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SARS-CoV-2 Delta Variant
The Delta variant (B.1.617.2) was a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India on 5 October 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021. The World Health Organization (WHO) indicated in June 2021 that the Delta variant was becoming the dominant strain globally. It has mutations in the gene encoding the SARS-CoV-2 spike protein causing the substitutions T478K, P681R and L452R, which are known to affect transmissibility of the virus as well as whether it can be neutralised by antibodies for previously circulating variants of the COVID-19 virus. In August 2021, Public Health England (PHE) reported secondary attack rate in household contacts of non-travel or unknown cases for Delta to be 10.8% ''vis-à-vis'' 10.2% for the Alpha variant; the case fatality rate for those 386,835 people with Delta is 0.3%, where 46% of the cases and 6% of the deaths are unvaccinated and bel ...
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Deltacoronavirus
''Deltacoronavirus'' (Delta-CoV) is one of the four genera ('' Alpha-'', '' Beta-'', '' Gamma-'', and ''Delta-'') of coronaviruses. It is in the subfamily ''Orthocoronavirinae'' of the family ''Coronaviridae''. They are enveloped, positive-sense, single-stranded RNA viruses. Deltacoronaviruses infect mostly birds and some mammals. While the alpha and beta genera are derived from the bat viral gene pool, the gamma and delta genera are derived from the avian and pig viral gene pools. Recombination appears to be common among deltacoronaviruses.Lau SKP, Wong EYM, Tsang CC, Ahmed SS, Au-Yeung RKH, Yuen KY, Wernery U, Woo PCY. Discovery and Sequence Analysis of Four Deltacoronaviruses from Birds in the Middle East Reveal Interspecies Jumping with Recombination as a Potential Mechanism for Avian-to-Avian and Avian-to-Mammalian Transmission. J Virol. 2018 Jul 17;92(15):e00265-18. doi: 10.1128/JVI.00265-18. Print 2018 Aug 1. PMID 29769348 Recombination occurs frequently in the vira ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 ( COVID19). Knowledge about the structure and function of previous coronaviruses causing diseases like severe acute respiratory syndrome ( SARS) and Middle East respiratory syndrome ( MERS) accelerated the development of various vaccine platforms in early 2020. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. However, immunity from the vaccines wanes over time, requiring people to get booster doses of the vaccine to maintain protection against COVID19. The COVID19 vaccines are widely credited for their role in reducing the spread of COVID19 and reducing the severity and death caused by COVID19. Many countries implemented phased distribution plans that prioritized those at highest risk of comp ...
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COVID-19 Pandemic In New Zealand
The COVID-19 pandemic in New Zealand was part of COVID-19 pandemic, the pandemic of COVID-19, coronavirus disease 2019 () caused by SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 (). The first case of the disease in New Zealand was reported on 28 February 2020. The country recorded over 2,274,370 cases (2,217,047 confirmed and 57,323 probable). Over 3,000 people died as a result of the pandemic, with cases recorded in all twenty district health board (DHB) areas. The pandemic first peaked in early April 2020, with 89 new cases recorded per day and 929 active cases. Cases peaked again in October 2021 with 134 new cases reported on 22 October. In response to the first outbreak in late February 2020, the New Zealand Government closed the country's borders and imposed COVID-19 lockdowns, lockdown restrictions. A four-tier #Alert level system, alert level system was introduced on 21 March 2020 to manage the outbreak within New Zealand. After a two-month nationwide ...
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COVID-19 Pandemic In Australia
The COVID-19 pandemic in Australia was a part of the COVID-19 pandemic, worldwide pandemic of the coronavirus disease 2019 () caused by SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first confirmed case in Australia was identified on 25 January 2020, in Victoria (Australia), Victoria, when a man who had returned from Wuhan, Hubei Province, China, tested positive for the virus. , Australia has reported over 11,350,000 cases and 19,265 deaths, with Victoria's 2020 second wave having the highest fatality rate per case. In March 2020, the Australian government established the intergovernmental National Cabinet (Australia), National Cabinet and declared a Biosecurity Act 2015, human biosecurity emergency in response to the outbreak. Australian borders were closed to all non-residents on 20 March, and returning residents were required to spend two weeks in supervised quarantine hotels from 27 March. Many individual states and territories also closed t ...
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COVID-19 Pandemic In The United States
On December 31, 2019, China announced the discovery of a cluster of pneumonia cases in Wuhan. The first American case was reported on January 20, and United States Department of Health and Human Services, Health and Human Services Secretary Alex Azar declared a Public health emergency (United States), public health emergency on January 31. Restrictions were placed on flights arriving from China, but the initial U.S. response to the pandemic was otherwise slow in terms of preparing the healthcare system, stopping other travel, and COVID-19 testing in the United States, testing. The first known American deaths occurred in February and in late February President Donald Trump proposed allocating $2.5 billion to fight the outbreak. Instead, Congress approved $8.3 billion and Trump signed the Coronavirus Preparedness and Response Supplemental Appropriations Act, 2020 on March 6. Trump declared a State of emergency, national emergency on March 13. The government also purchased lar ...
