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Papaver Bracteatum
''Papaver bracteatum'', also known as the Iranian poppy or Persian poppy and the great scarlet poppy (first described by Dr. N. Saharghi and Iraj Lalezari ''Nature'' 213, 1244, 1967 doi:10.1038/2131244a0 ) is a sturdy hardy perennial poppy with large deep red flowers up to 8 inches (20 cm) in diameter on stiff stalks up to 4 feet (1.22 metres) high with a prominent black spot near the base of the petals. It is closely related to the commonly cultivated oriental poppy, ''Papaver orientale'' and is sometimes recorded as the varietal form ''Papaver orientale'' var. ''bracteatum''. Uses This species is grown to produce thebaine, which is commercially converted to codeine and semi-synthetic opiates including hydrocodone, hydromorphone, oxycodone, and oxymorphone. ''Papaver bracteatum'' does not contain morphine, codeine or any other narcotic alkaloids in significant amounts. Oripavine has been reported in minute traces but would not exert a relevant activity. In the United ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Lindley
John Lindley Fellow of the Royal Society, FRS (5 February 1799 – 1 November 1865) was an English botanist, gardener and orchidology, orchidologist. Early years Born in Old Catton, Catton, near Norwich, England, John Lindley was one of four children of George and Mary Lindley. George Lindley was a nurseryman and pomologist and ran a commercial nursery garden. Although he had great horticultural knowledge, the undertaking was not profitable and George lived in a state of indebtedness. As a boy he would assist in the garden and also collected wild flowers he found growing in the Norfolk countryside. Lindley was educated at Norwich School. He would have liked to go to university or to buy a commission in the army but the family could not afford either. He became Belgium, Belgian agent for a London seed merchant in 1815. At this time Lindley became acquainted with the botanist William Jackson Hooker who allowed him to use his botanical library and who introduced him to Sir Joseph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are multiple methods used to administer morphine: oral; sublingual administration, sublingual; via inhalation; intramuscular, injection into a muscle, Subcutaneous injection, injection under the skin, or injection into the spinal cord area; transdermal; or via rectal administration, rectal suppository. It acts directly on the central nervous system (CNS) to induce analgesia and alter perception and emotional response to pain. Physical and psychological dependence and tolerance may develop with repeated administration. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during Childbirth, labor. Its maximum effect is reached after about 20 minutes when administ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bentley Compounds
Bentley Motors Limited is a British designer, manufacturer and marketer of luxury cars and SUVs. Headquartered in Crewe, England, the company was founded by W. O. Bentley (1888–1971) in 1919 in Cricklewood, North London, and became widely known for winning the 24 Hours of Le Mans in 1924, 1927, 1928, 1929, 1930 and 2003. Bentley has been a subsidiary of the Volkswagen Group since 1998 and consolidated under VW's premium brand arm Audi since 2022. Prominent models extend from the historic sports-racing Bentley 4½ Litre and Bentley Speed Six; the more recent Bentley R Type Continental, Bentley Turbo R, and Bentley Arnage; to its current model line, including the Flying Spur, Continental GT and Bentayga which are marketed worldwide, with China as its largest market as of November 2012. Today most Bentley models are assembled at the company's Crewe factory, with a small number assembled at Volkswagen's Dresden factory, Germany, and with bodies for the Con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heroin
Heroin, also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the Opium, dried latex of the Papaver somniferum, opium poppy; it is mainly used as a recreational drug for its euphoric effects. Heroin is used medically in several countries to Pain reliever, relieve pain, such as during childbirth or a heart attack, as well as in opioid replacement therapy. Medical-grade diamorphine is used as a pure Hydrochloride, hydrochloride salt. Various white and brown powders sold illegally around the world as ''heroin'' are routinely diluted with cutting agents. Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin. Heroin is typically Drug injection, injected, usually into a vein, but it can also be snorted, smoked, or inhaled. In a clinical context, the route of administration is mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papaver Somniferum
''Papaver somniferum'', commonly known as the opium poppy or breadseed poppy, is a species of flowering plant in the family Papaveraceae. It is the species of plant from which both opium and poppy seeds are derived and is also a valuable ornamental plant grown in gardens. Its native range was the eastern Mediterranean region, but has since been obscured by widespread introduced species, introduction and Horticulture, cultivation since ancient times to the present day. It is now Naturalisation (biology), naturalized across much of the world with temperate climates. This poppy is grown as an agricultural crop on a large scale, for one of three primary purposes: to produce poppy seeds, to produce opium (for use mainly by the pharmaceutical industry), and to produce other alkaloids (mainly thebaine and oripavine) that are processed by pharmaceutical companies into drugs such as hydrocodone and oxycodone. Each of these goals has special breeds that are targeted at one of these busine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Turkey
