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Quinolizidine Alkaloid
Quinolizidine (norlupinane, octahydro-2''H''-quinolizine) is a nitrogen-containing heterocyclic compound. Some alkaloids (e.g. cytisine and sparteine) are derivatives of quinolizidine. Quinolizidine alkaloids Quinolizidine alkaloids, such as nupharine and related chemicals, can be found in ''Nymphaea lotus'' and other species in the family Nymphaeaceae. Quinolizidine alkaloids are also found in genistoid legumes Legumes are plants in the pea family Fabaceae (or Leguminosae), or the fruit or seeds of such plants. When used as a dry grain for human consumption, the seeds are also called pulses. Legumes are grown agriculturally, primarily for human consu .... External links * * Synthesis: {{heterocyclic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterocyclic Compound
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic organic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of organic heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of organic heterocyclic chemistry focuses especially on organic unsaturated derivatives, and the preponderance of work and applications involves unstrained organic 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of organic heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of py ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytisine
Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as '' Laburnum'' and '' Cytisus'' of the family Fabaceae. It has been used medically to help with smoking cessation. It has been found effective in several randomized clinical trials, including in the United States and New Zealand, and is being investigated in additional trials in the United States and a non-inferiority trial in Australia in which it is being compared head-to-head with the smoking cessation aid varenicline (sold in the United States as Chantix). It has also been used entheogenically via mescalbeans by some Native American groups, historically in the Rio Grande Valley predating even peyote. Sources Cytisine is extracted from the seeds of '' Cytisus laburnum'' L. (Golden Rain acacia), and is found in several genera of the subfamily Faboideae of the family Fabaceae, including '' Laburnum'', '' Anagyris'', '' Thermopsis'', '' C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sparteine
Sparteine is a class 1a antiarrhythmic agent and sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in '' Lupinus mutabilis'', and is thought to chelate the bivalent metals calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughan Williams classification of antiarrhythmic drugs. It is also used as a chiral ligand in organic chemistry, especially in syntheses involving organolithium reagents. Biosynthesis Sparteine is a lupin alkaloid containing a tetracyclic bis-quinolizidine ring system derived from three C5 chains of lysine, or more specifically, -lysine. The first intermediate in the biosynthesis is cadaverine, the decarboxylation product of lysine catalyzed by the enzyme lysine decarboxylase (LDC). Three units of cadaverine are used to form the quinolizidine skeleton. The mechanism of formation has been studied enzymatically, as well as w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nymphaea Lotus
''Nymphaea lotus'', the white Egyptian lotus, tiger lotus, white lotus, or Egyptian water-lily, is a flowering plant of the family Nymphaeaceae. Distribution It grows in various parts of East Africa and Southeast Asia. ''Nymphaea lotus'' var. ''thermalis'' was believed to be a Tertiary relict variety endemic to the thermal waters of Europe, for example, the Peţa River in Romania. DNA analysis has concluded that ''Nymphaea lotus'' var. ''thermalis'' lacks distinctiveness from ''Nymphaea lotus'' and therefore cannot be classified as a relic population.Laczkó, L., Lukács, B. A., Mesterházy, A., Molnár, A., & Sramkó, G. (2019)"Is ''Nymphaea lotus'' var. ''thermalis'' a Tertiary relict in Europe?."Aquatic Botany, 155, 1-4. Cultivation It was introduced into Western cultivation in 1802 by Loddiges Nursery. Eduard Ortgies crossed ''Nymphaea lotus'' (''N. dentata'') with '' Nymphaea pubescens'' (''N. rubra'') to produce the first ''Nymphaea'' hybrid, illustrated in ''Flore des ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genistoids
The Genistoids are one of the major radiations in the plant family Fabaceae. Members of this phylogenetic clade are primarily found in the Southern hemisphere. Some genera are pollinated by birds. The genistoid clade is consistently resolved as monophyletic in molecular phylogenetic analyses. It is estimated to have arisen 56.4 ± 0.2 million years ago (in the Paleocene). A node-based definition for the genistoids is: "the MRCA of '' Poecilanthe parviflora'' and ''Lupinus argenteus''." One morphological synapomorphy has been tentatively identified: production of quinolizidine alkaloids. Some genera also accumulate pyrrolizidine. A new genus, to be segregated from '' Clathrotropis'', has also been proposed to occupy an undetermined position within the genistoid clade. Core Genistoids The core genistoids, also known as the genistoids ''sensu stricto'', comprise most of the tribes of the genistoids ''sensu lato'', and are found mainly in Africa and Eurasia. This subclade is al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legumes
Legumes are plants in the pea family Fabaceae (or Leguminosae), or the fruit or seeds of such plants. When used as a dry grain for human consumption, the seeds are also called pulses. Legumes are grown agriculturally, primarily for human consumption, but also as livestock forage and silage, and as soil-enhancing green manure. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces (opens along a seam) on two sides. Most legumes have symbiotic nitrogen-fixing bacteria, Rhizobia, in structures called root nodules. Some of the fixed nitrogen becomes available to later crops, so legumes play a key role in crop rotation. Terminology The term ''pulse'', as used by the United Nations' Food and Agriculture Organization (FAO), is reserved for legume crops harvested solely for the dry seed. This excludes green beans and green peas, which are considered vegetable crops. Also excluded are seeds that are main ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
