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Streptomyces Tsukubensis
''Streptomyces tsukubensis'' is a bacterium species from the genus of ''Streptomyces'' which has been isolated from soil in Ibaraki in Japan.Deutsche Sammlung von Mikroorganismen und Zellkulturenbr>/ref> ''Streptomyces tsukubensis'' produces the immunosuppressant tacrolimus Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After Allotransplantation, allogenic organ transplant, the risk of organ Transplant rejection, rejection is moderate. To lower the risk of organ rejectio .... See also * List of ''Streptomyces'' species References Further reading * * * * External linksType strain of ''Streptomyces tsukubensis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase tsukubensis Bacteria described in 2013 {{Streptomyces-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces
''Streptomyces'', from στρεπτός (''streptós''), meaning "twisted", and μύκης (''múkés''), meaning "fungus", is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. Over 700 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have very large genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Different strains of the same species may colonize very diverse environments. Streptomycetes are characterised by a complex secondary metabolism. Between 5-23% (average: 12%) of the protein-coding genes of each ''Streptomyces'' species are implicated in secondary metabolism. Streptomycetes produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ibaraki Prefecture
is a Prefectures of Japan, prefecture of Japan located in the Kantō region of Honshu. Ibaraki Prefecture has a population of 2,828,086 (1 July 2023) and has a geographic area of . Ibaraki Prefecture borders Fukushima Prefecture to the north, Tochigi Prefecture to the northwest, Saitama Prefecture to the southwest, Chiba Prefecture to the south, and the Pacific Ocean to the east. Mito, Ibaraki, Mito, the capital, is the largest city in Ibaraki Prefecture. Other major cities include Tsukuba, Ibaraki, Tsukuba, Hitachi, Ibaraki, Hitachi, and Hitachinaka, Ibaraki, Hitachinaka. Ibaraki Prefecture is located on Japan's eastern Pacific coast to the northeast of Tokyo, and is part of the Greater Tokyo Area, the most populous metropolitan area in the world. Ibaraki Prefecture features Lake Kasumigaura, the second-largest lake in Japan; the Tone River, Japan's second-longest river and largest drainage basin; and Mount Tsukuba, one of the most famous mountains in Japan. Ibaraki Prefectur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Japan
Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea in the south. The Japanese archipelago consists of four major islands—Hokkaido, Honshu, Shikoku, and Kyushu—and List of islands of Japan, thousands of smaller islands, covering . Japan has a population of over 123 million as of 2025, making it the List of countries and dependencies by population, eleventh-most populous country. The capital of Japan and List of cities in Japan, its largest city is Tokyo; the Greater Tokyo Area is the List of largest cities, largest metropolitan area in the world, with more than 37 million inhabitants as of 2024. Japan is divided into 47 Prefectures of Japan, administrative prefectures and List of regions of Japan, eight traditional regions. About three-quarters of Geography of Japan, the countr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deutsche Sammlung Von Mikroorganismen Und Zellkulturen
The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: ''Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH''), located in Braunschweig, is a research infrastructure in the Leibniz Association. Originally a culture collection for microbes (DSM), the DSMZ has expanded to provide cell cultures, online bioinformatic services, and offline analysis services. It also hosts research projects. As of 2021, DSMZ is the world's most diverse collection of bioresources with 75,000 different accessions. These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1,500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD from the University of Konstanz. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunosuppressant
Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system. Classification Immunosuppressive drugs can be classified into five groups: * glucocorticoids * cytostatics * antibodies * drugs acting on immunophilins * other drugs Glucocorticoids In pharmacologic (supraphysiologic) doses, glucocorticoids, such as prednisone, dexamethasone, and hydrocortisone are used to suppress various allergic, inflammatory, and autoimmune disorders. They are also administered as posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Nevertheless, they do not prevent an infection and also inhibit later reparative processes. Immunosuppressive mechanism Glucocorticoids suppress cell-mediated immunity. They act by inhibiting gene expression of cytokines including Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tacrolimus
Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After Allotransplantation, allogenic organ transplant, the risk of organ Transplant rejection, rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T cell-mediated diseases such as atopic dermatitis, eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat Dry eye syndrome#Other, dry eye syndrome in cats and dogs. Tacrolimus inhibits calcineurin, which is involved in the production of interleukin-2, a molecule that promotes the development and cell proliferation, proliferation of T cells, as part of the body's learned (or adaptive immune response, adaptive) immune response. Chemically, it is a macrolide lactone that was first discovered in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Streptomyces Species
The following is a list of ''Streptomyces'' species, organized alphabetically by species name. Names that have not been validated according to the Bacteriological Code are enclosed in "quotes". , there are 679 valid species of ''Streptomyces'' and an additional 121 provisional species. New species continue to be discovered (''e.g.'', '' S. gossypiisoli'', described in 2021). Many species are named after their colorful hyphae and/or spores. A * '' Streptomyces abietis'' Fujii ''et al''. 2013 * '' Streptomyces abikoensis'' (Umezawa ''et al''. 1951) Witt and Stackebrandt 1991 * '' Streptomyces abyssalis'' Xu ''et al''. 2012 * "'' Streptomyces abyssomicinicus''" Komaki ''et al''. 2020 * '' Streptomyces achromogenes'' Okami and Umezawa 1953 (Approved Lists 1980) * '' Streptomyces acidicola'' Lipun ''et al''. 2020 * ''Streptomyces acidiscabies'' Lambert and Loria 1989 * '' Streptomyces actinomycinicus'' Tanasupawat ''et al''. 2016 * "'' Streptomyces actuosus''" Pinnert ''et al''. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
