Nipples
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Nipples
The nipple is a raised region of tissue on the surface of the breast from which, in lactating females, milk from the mammary gland leaves the body through the lactiferous ducts to nurse an infant. The milk can flow through the nipple passively, or it can be ejected by smooth muscle contractions that occur along with the ductal system. The nipple is surrounded by the areola, which is often a darker colour than the surrounding skin. Male mammals also have nipples but without the same level of function or prominence. A nipple is often called a ''teat'' when referring to non-humans. "Nipple" or "teat" can also be used to describe the flexible mouthpiece of a baby bottle. In humans, the nipples of both males and females can be sexually stimulated as part of sexual arousal. In many cultures, female nipples are sexualized, or regarded as sex objects and evaluated in terms of their physical characteristics and sex appeal. Etymology The word "nipple" most likely originates as a dimin ...
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Areola
The human areola (''areola mammae'', or ) is the pigmented area on the breast around the nipple. More generally, an areola is a small circular area on the Human body, body with a different histology from the surrounding Tissue (biology), tissue, or other small circular areas such as an inflamed region of skin. The mature human female nipple has several small openings arranged radially around the tip of the lactiferous ducts, from which milk is released during lactation. The other small openings in the areola are sebaceous glands, also known as Areolar gland, areolar glands. Shade The areolae can range from pink to red to brown to dark brown or nearly black, but generally tend to be paler among people with lighter skin tones and darker among people with darker skin tones. A reason for the differing color may be to make the nipple area more visible to the infant. Hyperpigmentation occurs in most women during the second stage of pregnancy, leading to a temporarily darker shade. ...
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Proto-Germanic
Proto-Germanic (abbreviated PGmc; also called Common Germanic) is the linguistic reconstruction, reconstructed proto-language of the Germanic languages, Germanic branch of the Indo-European languages. Proto-Germanic eventually developed from Germanic parent language, pre-Proto-Germanic into three Germanic branches during the fifth century BC to fifth century AD: West Germanic languages, West Germanic, East Germanic languages, East Germanic and North Germanic languages, North Germanic. North Germanic remained in language contact, contact with the other branches over a considerable time, especially with the Ingvaeonic languages (including History of English, English), which arose from West Germanic dialects, and had remained in contact with the Proto-Norse language, Norse. A defining feature of Proto-Germanic is the completion of the process described by Grimm's law, a set of sound changes that occurred between its status as a dialect of Proto-Indo-European language, Proto-Indo- ...
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Pacinian Corpuscle End-organs
The Pacinian corpuscle (also lamellar corpuscle, or Vater–Pacini corpuscle) is a low-threshold mechanoreceptor responsive to vibration or pressure, found in the skin and other internal organs. In the skin it is one of the four main types of cutaneous receptors. The corpuscles are present in skin notably on both surfaces of the hands and feet, arms, and neck. Pacinian corpuscles are also found on bone periosteum, joint capsules, the pancreas and other internal organs, the breast, genitals, and lymph nodes. Pacinian corpuscles are rapidly adapting mechanoreceptors. As phasic receptors they respond quickly but briefly to a stimulus with the response diminishing even when the stimulus is maintained. They primarily respond to vibration, and deep pressure. They are especially sensitive to high-frequency vibrations. Groups of corpuscles sense pressure changes (such as on grasping or releasing an object). They are additionally crucially involved in proprioception. The vibrational r ...
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Meissner Corpuscle End-organ
Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner. This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure. In particular, they have their highest sensitivity (lowest threshold) when sensing vibrations between 10 and 50 hertz. They are rapidly adaptive receptors. They are most concentrated in thick hairless skin, especially at the finger pads. Structure Tactile corpuscles are encapsulated myelinated nerve endings, surrounded by Schwann cells. The encapsulation consists of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsule. The corpuscle is 30–140 μm in length and 40–60 μm in diameter. A single nerve fiber meanders between the lamellae and throughout the corpuscle. Location They are distributed on various areas of the skin, but concentrated in areas especially sensitive to li ...
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Ruffini Corpuscle End-organ
The bulbous corpuscle, Ruffini ending or Ruffini corpuscle is a slowly adapting mechanoreceptor A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are located on sensory neurons that convert mechanical pressure into action potential, electrical signals tha ... located in the cutaneous tissue between the dermal papillae and the hypodermis. It is named after Angelo Ruffini. Structure Ruffini corpuscles are enlarged dendritic endings with elongated capsules. Function This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement. They are at the highest density around the fingernails where they act in monitoring slippage of objects along the surface of the skin, allowing modulation of grip on an object. Ruffini corpuscles respond to sustained pressure and show very little adaptation. Ruffinian endings are ...
