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Sarcocystis Nesbitti
''Sarcocystis nesbitti'' is a species of Apicomplexa. __TOC__ Human infection An outbreak investigation was conducted on 93 symptomatic persons from Malaysia following a college retreat on January 17–19, 2012, on Pangkor Island. Predominant manifestations were fever (relapsing in about 50% of patients), myalgia, headache, and cough. Although only two patients were confirmed to be acutely infected with ''S. nesbitti'', the remaining students and teachers in the group likely had the same infection, because nearly all had similar signs and symptoms with onset of illness within days of each other. In addition, 9 patients had a distinctive facial myositis, but sarcocysts could not be verified in all of them because only three patients agreed to provide a muscle biopsy specimen. History of discovery In 1843, Swiss scientist Friedrich Miescher Johannes Friedrich Miescher (13 August 1844 – 26 August 1895) was a Swiss physician and biologist. He was the first scientist to isolate ...
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Apicomplexa
The Apicomplexa (also called Apicomplexia) are a large phylum of parasitic alveolates. Most of them possess a unique form of organelle that comprises a type of non-photosynthetic plastid called an apicoplast, and an apical complex structure. The organelle is an adaptation that the apicomplexan applies in penetration of a host cell. The Apicomplexa are unicellular and spore-forming. All species are obligate endoparasites of animals, except '' Nephromyces'', a symbiont in marine animals, originally classified as a chytrid fungus. Motile structures such as flagella or pseudopods are present only in certain gamete stages. The Apicomplexa are a diverse group that includes organisms such as the coccidia, gregarines, piroplasms, haemogregarines, and plasmodia. Diseases caused by Apicomplexa include: * Babesiosis ('' Babesia'') * Malaria (''Plasmodium'') * Cryptosporidiosis ('' Cryptosporidium parvum'') * Cyclosporiasis ('' Cyclospora cayetanensis'') * Cystoisosporiasis ('' Cys ...
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Malaysia
Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two regions: Peninsular Malaysia and Borneo's East Malaysia. Peninsular Malaysia shares a land and maritime Malaysia–Thailand border, border with Thailand and Maritime boundary, maritime borders with Singapore, Vietnam, and Indonesia. East Malaysia shares land and maritime borders with Brunei and Indonesia, and a maritime border with the Philippines and Vietnam. Kuala Lumpur is the national capital, the country's largest city, and the seat of the Parliament of Malaysia, legislative branch of the Government of Malaysia, federal government. The nearby Planned community#Planned capitals, planned capital of Putrajaya is the administrative capital, which represents the seat of both the Government of Malaysia#Executive, executive branch (the Cabine ...
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Pangkor Island
Pangkor Island ( ms, Pulau Pangkor) is an island in Manjung District, Perak, Malaysia. It has a population of approximately 25,000. Nearby islands include Pangkor Laut Island, Giam Island, Mentagor Island, Simpan Island, and Tukun Terindak Island. The major industries of the island are tourism and fishing. Geography Pangkor Island has a land area of and is from Peninsular Malaysia. The interior of the island is forested and is home to 65 reptile species, 17 amphibian species, and 82 total herpetofaunal species. History Historically, Pangkor was a refuge for local fishers, merchants and pirates. In the 17th century, the Dutch built a fort to control the Perak tin trade, known as the Dutch Fort. In 1874, it was the location of a historical treaty between the British government and a contender for the Perak throne (the Pangkor Treaty), which began the British colonial domination of the Malay Peninsula. The old British name for the Pangkor Island group was the Dindings. ...
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Myalgia
Myalgia (also called muscle pain and muscle ache in layman's terms) is the medical term for muscle pain. Myalgia is a symptom of many diseases. The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, especially when there has been no trauma. Long-lasting myalgia can be caused by metabolic myopathy, some nutritional deficiencies, and chronic fatigue syndrome. Causes The most common causes of myalgia are overuse, injury, and strain. Myalgia might also be caused by allergies, diseases, medications, or as a response to a vaccination. Dehydration at times results in muscle pain as well, especially for people involved in extensive physical activities such as workout. Muscle pain is also a common symptom in a variety of diseases, including infectious diseases, such as influenza, muscle abscesses, Lyme disease, malaria, trichinosis or poliomyelitis; autoimmune diseases, such as celiac disease, systemi ...
