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Strategies For Engineered Negligible Senescence
Strategies for engineered negligible senescence (SENS) is a range of proposed regenerative medical therapies, either planned or currently in development, for the periodic repair of all age-related damage to human tissue. These therapies have the ultimate aim of maintaining a state of negligible senescence in patients and postponing age-associated disease.de Grey, Aubrey; Rae, Michael (September 2007). ''Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in Our Lifetime''. New York, NY: St. Martin's Press, 416 pp. . SENS was first defined by British biogerontologist Aubrey de Grey. Many mainstream scientists believe that it is a fringe theory. De Grey later highlighted similarities and differences of SENS to subsequent categorization systems of the biology of aging, such as the highly influential ''Hallmarks of Aging'' published in 2013. While some biogerontologists support the SENS program, others contend that the ultimate goals of de Grey's programme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regenerative Medicine
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs. Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and implanting them when the body cannot heal itself. When the cell source for a regenerated organ is derived from the patient's own tissue or cells, the challenge of organ transplant rejection via immunological mismatch is circumvented. This approach could alleviate the problem of the shortage of organs available for donation. Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells. Examples include the injection of stem cells or progenitor cells obtained through directed differe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aging-associated Diseases
An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age ( with rare exceptions) but not all adult animals experience all age-associated diseases. The term does not refer to age-specific diseases, such as the childhood diseases chicken pox and measles, only diseases of the elderly. They are also not accelerated aging diseases, all of which are genetic disorders. Examples of aging-associated diseases are atherosclerosis and cardiovascular disease, cancer, arthritis, cataracts, osteoporosis, type 2 diabetes, hypertension and Alzheimer's disease. The incidence of all of these diseases increases exponentially with age. Of the roughly 150,000 people who die each day across the globe, about two thirds—100,000 per day—die of age-related causes. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vikram Sheel Kumar
Vikram Sheel Kumar (born 1976) is an American engineer, doctor, and entrepreneur. Early life and education Vikram Kumar was born in the United States to an Indian-American family. His father was a neurosurgeon. As a child, the family returned to India, where Kumar attended the Modern School in New Delhi. After graduation, he studied engineering at the Indian Institute of Technology. In 1996, Kumar returned to the United States and received a BS in operations research from Columbia University in 1999. He then studied medicine and business at the Harvard-MIT Division of Health Sciences and Technology, which was supported by The Paul & Daisy Soros Fellowships for New Americans. Career In 2002, Kumar co-founded Dimagi, a for-profit software company which develops open-source software technology for doctors in impoverished areas. Kumar currently serves as the company's Chief Medical Officer (CMO). He also co-founded Cogito Corp, a startup which uses a mobile-phone-based voice ana ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nathan Myhrvold
Nathan Paul Myhrvold (born August 3, 1959), formerly Chief Technology Officer at Microsoft, is co-founder of Intellectual Ventures and the principal author of ''Modernist Cuisine'' and its successor books. Early life and education Myhrvold was born on August 3, 1959, in Seattle, Washington, to Norwegian American parents. He was raised in Santa Monica, California, where he attended Mirman School and Santa Monica High School, graduating in 1974, and began college at age 14. Transferring from Santa Monica College, he studied mathematics (B.Sc.), and geophysics and space physics (Master's) at UCLA. He was awarded a Hertz Foundation Fellowship for graduate study and studied at Princeton University, where he earned a master's degree in mathematical economics and completed a Ph.D. in applied mathematics after completing a doctoral dissertation titled "Vistas in curved space-time quantum field theory" under the supervision of Malcolm Perry (physicist), Malcolm Perry. For one year, h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anita Goel
Anita Goel is an American physicist, physician, and scientist in the emerging field of Nanobiophysics. At the Nanobiosym Research Institute (NBS), Goel examines the physics of life and the way nanomotors read and write information into DNA. Education Goel received a PhD and M.A. in physics from Harvard University, where she was worked with Nobel laureate Dudley R. Herschbach. Her thesis was entitled ''Single Molecule Dynamics of Motor Enzymes Along DNA''. She received a BS in physics with honors and distinction from Stanford University, where her honors thesis mentor was Nobel laureate Steven Chu. She also earned in parallel an M.D. from the Harvard–MIT The Massachusetts Institute of Technology (MIT) is a private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of modern technology and sc ... Joint Division of Health Sciences and Technology (HST). Career Goel has o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rodney Brooks
