt a term connoting a state of health and normalcy was not appropriate for describing a pathological condition. During the middle decades of the nin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metanephric Blastema
The metanephrogenic blastema or metanephric blastema (or metanephric mesenchyme, or metanephric mesoderm) is one of the two embryological structures that give rise to the kidney, the other being the ureteric bud. The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system. The system of tissue induction between the ureteric bud and the metanephric blastema is a reciprocal control system. GDNF, GDNF, glial cell-derived neurotrophic factor, is produced by the metanephric blastema and is essential in binding to the RET proto-oncogene, Ret receptor on the ureteric bud, which bifurcates and coalesces as a result to form the renal pelvis, major and minor Renal calyx, calyces and collecting ducts. Mutations in the ''EYA1'' gene, whose product regulates ''GDNF'' expression in the developing kidney, lead to the renal abnormalities of BOR syndrome (branchio-oto-renal syndrome). See also * Mesenchyme * Metanephros * Blastema * Kidney developm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