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Headache
Headache is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of depression in those with severe headaches. Headaches can occur as a result of many conditions. There are a number of different classification systems for headaches. The most well-recognized is that of the International Headache Society, which classifies it into more than 150 types of primary and secondary headaches. Causes of headaches may include dehydration; fatigue; sleep deprivation; stress; the effects of medications (overuse) and recreational drugs, including withdrawal; viral infections; loud noises; head injury; rapid ingestion of a very cold food or beverage; and dental or sinus issues (such as sinusitis). Treatment of a headache depends on the underlying cause, but commonly involves pain medication (especially in case of migraine or cluster headache). A headache is one of the most commonly experi ...
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Cough
A cough is a sudden expulsion of air through the large breathing passages that can help clear them of fluids, irritants, foreign particles and microbes. As a protective reflex, coughing can be repetitive with the cough reflex following three phases: an inhalation, a forced exhalation against a closed glottis, and a violent release of air from the lungs following opening of the glottis, usually accompanied by a distinctive sound. Frequent coughing usually indicates the presence of a disease. Many viruses and bacteria benefit, from an evolutionary perspective, by causing the host to cough, which helps to spread the disease to new hosts. Most of the time, irregular coughing is caused by a respiratory tract infection but can also be triggered by choking, smoking, air pollution, asthma, gastroesophageal reflux disease, post-nasal drip, chronic bronchitis, lung tumors, heart failure and medications such as angiotensin-converting-enzyme inhibitors (ACE inhibitors). Treatme ...
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Myositis
Myositis is a rare disease that involves inflammation of the muscles. This can present with a variety of symptoms such as skin involvement (i.e., rashes), muscle weakness, and other organ involvement. Systemic symptoms such as weight loss, fatigue, and low fever can also present. Causes Injury, medicines, infection, or an autoimmune disorder can lead to myositis. It can also be idiopathic. * Injury - A mild form of myositis can occur with hard exercise. A more severe form of muscle injury, called rhabdomyolysis, is also associated with myositis. This is a condition where injury to your muscles causes them to quickly break down. * Medicines - A variety of different medicines can cause myositis. One of the most common drug types that can cause myositis is statins. Statins are drugs that are used to help lower high cholesterol. One of the most common side effects of statin therapy is muscle pain. Rarely, statin therapy can lead to myositis. * Infection - The most common infectious c ...
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Friedrich Miescher
Johannes Friedrich Miescher (13 August 1844 – 26 August 1895) was a Swiss physician and biologist. He was the first scientist to isolate nucleic acid in 1869. He also identified protamine and made a number of other discoveries. Miescher had isolated various phosphate-rich chemicals, which he called ''nuclein'' (now nucleic acids), from the nuclei of white blood cells in Felix Hoppe-Seyler's laboratory at the University of Tübingen, Germany, paving the way for the identification of DNA as the carrier of inheritance. The significance of the discovery, first published in 1871, was not at first apparent, and Albrecht Kossel made the initial inquiries into its chemical structure. Later, Miescher raised the idea that the nucleic acids could be involved in heredity and even posited that there might be something akin to an alphabet that might explain how variation is produced. Early life and education Friedrich Miescher came from a scientific family; his father and his uncle hel ...
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Conoidasida
Conoidasida is a class of parasitic alveolates in the phylum Apicomplexa. The class was defined in 1988 by Levine and contains two subclasses – the coccidia and the gregarines. All members of this class have a complete, hollow, truncated conoid. Gregarines tend to parasitize invertebrates with the mature gamonts being extracellular, the coccidia mostly infect vertebrates and have intracellular gamonts. Description A conoid is found in most species and when present forms complete but truncated cone. Sexual and asexual reproduction are present in life cycle of all species. Each zygote normally forms an oocyst wall within which it undergoes meiosis. This is sometimes followed by mitosis. This process of sporogony produces mobile vermiform infectious sporozoites. Multiple mitotic divisions (schizogony) also occur during merogony of the feeding stages (trophozoites) and during gametogony. Motility Microgametes of some species are flagellated. Locomotion of other gametes an ...
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