Rodney Allen Brooks (born 30 December 1954) is an Australian robotics, roboticist, Fellow of the Australian Academy of Science, author, and robotics entrepreneur, most known for popularizing the behavior based robotics, actionist approach to robotics. He was a Panasonic Professor of Robotics at the Massachusetts Institute of Technology and former director of the MIT Computer Science and Artificial Intelligence Laboratory. He is a founder and former Chief Technical Officer of iRobot and co-founder, Chairman and Chief Technical Officer of Rethink Robotics (formerly Heartland Robotics) and is the co-founder and Chief Technical Officer of Robust.AI (founded in 2019). Life Brooks received an M.A. in pure mathematics from Flinders University of South Australia. In 1981, he received a PhD in Computer Science from Stanford University under the supervision of Thomas Binford. He has held research positions at Carnegie Mellon University and Massachusetts Institute of Technology, MIT and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methuselah Foundation
The Methuselah Foundation is an American-based global non-profit organization based in Springfield, Virginia, with a declared mission to "make 90 the new 50 by 2030" by supporting tissue engineering and regenerative medicine therapies. The organization was originally incorporated by David Gobel in 2001 as the Performance Prize Society, a name inspired by the British government’s Longitude Act, which offered monetary rewards for anyone who could devise a portable, practical solution for determining a ship's longitude. Founding In 2003, David Gobel, Aubrey de Grey, and Dane Gobel rebranded the organization Methuselah Foundation, named after Methuselah, the grandfather of Noah in the Hebrew Bible, whose lifespan was recorded as 969 years. The new name was introduced at the 32nd Annual Meeting of the American Aging Association, where they awarded the first Methuselah Mouse Prize to Andrej Bartke for his work on mice that lived the equivalent of 180 human years. The Foundati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Gobel
David Gobel (born 1952 in Baltimore, Maryland) is an American philanthropist, entrepreneur, inventor, and futurist. He is and CEO of the Methuselah Foundation, CEO of the Methuselah Fund, and one of the first to publicly advance the idea of longevity escape velocity, even before this term was formulated. Career Methuselah Foundation David Gobel heads the Methuselah Foundation, a medical charity that was organized in 2000 and is based in Springfield, VA. Under Gobel's leadership, Methuselah has invested millions of dollars to support research and development in regenerative medicine, and is actively involved in efforts to change how the public thinks about extending the healthy human lifespan. With co-founders Dane Gobel and Aubrey de Grey, Gobel established Methuselah in order to, as stated on its original website, "shed light on the processes of aging and find ways to extend healthy life." The organization works in a variety of ways: Incubating companies that are developin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cambridge
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, world's third-oldest university in continuous operation. The university's founding followed the arrival of scholars who left the University of Oxford for Cambridge after a dispute with local townspeople. The two ancient university, ancient English universities, although sometimes described as rivals, share many common features and are often jointly referred to as Oxbridge. In 1231, 22 years after its founding, the university was recognised with a royal charter, granted by Henry III of England, King Henry III. The University of Cambridge includes colleges of the University of Cambridge, 31 semi-autonomous constituent colleges and List of institutions of the University of Cambridge#Schools, Faculties, and Departments, over 150 academic departm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United States, and one of the nine colonial colleges chartered before the American Revolution. Yale was established as the Collegiate School in 1701 by Congregationalism in the United States, Congregationalist clergy of the Connecticut Colony. Originally restricted to instructing ministers in theology and sacred languages, the school's curriculum expanded, incorporating humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew rapidly after 1890 due to the expansion of the physical campus and its scientif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sherwin Nuland
Sherwin may refer to: Surname: * A. N. Sherwin-White (1911–1993), British historian of Ancient Rome * Adam Sherwin, journalist and a former media correspondent for The Times between 1999 and 2010 * Amy Sherwin (1855–1935), the 'Tasmanian Nightingale', an Australian soprano singer * Arthur Sherwin (1879–1947), English cricketer who played first-class cricket for Derbyshire * Belle Sherwin (1869–1955), American Women's rights activist * Brent Sherwin (born 1978), Australian professional rugby league player * Brian Sherwin (born 1980), American art critic, writer, and blogger with a degree from Illinois College * Byron Sherwin, Jewish scholar and author with expertise in theology, inter-religious dialogue, mysticism and Jewish ethics * Charles Sherwin (1877–1950), English cricketer who played first-class cricket for Derbyshire *David Sherwin (born 1942), British screenwriter *Derrick Sherwin (1936–2018), British television producer, writer, and actor * Emily Sherwin, America ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Technology Review
''MIT Technology Review'' is a bimonthly magazine wholly owned by the Massachusetts Institute of Technology. It was founded in 1899 as ''The Technology Review'', and was re-launched without "''The''" in its name on April 23, 1998, under then publisher R. Bruce Journey. In September 2005, it was changed, under its then editor-in-chief and publisher, Jason Pontin, to a form resembling the historical magazine. Before the 1998 re-launch, the editor stated that "nothing will be left of the old magazine except the name." It was therefore necessary to distinguish between the modern and the historical ''Technology Review''. The historical magazine had been published by the MIT Alumni Association, was more closely aligned with the interests of MIT alumni, and had a more intellectual tone and much smaller public circulation. The magazine, billed from 1998 to 2005 as "MIT's Magazine of Innovation", and from 2005 onwards as simply "published by MIT", focused on new technology and how it is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
