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Quiz Of God
''Quiz of God'' () is a South Korean television series broadcast on cable channel OCN. It was the first medical/forensic crime investigation drama to air in Korea. The series follows genius but eccentric neurosurgeon and forensic doctor Han Jin-woo (played by Ryu Deok-hwan) and his team as they solve suspicious deaths and unravel mysteries involving rare diseases. The title refers to a local saying that rare diseases are like quizzes God gives to humans so as not to become too arrogant. The first season dealt mostly with inherited rare diseases including porphyria, phenylketonuria, muscular dystrophy, Guillain–Barré syndrome, reflex anoxic seizures and Savant syndrome. Fabry disease, Kleine–Levin syndrome and congenital insensitivity to pain with anhidrosis were featured in the second season. Series overview Cast Main * Ryu Deok-hwan as Jin-woo Han, neurosurgeon and forensic doctor * Yoon Joo-hee as Kyung-hee Kang, detective * Choi Jung-woo as Kyu-tae Jang * Park Jo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Police Procedural
The police procedural, police show, or police crime drama is a subgenre of procedural drama and detective fiction that emphasises the investigative procedure of police officers, police detectives, or law enforcement agency, law enforcement agencies as the protagonists, as contrasted with other genres that focus on non-police investigators such as private investigators (PIs). As its name implies, the defining element of a police procedural is the attempt to accurately depict law enforcement and its procedures, including police-related topics such as forensic science, Autopsy, autopsies, gathering Evidence (law), evidence, search warrants, interrogation, and adherence to legal restrictions and procedures. While many police procedurals conceal the criminal's identity until the crime is solved in the Climax (narrative), narrative climax (the so-called whodunit), others reveal the perpetrator's identity to the audience early in the narrative, making it an inverted detective story. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurosurgeon
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty that focuses on the surgical treatment or rehabilitation of disorders which affect any portion of the nervous system including the brain, spinal cord, peripheral nervous system, and cerebrovascular system. Neurosurgery as a medical specialty also includes non-surgical management of some neurological conditions. Education and context In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires a minimum period of seven years after graduating from medical school. United Kingdom In the United Kingdom, students must gain entry into medical school. The MBBS qualification (Bachelor of Medicine, Bachelor of Surgery) takes four to six years depending on the student's route. The newly qualified physician must then comple ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Korea Standard Time
South Korea has one time zone, Korea Standard Time (UTC+09:00, UTC+9), which is abbreviated KST. South Korea currently does not observe daylight saving time. From May 8 to October 9 in 1988, daylight saving time was tested to better accommodate the calendar of competitions held during the 1988 Summer Olympics in Seoul. History In 1434, inventor Jang Yeong-sil developed Korea's first automatic water clock, which Sejong the Great, King Sejong adapted as Korea's standard timekeeper. It is likely that Koreans used water clocks to keep time prior to this invention, but no concrete records of them exist. In 1437, Jang Yeong-sil, with Jeong Cho, created a bowl-shaped sundial called the ''angbu ilgu'' (), which King Sejong had placed in public so anyone could use it. In 1908, the Korean Empire adopted a standard time, GMT+08:30. In 1912, during the Korea under Japanese rule, Japanese occupation of Korea, the Governor-General of Korea changed standard time to GMT+09:00 to align with Ja ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anhidrosis
Hypohidrosis is a medical condition in which a person exhibits diminished sweating in response to appropriate stimuli. In contrast with hyperhidrosis, which is a socially troubling yet often benign condition, the consequences of untreated hypohidrosis include hyperthermia, heat stroke and death. An extreme case of hypohidrosis in which there is a complete absence of sweating and the skin is dry is termed anhidrosis. The condition is also known as adiaphoresis, ischidrosis, oligidria, oligohidrosis and sweating deficiency. Causes The causes are the following: Diagnosis Sweat is readily visualized by a topical indicator such as iodinated starch ( Minor test) or sodium alizarin sulphonate, both of which undergo a dramatic colour change when moistened by sweat. A thermoregulatory sweat test can evaluate the body’s response to a thermal stimulus by inducing sweating through a hot box (also called a ''hot room''), a thermal blanket, or physical exercise. Failure of the topical indic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Insensitivity To Pain
Congenital insensitivity to pain (CIP), also known as congenital analgesia, is an inability for a person to feel physical pain due to various rare genetic conditions. CIP is caused by genetic mutations that affect the development or function of nociceptors, the sensory neurons in the brain responsible for recognizing tissue damage. Common symptoms include damage to the oral cavity, repeated bone fractures, and sometimes the inability to sweat. Some forms of CIP are also correlated with intellectual disabilities, learning disabilities, or attention deficit hyperactivity disorder (ADHD). Hereditary sensory autonomic neuropathies (HSAN) fall under the umbrella of CIP. Methods of treatment are still being explored. The epidemiology of CIP is unclear, given the relatively low number of reported cases. Classification The term congenital analgesia, also known as CIP, was first coined in the 1970s or 1980s. CIP is an umbrella term that describes a collection of rare genetic disorders th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kleine–Levin Syndrome
