STEAP3
Metalloreductase STEAP3 is an enzyme that in humans is encoded by the ''STEAP3'' gene. STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe3+) to a soluble ferrous (Fe2+) form. STEAP3 and other STEAP protein, with the exception of STEAP1, are predicted to contain a Rossmann fold, Di-nucleotide binding domain (Rossmann Fold). This has been shown using X-ray crystallography in the cases of STEAP3 and STEAP4 (PDB2VNS2VQ3
an
2YJZ
.

Interactions

STEAP3 has been shown to Protein-protein interaction, interact with BNIP3L and PKMYT1.

References

BNIP3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is a protein that in humans is encoded by the ''BNIP3L'' gene. Function This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. The protein encoded by this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression. Interactions BNIP3L has been shown to Protein-protein interaction, interact with STEAP3. References External links * Further reading

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