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Merkel Corpuscle End-organ
Merkel nerve endings (also Merkel's disks, or Merkel tactile endings) are mechanoreceptors situated in the basal epidermis as well as around the apical ends or some hair follicles. They are slowly adapting. They have small receptive fields measuring some millimeters in diameter. Most are associated with fast-conducting large myelinated axons. A single afferent nerve fibre branches to innervate up to 90 such endings. Merkel nerve endings respond to light touch. They respond to sustained pressure, and are sensitive to edges of objects. Their exact functions remain controversial. The Merkel nerve endings consist of a nerve ending associated with a flattened epithelial cell (Merkel cell); both the nerve ending and Merkel cell are independently mechanosensitive. The Merkel cell expresses the PIEZO2 mechanosensitive ion channels; mechanical activation of the channel causes depolarisation of the Merkel cell and consequent release of serotonin into a synapse with the associated nerve ...
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Mechanoreceptor
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are located on sensory neurons that convert mechanical pressure into action potential, electrical signals that, in animals, are sent to the central nervous system. Vertebrate mechanoreceptors Cutaneous mechanoreceptors Cutaneous mechanoreceptors respond to mechanical stimuli that result from physical interaction, including pressure and vibration. They are located in the skin, like other cutaneous receptors. They are all innervated by Aβ fibers, except the mechanorecepting free nerve endings, which are innervated by A delta fiber, Aδ fibers. Cutaneous mechanoreceptors can be categorized by what kind of sensation they perceive, by the rate of adaptation, and by morphology. Furthermore, each has a different receptive field. By sensation * The Slowly Adapting type 1 (SA1) mechanoreceptor, with the Merkel corpuscle end-organ (also known as M ...
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Integumentary
The integumentary system is the set of organs forming the outermost layer of an animal's body. It comprises the skin and its appendages, which act as a physical barrier between the external environment and the internal environment that it serves to protect and maintain the body of the animal. Mainly it is the body's outer skin. The integumentary system includes skin, hair, Scale (zoology), scales, feathers, Hoof, hooves, claws, and Nail (anatomy), nails. It has a variety of additional functions: it may serve to maintain water balance, protect the deeper tissues, excrete wastes, and regulate Core temperature, body temperature, and is the attachment site for sensory receptors which detect pain, sensation, pressure, and temperature. Structure Skin The skin is one of the largest organs of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5 to 2 m2 of surface area. The skin (integument) is a composite organ, made up of at least two maj ...
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Nerve
A nerve is an enclosed, cable-like bundle of nerve fibers (called axons). Nerves have historically been considered the basic units of the peripheral nervous system. A nerve provides a common pathway for the Electrochemistry, electrochemical nerve impulses called action potentials that are transmitted along each of the axons to peripheral organs or, in the case of sensory nerves, from the periphery back to the central nervous system. Each axon is an extension of an individual neuron, along with other supportive cells such as some Schwann cells that coat the axons in myelin. Each axon is surrounded by a layer of connective tissue called the endoneurium. The axons are bundled together into groups called Nerve fascicle, fascicles, and each fascicle is wrapped in a layer of connective tissue called the perineurium. The entire nerve is wrapped in a layer of connective tissue called the epineurium. Nerve cells (often called neurons) are further classified as either Sensory neuron, sens ...
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Eutheria
Eutheria (from Greek , 'good, right' and , 'beast'; ), also called Pan-Placentalia, is the clade consisting of Placentalia, placental mammals and all therian mammals that are more closely related to placentals than to marsupials. Eutherians are distinguished from non-eutherians by various phenotypic traits of the feet, ankles, jaws and teeth. All extant eutherians lack epipubic bones, which are present in all other living mammals (marsupials and monotremes). This allows for expansion of the abdomen during pregnancy, though epipubic bones are present in many primitive eutherians. Eutheria was named in 1872 by Theodore Gill; in 1880, Thomas Henry Huxley defined it to encompass a more broadly defined group than Placentalia. The earliest unambiguous eutherians are known from the Early Cretaceous Yixian Formation of China, dating around 120 million years ago. Two tribosphenic mammals, ''Durlstodon'' and ''Durlstotherium'' from the Berriasian age (~145–140 million years ago) of t ...
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Marsupial
Marsupials are a diverse group of mammals belonging to the infraclass Marsupialia. They are natively found in Australasia, Wallacea, and the Americas. One of marsupials' unique features is their reproductive strategy: the young are born in a relatively undeveloped state and then nurtured within a pouch on their mother's abdomen. Extant marsupials encompass many species, including Kangaroo, kangaroos, Koala, koalas, Opossum, opossums, Phalangeriformes, possums, Tasmanian devil, Tasmanian devils, Wombat, wombats, Wallaby, wallabies, and Bandicoot, bandicoots. Marsupials constitute a clade stemming from the last common ancestor of extant Metatheria, which encompasses all mammals more closely related to marsupials than to Placentalia, placentals. The evolutionary split between placentals and marsupials occurred 125-160 million years ago, in the Middle Jurassic-Early Cretaceous period. Presently, close to 70% of the 334 extant marsupial species are concentrated on the Australian ...
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Skin
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/ os clitoris. All mammals have some hair on their skin, even marine mammals like whales, ...
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