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COVID-19 Pandemic In Asia
The COVID-19 pandemic began in Asia in Wuhan, Hubei, China, and has spread widely through the continent. As of , at least one case of COVID-19 had been reported in every country in Asia except Turkmenistan. The Asian countries with the highest numbers of confirmed coronavirus cases are India, South Korea, Turkey, Vietnam, and Iran. Despite being the first area of the world hit by the outbreak, the early wide-scale response of some Asian states, particularly Bhutan, Singapore, Taiwan, and Vietnam has allowed them to fare comparatively well. China was criticised for initially minimising the severity of the outbreak, but its wide-scale response has largely contained the disease since March 2020. As of July 2021, the highest numbers of deaths are recorded in India, Indonesia, Iran, and Turkey, each with more than 90,000 deaths and more than 900,000 deaths combined. However, the death toll in Iran and Indonesia are claimed to be much higher than the official figures. Per capita, ...
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COVID-19 Pandemic In Africa
The COVID-19 pandemic pandemic was confirmed to have spread to Africa on 14 February 2020, with the first confirmed case announced in COVID-19 pandemic in Egypt, Egypt. The first confirmed case in sub-Saharan Africa was announced in COVID-19 pandemic in Nigeria, Nigeria at the end of February 2020. Within three months, the virus had spread throughout the continent, as Lesotho, the last African sovereign state to have remained free of the virus, reported a case on 13 May 2020. By 26 May, it appeared that most African countries were experiencing community transmission, although testing capacity was limited. Most of the identified imported cases arrived from Europe and the United States rather than from China where the virus originated. In early June 2021, Africa faced a third wave of COVID infections with cases rising in 14 countries. By 4 July the continent recorded more than 251,000 new Covid cases, a 20% increase from the prior week and a 12% increase from the January peak. ...
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COVID-19 Pandemic In Europe
The global COVID-19 pandemic arrived in Europe with its first confirmed case in Bordeaux, France, on 24 January 2020, and subsequently spread widely across the continent. By 17 March 2020, every country in Europe had confirmed a case, and all have reported at least one death, with the exception of Vatican City. Italy was the first European country to experience a major outbreak in early 2020, becoming the first country worldwide to introduce a national lockdown. By 13 March 2020, the World Health Organization (WHO) declared Europe the epicentre of the pandemic and it remained so until the WHO announced it was overtaken by South America on 22 May. By 18 March 2020, lockdowns introduced in Europe affected more than 250 million people. Despite deployment of COVID-19 vaccines, Europe became the pandemic's epicentre once again in late 2021. On 11 January 2022, Dr. Hans Kluge, the WHO Regional Director for Europe said, "more than 50 percent of the population in the region wi ...
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COVID-19 Pandemic In South Africa
The COVID-19 pandemic in South Africa was part of the pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On 5 March 2020, Minister of Health Zweli Mkhize had confirmed the spread of the virus to South Africa, with the first known patient being a male citizen who tested positive upon his return from Italy. On 15 March 2020, the President of South Africa, Cyril Ramaphosa, declared a national state of disaster, and announced measures such as immediate travel restrictions and the closure of schools from 18 March. On 17 March, the ''National Coronavirus Command Council'' was established, "to lead the nation's plan to contain the spread and mitigate the negative impact of the coronavirus". On 23 March, a national lockdown was announced, starting on 27 March 2020. The first local death from the disease was reported on 27 March 2020. On 21 April, a 500 billion rand stimulus was announced in response ...
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COVID-19 Pandemic In The United Kingdom
The COVID-19 pandemic in the United Kingdom is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United Kingdom, it has resulted in confirmed cases, and is associated with deaths up to 26 January 2025. The virus began circulating in the country in early 2020, arriving primarily from travel elsewhere in Europe. Various sectors responded, with more widespread public health measures incrementally introduced from March 2020. The first wave was at the time one of the world's largest outbreaks. By mid-April the peak had been passed and restrictions were gradually eased. A second wave, with a new variant that originated in the UK becoming dominant, began in the autumn and peaked in mid-January 2021, and was deadlier than the first. The UK started a COVID-19 vaccination programme in early December 2020. Generalised restrictions were gradually lifted and were mostly ended by Augus ...
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COVID-19 Pandemic In Fiji
The COVID-19 pandemic in Fiji is part of the ongoing worldwide pandemic of coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (). The first case of the disease in Fiji was reported on 19 March 2020 in Lautoka. , the country has had a total of 55,009 cases as of which 2,417 are currently active and 702 deaths, with cases reported on all divisions of the country. Apart from the COVID-19 deaths, 621 COVID-19 positive patients have died from pre-existing non-COVID-19 related illnesses. In March 2021, Fiji became the first Pacific island country to receive COVID-19 vaccines through the COVAX initiative with frontline workers and first responders the first to be vaccinated. As of 2 January 2022, more than 600,000 (98%) Fijians have received their first jab of the vaccine and almost 560,000 (92%) Fijians have received their second jab and are fully vaccinated. To date, only the AstraZeneca vaccine, Moderna vaccine and the Pfizer BioNTech vaccine ...
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COVID-19 Pandemic In India
The COVID-19 pandemic in India is a part of the COVID-19 pandemic, worldwide pandemic of COVID-19, coronavirus disease 2019 () caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of , according to Indian government figures, India has the second-highest number of confirmed cases in the world (after the COVID-19 pandemic in the United States, United States) with reported cases of COVID-19 infection and the third-highest number of COVID-19 deaths (after the United States and COVID-19 pandemic in Brazil, Brazil) at deaths. In October 2021, the World Health Organization estimated 4.7 million excess deaths, both directly and indirectly related to COVID-19 to have taken place in India. The first cases of COVID-19 in India were reported on 30 January 2020 in three towns of Kerala, among three Indian medical students who had returned from Wuhan, the epicenter of the pandemic. Lockdowns were announced in Kerala on 23 March, and in the rest of the country on ...
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