|
Psoralea Corylifolia
''Cullen corylifolium'', Synonym (taxonomy), synonym ''Psoralea corylifolia'', (babchi) is a plant used in Indian and Chinese traditional medicine. The seeds of this plant contain a variety of coumarins, including psoralen. Used as a dietary supplement, ''Cullen corylifolium'' is of no clinical benefit and can cause potentially fatal herb-induced liver injury. Etymology ''Corylifolium'' comes from similarity of the leaves to those of ''Corylus'', a genus of tree in northern world regions, such as Sweden. Description ''Cullen corylifolium'' grows 50–90 cm tall and is an annual plant. It has pale-purple flowers in short, condensed, axillary spikes. Its corolla is pale purple. Flowers one-seeded fruits. The most distinctive feature is the occurrence of minute brown glands which are immersed in surface tissue on all parts of the plant, giving it a distinctive and pleasant fragrance. Habitat and distribution ''Cullen corylifolium'' is native to north-east Afrotropical realm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl Linnaeus
Carl Linnaeus (23 May 1707 – 10 January 1778), also known after ennoblement in 1761 as Carl von Linné,#Blunt, Blunt (2004), p. 171. was a Swedish biologist and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern Taxonomy (biology), taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was the son of a curate and was born in Råshult, in the countryside of Småland, southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In the 1750s and 1760s, he co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bakuchiol
Bakuchiol is a meroterpenoid (a chemical compound having a partial terpenoid structure) in the class terpenophenol. It was first isolated in 1966 by Mehta et al. from ''Psoralea corylifolia'' seed and was called Bakuchiol based on the Sanskrit name of the plant, Bakuchi. Bakuchiol is a meroterpene phenol abundant in and mainly obtained from the seeds of the Psoralea corylifolia plant, which is widely used in Indian Ayurveda to treat a variety of diseases. It has also been isolated from other plants, such as P. grandulosa, P. drupaceae, Ulmus davidiana, Otholobium pubescens, Long pepper, Piper longum and Aerva sangulnolenta Blum. Even though the first complete synthesis of Bakuchiol was described in 1973, its first commercial use in topical applications did not occur until 2007 when it was introduced to the market under the trade name Sytenol A by Sytheon Ltd. It has been reported to have anticancer activity in preclinical models, possibly due to its structural similarity with res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meroterpene
A meroterpene (or meroterpenoid) is a chemical compound having a partial terpenoid structure. Examples Terpenophenolics Terpenophenolics are compounds that are part terpenes, part natural phenols. Plants in the genus ''Humulus'' and ''Cannabis'' produce terpenophenolic metabolites, such as humulone and tetrahydrocannabinol respectively. Other examples of terpenophenolics from plants include bakuchiol and lapachol. The antibiotic marinone produced by marine bacteria is another example. Terpenophenolics can also be isolated from animals. The terpenophenolics methoxyconidiol, epiconicol and didehydroconicol, isolated from the ascidian ''Aplidium ''Aplidium'' is a genus of colonial sea squirts, tunicates in the family Polyclinidae. There are about 188 species in the genus found in shallow waters around the world. Species The following species are listed in this genus according to the W ... aff. densum'', show antiproliferative activity. References {{orga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angelicin
Angelicin is the parent compound in a family of naturally occurring organic compounds known as the angular furanocoumarins. Structurally, it can be considered as benzapyra-2-one fused with a furan moiety in the 7,8-position. Angelicin is commonly found in certain Apiaceae and Fabaceae plant species such as '' Bituminaria bituminosa''. It has a skin permeability coefficient (Log''Kp'') of -2.46. The maximum absorption is observed at 300 nm. The 1HNMR spectrum is available; the infrared and mass spectra of angelicin can be found in thidatabase The sublimation of angelicin occurs at 120 °C and the pressure of 0.13 Pa. Angelicin is a coumarin. History and etymology Humans have used plants rich in angelicin for centuries. The earliest known record dates back to 3000 BC when ancient Egyptians applied the oil and sap of local ''Apiaceae'' species exposing their skin to sunlight to cure vitiligo. In meantime, tribes in India used '' Psoralea corylifolia'' which contained psor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psoralidin
Psoralidin is a natural phenolic compound found in the seeds of ''Psoralea corylifolia''. Chemical synthesis Psoralidin production starts with a based catalyzed condensation between phenyl acetate and acid chloride. To form the ring of psoralidin, an intramolecular cyclization occurs, finished off by a microwave assisted cross metathesis reaction. Pharmacology Psoralidin inhibits forskolin-induced corticotrophin releasing factor gene transcription. Recently, it has shown activity ''in vitro'' against gastric, colon, prostate, and breast cancer lines. It has the capability to inhibit protein tyrosine phosphatase 1B, a key metabolite involved in insulin signaling. Psoralidin has shown positive results in the forced swim test, a mouse model of antidepressant activity. Psoralidin raised 5-hydroxytryptamine and 5-hydroxyindoleacetic acid levels in the brain. Dopamine levels changed as well as a result of psoralidin consumption. Stress hormones in mice such as serum cortic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