Kleine–Levin syndrome (KLS) is a rare neurological disorder characterized by persistent episodic hypersomnia accompanied by cognitive and behavioral changes. These changes may include disinhibition (failure to inhibit actions or words), sometimes manifested through hypersexuality, hyperphagia or emotional lability, and other symptoms, such as derealization. Patients generally experience recurrent episodes of the condition for more than a decade, which may return at a later age. Individual episodes generally last more than a week, sometimes lasting for months. The condition greatly affects the personal, professional, and social lives of those with KLS. The severity of symptoms and the course of the syndrome vary between those with KLS. Patients commonly have about 20 episodes over about a decade. Several months may elapse between episodes. The onset of the condition usually follows a viral infection (72% of patients); several different viruses have been observed to trigger KLS. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fabry Disease
Fabry disease, also known as Anderson–Fabry disease, is a rare genetic disease that can affect many parts of the body, including the kidneys, heart, brain, and skin. Fabry disease is one of a group of conditions known as lysosomal storage diseases. The genetic mutation that causes Fabry disease interferes with the function of an enzyme that processes biomolecules known as sphingolipids, leading to these substances building up in the walls of blood vessels and other organs. It is inherited in an X-linked manner. Fabry disease is sometimes diagnosed using a blood test that measures the activity of the affected enzyme called alpha-galactosidase, but genetic testing is also sometimes used, particularly in females. The treatment for Fabry disease varies depending on the organs affected by the condition, and the underlying cause can be addressed by replacing the enzyme that is lacking. The first descriptions of the condition were made simultaneously by dermatologist Johannes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Savant Syndrome
Savant syndrome ( , ) is a phenomenon where someone demonstrates exceptional aptitude in one domain, such as art or mathematics, despite significant social or intellectual impairment. Those with the condition generally have a neurodevelopmental condition, such as autism, or have experienced a brain injury. About half of cases are associated with autism, and these individuals may be known as autistic savants. The other half often have some form of central nervous system injury or disease. While the condition usually becomes apparent in childhood, some cases develop later in life. It is not recognized as a mental disorder within the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), as it relates to parts of the brain healing or restructuring. Savant syndrome is estimated to affect around one in a million people. The condition affects more males than females, at a ratio of 6:1. The first medical account of the condition was in 1783. It is estima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reflex Asystolic Syncope
Reflex asystolic syncope (RAS) is a form of syncope encountered mainly, but not exclusively, in young children. Reflex anoxic seizures are not epileptic seizures or epilepsy. This is usually a consequence of a reduction in cerebral perfusion by oxygenated blood. It can be a result of either a sudden reduction in the blood flow to the brain, a drop in the oxygen content of the blood supplying the brain, or a combination of the two. Syncope can have different meanings ranging from transient loss of consciousness, usually accompanied by a decrease or loss in postural tone (the principal manifestations of "simple faints"), to tonic and myoclonic events and nonepileptic spasms. Signs and symptoms A minor bump to the head is the most commonly reported precipitant. Usually the toddler trips and falls; the child's caregiver may hear the bump. Most commonly, the child does not cry, although some parents give descriptions of the child "trying to cry" (Stephenson 1978), or there may be a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guillain–Barré Syndrome
Guillain–Barré syndrome (GBS) is a rapid-onset Paralysis, muscle weakness caused by the immune system damaging the peripheral nervous system. Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. The symptoms may develop over hours to a few weeks. During the acute phase, the disorder can be life-threatening, with about 15% of people developing respiratory system, respiratory muscle weakness requiring mechanical ventilation. Some are affected by dysautonomia, changes in the function of the autonomic nervous system, which can lead to dangerous abnormalities in heart rate and blood pressure. Although the cause is unknown, the underlying mechanism involves an autoimmune disorder in which the body's immune system mistakenly attacks the peripheral nerves and damages their myelin insulation. Sometimes this im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muscular Dystrophy
Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Some types are also associated with problems in other human organs, organs. Over 30 different disorders are classified as muscular dystrophies. Of those, Duchenne muscular dystrophy (DMD) accounts for approximately 50% of cases and affects males beginning around the age of four. Other relatively common muscular dystrophies include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy, whereas limb–girdle muscular dystrophy and congenital muscular dystrophy are themselves groups of several – usually extremely rare – genetic disorders. Muscular dystrophies are caused by mutations in genes, usually those involved in making ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylketonuria
Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine. Untreated PKU can lead to intellectual disability, seizures, behavioral problems, and mental disorders. It may also result in a musty smell and lighter skin. A baby born to a mother who has poorly treated PKU may have heart problems, a small head, and low birth weight. Phenylketonuria is an inherited genetic disorder. It is caused by mutations in the '' PAH'' gene, which can result in inefficient or nonfunctional phenylalanine hydroxylase, an enzyme responsible for the metabolism of excess phenylalanine. This results in the buildup of dietary phenylalanine to potentially toxic levels. It is autosomal recessive, meaning that both copies of the gene must be mutated for the condition to develop. The two main types are classic PKU and variant PKU, depending on whether any enzyme function remains. Those with one copy of a mutated gene typically do not ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
