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Neuromedin U Receptor
The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene (, ). Selective Ligands Neuromedin U is an agonist at both the NMU1 and NMU2 subtypes, while neuromedin S is selective for NMU2, and is a more potent agonist at this subtype than neuromedin U. Several other peptide and non-peptide ligands are also available for the NMU receptors. Agonists ;Non-selective * Neuromedin U * non-peptide NMU modulators Kajino M, Hinuma S, Tarui N, Yamashita T, Nakayama Y. Receptor regulators. European Patent EP 1559428 A1. Published 03.08.2005 ;NMU2 selective * Neuromedin S Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian r ... Antagonists ; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin U Receptor 1
Neuromedin-U receptor 1 is a protein that in humans is encoded by the ''NMUR1'' gene. See also * Neuromedin U receptor * Limostatin Limostatin (from Limos, the Greek goddess of starvation) is a peptide hormone found in Drosophila melanogaster that suppresses the production and release of Insulin. The hormone is important in adaptation to starvation conditions, and represents ... References Further reading * * * * * * * External links * * * G protein-coupled receptors {{transmembranereceptor-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin U Receptor 2
Neuromedin-U receptor 2 is a protein that in humans is encoded by the ''NMUR2'' gene. Ligands Agonists * synephrine See also * Neuromedin U receptor The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene (, ). Selective Ligands Neur ... References Further reading * * * * * * * * * External links * G protein-coupled receptors {{transmembranereceptor-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
G-protein Coupled Receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Text was copied from this source, which is available under Attribution 2.5 Generic (CC BY 2.5) license. Ligands can bind either to extracellular N-terminus and loops (e.g. glutamate receptors) or to the binding site within transmembrane helices (Rhodopsin-like family). They are all activated by agonists although a spontaneous auto-activation of an empty receptor can also be observed. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin U
Neuromedin may refer to: * Neuromedin B * Neuromedin N * Neuromedin S Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian r ... * Neuromedin U {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin S
Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian rhythm and also has appetite suppressant effects, as well as regulating the release of several other peptide hormones including vasopressin, luteinizing hormone, and oxytocin. See also * Neuromedin U receptor The neuromedin U receptors are two G-protein coupled receptor G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked ... References {{Neuropeptides Neuropeptides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacological Reviews
''Pharmacological Reviews'' is a quarterly peer-reviewed scientific journal publishing review articles on all aspects of pharmacology and related topics. It is published by the American Society for Pharmacology and Experimental Therapeutics. The editor-in-chief is Eric Barker ( Purdue College of Pharmacy). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 25.468. , this title was known for having the "most exhaustive surveys" among six titles devoted to reviews in the pharmacology discipline. References External links * Pharmacology journals Publications established in 1949 Quarterly journals English-language journals Academic journals published by learned and professional societies Rev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin U
Neuromedin may refer to: * Neuromedin B * Neuromedin N * Neuromedin S Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian r ... * Neuromedin U {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromedin S
Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian rhythm and also has appetite suppressant effects, as well as regulating the release of several other peptide hormones including vasopressin, luteinizing hormone, and oxytocin. See also * Neuromedin U receptor The neuromedin U receptors are two G-protein coupled receptor G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked ... References {{Neuropeptides Neuropeptides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