Turkey, officially the Republic of Türkiye, is a country mainly located in Anatolia in West Asia, with a relatively small part called East Thrace in Southeast Europe. It borders the Black Sea to the north; Georgia (country), Georgia, Armenia, Azerbaijan, and Iran to the east; Iraq, Syria, and the Mediterranean Sea to the south; and the Aegean Sea, Greece, and Bulgaria to the west. Turkey is home to over 85 million people; most are ethnic Turkish people, Turks, while ethnic Kurds in Turkey, Kurds are the Minorities in Turkey, largest ethnic minority. Officially Secularism in Turkey, a secular state, Turkey has Islam in Turkey, a Muslim-majority population. Ankara is Turkey's capital and second-largest city. Istanbul is its largest city and economic center. Other major cities include İzmir, Bursa, and Antalya. First inhabited by modern humans during the Late Paleolithic, present-day Turkey was home to List of ancient peoples of Anatolia, various ancient peoples. The Hattians ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Office Of Management And Budget
The Office of Management and Budget (OMB) is the largest office within the Executive Office of the President of the United States (EOP). The office's most prominent function is to produce the president's budget, while it also examines agency programs, policies, and procedures to see whether they comply with the president's policies and coordinates inter-agency policy initiatives. Russell Vought is the current director of the OMB since February 2025. History The Bureau of the Budget, OMB's predecessor, was established in 1921 as a part of the United States Department of the Treasury, Department of the Treasury by the Budget and Accounting Act of 1921, which President Warren G. Harding signed into law. The Bureau of the Budget was moved to the Executive Office of the President of the United States, Executive Office of the President in 1939 and was run by Harold D. Smith during the government's rapid expansion of spending during World War II. James L. Sundquist, a staffer at the B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Nixon
Richard Milhous Nixon (January 9, 1913April 22, 1994) was the 37th president of the United States, serving from 1969 until Resignation of Richard Nixon, his resignation in 1974. A member of the Republican Party (United States), Republican Party, he previously served as the 36th Vice President of the United States, vice president under President Dwight D. Eisenhower from 1953 to 1961, and also as a United States House of Representatives, representative and United States Senate, senator from California. Presidency of Richard Nixon, His presidency saw the reduction of U.S. involvement in the Vietnam War, ''détente'' with the Soviet Union and China, the Apollo 11 Moon landing, and the establishment of the United States Environmental Protection Agency, Environmental Protection Agency and Occupational Safety and Health Administration. Nixon's second term ended early when he became the only U.S. president to resign from office, as a result of the Watergate scandal. Nixon was born ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oripavine
Oripavine is an opioid and the major metabolite of thebaine. It is the precursor to the semi-synthetic compounds etorphine and buprenorphine. Although this chemical compound has analgesic potency comparable to morphine, it is not used clinically due to severe adverse effects and a low therapeutic index. Being a precursor to a series of extremely strong opioids, oripavine is a controlled substance in some jurisdictions. Pharmacological properties Oripavine possesses an analgesic potency comparable to morphine; however, it is not clinically useful due to severe toxicity and low therapeutic index. In both mice and rats, toxic doses caused tonic-clonic seizures followed by death, similar to thebaine. Oripavine has a potential for dependence which is significantly greater than that of thebaine but slightly less than that of morphine. Bridged derivatives (The Bentley compounds) Of much greater relevance are the properties of the orvinols, a large family of semi-synthet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxymorphone
Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes; after oral administration it begins after about 30 minutes and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets. The elimination half-life of oxymorphone is much faster intravenously, and as such, the drug is most commonly used orally. Like oxycodone, which metabolizes to oxymorphone, oxymorphone has a high abuse potential. Oxymorphone was developed in Germany in 1914. It was patented in 1955 and approved for medical use in 1959. In June 2017 the FDA asked Endo Pharmaceuticals to remove its product from the US market. This was in part due to the opioid epidemic in the US, and the fact that a 2012 reformulation failed to stop illicit injection of the drug. Endo responded by voluntarily removing Opana ER from the market ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iraj Lalezari
Iraj Lalezari (1930–2019) was an Iranian academic of Jewish origin. His study fields were organic chemistry and pharmacology. He left Iran in 1979 following the regime change in the country and settled in the US where he continued his academic studies. Early life and education Lalezari was born in Hamadan on 4 July 1930. He was the eldest of four siblings. He received a degree in pharmacology from the University of Tehran. He obtained his PhD in pharmacology from his alma mater in 1951. He also received a PhD in organic chemistry from the University of Sorbonne in 1953. He carried out his post-doctorate studies in organic chemistry at the same institution in 1954. Career and activities Following his graduation, Lalezari joined the University of Tehran where he served as the chair of the chemistry department (1970–1978) and the dean of the pharmacology faculty (1973–1979). In 1964 he was promoted to a professorship in organic chemistry. He was named as the chair of the Irani ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
