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Streptomyces Chrysomallus
''Streptomyces anulatus'' is a bacterium species from the genus ''Streptomyces'' which has been isolated from soil. ''Streptomyces anulatus'' produces cactinomycin, endophenazine A, endophenazine B, tubermycin B, endophenazine C, epocarbazolin A, epocarbazolin B, dextranase, telomestatin and actinomycin C. See also * List of Streptomyces species, List of ''Streptomyces'' species References Further reading * * * * * * * * * * * External linksType strain of ''Streptomyces anulatus'' at Bac''Dive'' – the Bacterial Diversity Metadatabase Streptomyces, anulatus Bacteria described in 1953 {{Streptomyces-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deutsche Sammlung Von Mikroorganismen Und Zellkulturen
The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: ''Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH''), located in Braunschweig, is a research infrastructure in the Leibniz Association. Also the DSMZ is the world's most diverse collection of bioresources (status 2021: 75,000 bioresources). These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1. 500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD. He holds a professorship in microbiology at the Technical University of Braunschweig. Since August 2018, he has led the institute in a dual leadership with Bettina Fischer as administrative director. History Structu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces
''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Streptomycetes are characterised by a complex secondary metabolism. They produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomycin, streptomycin, cypemycin, grisemycin, bottromycins and chloramphenicol). The antibiotic streptomycin takes its name directly from ''Streptomyces''. Streptomycetes are infrequent pathogens, though infections in humans, such as mycetoma, can be caused by '' S. somaliensis'' and '' S. sudanensis'', and in plants can be caused by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endophenazine A
Endophenazine A is a phenazine derivative with the molecular formula C18H16N2O2 which is produced by the bacterium ''Streptomyces anulatus ''Streptomyces anulatus'' is a bacterium species from the genus ''Streptomyces'' which has been isolated from soil. ''Streptomyces anulatus'' produces cactinomycin, endophenazine A, endophenazine B, tubermycin B, endophenazine C, epocarbazo ...''. References Further reading * * Endophenazine A Carboxylic acids {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dextranase
Dextranase (, dextran hydrolase, endodextranase, dextranase DL 2, DL 2, endo-dextranase, α-D-1,6-glucan-6-glucanohydrolase, 1,6-α-D-glucan 6-glucanohydrolase) is an enzyme with systematic name 6-α-D-glucan 6-glucanohydrolase. It catalyses the following chemical reaction A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and break ... : Endohydrolysis of (1→6)-α-D-glucosidic linkages in dextran References External links * EC 3.2.1 {{Enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Telomestatin
Telomestatin is a macrocyclic chemical compound that acts by inhibiting the telomerase activity of ''in vitro'' cancer cells. It was first isolated from the bacteria '' Streptomyces anulatus''. Telomestatin induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region. Upon formation of G4 structure there will be a decrease in the activity of the telomerase, which is involved in the replication of the telomeres and as a result the cell dies due to Hayflick type senescence Senescence () or biological aging is the gradual deterioration of functional characteristics in living organisms. The word ''senescence'' can refer to either cellular senescence or to senescence of the whole organism. Organismal senescence inv .... References {{reflist Macrocycles Oxazoles Thiazolines Telomeres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actinomycin C
Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. It is given by injection into a vein. Most people develop side effects. Common side effects include bone marrow suppression, vomiting, mouth ulcers, hair loss, liver problems, infections, and muscle pains. Other serious side effects include future cancers, allergic reactions, and tissue death at the site of injection. Use in pregnancy may harm the baby. Dactinomycin is in the cytotoxic antibiotic family of medications. It is believed to work by blocking the creation of RNA. Dactinomycin was approved for medical use in the United States in 1964. It is on the World Health Organization's List of Essential Medicines. Medical use Actinomycin is a clear, yellowish liquid administered intravenously and most commonly used in treat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
