Mutation In Fiction
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Mutation In Fiction
The concept of a mutant is a common trope in fiction. The new phenotypes that appear in fictional mutations generally go far beyond what is typically seen in mutants in reality, and often result in the mutated life form exhibiting superhuman abilities or qualities. DC Comics In DC Comics, the term was first used in the 1980s by a fictitious race of Extraterrestrial life, extraterrestrials known as the Dominators (DC Comics), Dominators when they appeared in the ''Invasion! (DC Comics), Invasion!'' mini-series. For instance, Captain Comet manifested his powers at birth when a comet activated his "metagene", gaining his abilities by the time he was eight. Marvel Comics In Marvel Comics, genetic mutation has been used as an explanation for super-powers since the 1950s. Mutants have played a major role in Marvel Comics, particularly the X-Men and related series. In the Marvel Universe, Marvel Comics Universe, they are a persecuted minority where most people fear and hate them. Mar ...
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Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology (physical form and structure), its developmental processes, its biochemical and physiological properties, and its behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code (its genotype) and the influence of environmental factors. Both factors may interact, further affecting the phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and again in his 1982 book '' The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as caddisfly larva cases and beaver dams ...
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Teenage Mutant Ninja Turtles (franchise)
''Teenage Mutant Ninja Turtles'' (''TMNT'') is an American media franchise created by comic book artists Kevin Eastman and Peter Laird. It follows Leonardo, Donatello, Raphael and Michelangelo, four anthropomorphic turtle brothers trained in ''ninjutsu'' who fight evil in New York City. The franchise encompasses printed media, television series, feature films, video games, and merchandise. The franchise began as a comic book, ''Teenage Mutant Ninja Turtles'', which Eastman and Laird conceived as a parody of elements popular in superhero comics at the time. The first issue was published in 1984 by Eastman and Laird's company Mirage Studios and was a surprise success. In 1987, Eastman and Laird licensed the characters to Playmates Toys, which developed a line of ''Turtles'' action figures. About US$1.1 billion of ''Turtles'' toys were sold between 1988 and 1992, making them the third-bestselling toy figures ever at the time. The action figures were promoted with an animated ...
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Leela (Futurama)
Turanga Leela is a fictional character from the List of animated television series, animated television series ''Futurama''. Leela is spaceship captain, pilot (aeronautics), pilot, and head of all aviation services on board the ''Planet Express Ship''. Throughout the series, she has an on-again, off-again relationship with Philip J. Fry, the central character in the series. The character, voiced by Katey Sagal, is named after the ''Turangalîla-Symphonie'' by Olivier Messiaen. She is one of the few characters in the cast to routinely display competence and the ability to command, and routinely saves the rest of the cast from disaster. However, she suffers extreme self-doubt because she has only one eye and grew up as a bullied orphan. She first believes herself an Extraterrestrial life in fiction, alien, but later finds out she is the least-mutated sewerage, sewer mutant (fiction), mutant in the history of 31st-century Earth. Her family (particularly her parents' accent (phon ...
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STX1A
Syntaxin-1A is a protein that in humans is encoded by the ''STX1A'' gene. Function Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the chemical synapse, presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminus, C-terminal transmembrane domain, a SNARE (protein), SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminus, N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 ...
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FOXP2
Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the ''FOXP2'' gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that Regulation of gene expression, regulate gene expression by DNA-binding protein, binding to DNA. It is expressed in the brain, heart, lungs and digestive system. ''FOXP2'' is found in many vertebrates, where it plays an important role in mimicry in birds (such as birdsong) and Animal echolocation, echolocation in bats. ''FOXP2'' is also required for the proper development of speech and language in humans. In humans, mutations in ''FOXP2'' cause the severe speech and language disorder developmental verbal dyspraxia. Studies of the gene in mice and songbirds indicate that it is necessary for vocal imitation and the related motor learning. Outside the brain, ''FOXP2'' has also been implicated in development of other tissues such as the lung and digestive system. Initially identified in 1998 as the geneti ...
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Timeless (gene)
Timeless (''tim'') is a gene in multiple species but is most notable for its role in '' Drosophila'' for encoding TIM, an essential protein that regulates circadian rhythm. ''Timeless'' mRNA and protein oscillate rhythmically with time as part of a transcription-translation negative feedback loop involving the '' period'' (''per'') gene and its protein. Discovery In 1994, ''timeless'' was discovered through forward genetic screening performed by Jeffery L. Price while working in the lab of Michael W. Young. This gene was found when they noticed an arrhythmic ''tim''01 mutant via a P element screen. The tim01 mutation caused arrhythmic behavior, defined by the lack of ability to establish proper circadian rhythms. In 1995, the timeless gene was cloned by Amita Sehgal and partners in the lab of Michael W. Young. Unlike the Drosophila ''timeless'' gene, homologs have been discovered in other species that are non-essential for circadian rhythm. The discovery of ''timeless'' fol ...
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Chromosome 7 (human)
Chromosome 7 is one of the 23 pairs of chromosomes in humans, who normally have two copies of this chromosome. Chromosome 7 spans about 160 million base pairs (the building material of DNA) and represents between 5 and 5.5 percent of the total DNA in cells. Genes Number of genes The following are some of the gene count estimates of human chromosome 7. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project ( CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Gene list The following is a partial list of genes on human chromosome 7. For complete list, see the link in the infobox on the right. Diseases and disorders The following diseases are some of those related to gene ...
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