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Motaba Virus
''Outbreak'' is a 1995 American medical disaster film directed by Wolfgang Petersen and written by Laurence Dworet and Robert Roy Pool. The film stars Dustin Hoffman, Rene Russo, Morgan Freeman and Donald Sutherland, and co-stars Cuba Gooding Jr., Kevin Spacey and Patrick Dempsey. The film focuses on an outbreak of Motaba, a fictional ''ebolavirus''- and ''orthomyxoviridae''-like virus, in Zaire, and later in a small town in California. It is set primarily in the United States Army Medical Research Institute of Infectious Diseases and the Centers for Disease Control and Prevention, as well as the fictional town of Cedar Creek, California. ''Outbreak'' plot speculates how far military and civilian agencies might go to contain the spread of a deadly, contagious disease. The film, released by Warner Bros. March 10, 1995, was a box-office success, and Spacey won two awards for his performance. A real-life outbreak of the Ebola virus was occurring in Zaire when the film was relea ...
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Wolfgang Petersen
Wolfgang Petersen (14 March 1941 – 12 August 2022) was a German film and television director, screenwriter, and producer. His international breakthrough was the 1981 war film (1981), which earned him Academy Award nominations for Best Director and Best Adapted Screenplay. He subsequently directed the blockbuster fantasy film '' The NeverEnding Story'' (1984), based on the novel of the same name. After moving to the United States in the mid-1980s, Petersen directed his first American production, the science-fiction film '' Enemy Mine'' (1985). He directed a variety of major studio productions through the mid-2000s, including '' In the Line of Fire'' (1993), ''Outbreak'' (1995), ''Air Force One'' (1997), '' The Perfect Storm'' (2000), ''Troy'' (2004), and ''Poseidon'' (2006). In addition to his Oscar nominations, Petersen won three Bambi Awards, a Bavarian Film Award, and a German Film Award. He was also a founding member of the Deutsche Filmakademie. Early life Petersen ...
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Neil Travis
Herbert Neil Travis (October 12, 1936 – March 28, 2012) was an American film and television editor with about 28 feature film credits from 1970–2007. He is likely best known for editing the television miniseries ''Roots'' (1977) and the feature film '' Dances with Wolves'' (1990). Travis was born in Los Angeles, California, and received a bachelor's degree in film and theater arts from the University of California, Los Angeles. Travis won the Primetime Emmy Award for Outstanding Film Editing In A Drama Series for the first part of the television miniseries ''Roots'' (1977), and he and James Heckert were nominated for the award for the second part as well. Travis won the Academy Award for Best Film Editing and the American Cinema Editors Eddie for the film '' Dances with Wolves'' (directed by Kevin Costner-1990). Travis had been selected as a member of the American Cinema Editors, and received the Career Achievement Award in 2010. In 2010, Travis was interviewed about ...
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Viral Hemorrhagic Fever
Viral hemorrhagic fevers (VHFs) are a diverse group of diseases. "Viral" means a health problem caused by infection from a virus, " hemorrhagic" means to bleed, and "fever" means an unusually high body temperature. Bleeding and fever are common signs of VHFs, which is how the group of infections got its common name. There are five known families of RNA viruses which cause VHFs: '' Arenaviridae'', '' Filoviridae'', '' Flaviviridae'', '' Hantaviridae'', and ''Rhabdoviridae''. Some VHFs are usually mild, such as nephropathia epidemica (within the family ''Hantaviridae''). But some are usually severe and have a high death rate, such as Ebola virus (within the family ''Filoviridae''). All VHFs can potentially cause severe blood loss, high fever, and death. Both humans and non human animals can be infected. Signs and symptoms The following are signs and symptoms of most or all VHFs. * Circulatory shock *Diarrhea (feces which resemble more liquid than solid) *Headache *Hypotens ...
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Stanleyville Mutinies
The Stanleyville mutinies, also known as the Mercenaries' mutinies, occurred in the Democratic Republic of the Congo in 1966 and 1967. First mutiny Amid rumours that the ousted prime minister Moïse Tshombe was plotting a comeback from his exile in Spain, some 2,000 of Tshombe's former Katangan gendarmes, led by mercenaries, mutinied in Kisangani (formerly Stanleyville) in July 1966. Lieutenant-Colonel Joseph-Damien Tshatshi, the local military commander, was executed. The mutiny was unsuccessful and was crushed. Second mutiny Exactly a year after the failure of the first mutiny, another broke out, again in Kisangani, apparently triggered by the news that Tshombe's airplane had been hijacked over the Mediterranean and forced to land in Algiers, where he was held prisoner. Led by a Belgian settler/mercenary named Jean Schramme with fellow mercenaries Bob Denard and Jerry Puren (all 3 had fought for Tshombe in Katanga and the Congo) and involving approximately 100 former Katang ...
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Joshua Lederberg
Joshua Lederberg (May 23, 1925 – February 2, 2008) was an American molecular biology, molecular biologist known for his work in microbial genetics, artificial intelligence, and the United States space program. He was 33 years old when he won the 1958 Nobel Prize in Physiology or Medicine for discovering that bacteria can mate and exchange genes (bacterial conjugation). He shared the prize with Edward Tatum and George Beadle, who won for their work with genetics. In addition to his contributions to biology, Lederberg did extensive research in artificial intelligence. This included work in the NASA experimental programs seeking life on Mars and the chemistry expert system Dendral. Early life and education Lederberg was born in Montclair, New Jersey, to a Jewish family, son of Esther Goldenbaum Schulman Lederberg and Rabbi Zvi Hirsch Lederberg, in 1925, and moved to Washington Heights, Manhattan as an infant. He had two younger brothers. Lederberg graduated from Stuyvesant High S ...
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COVID-19 Pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and COVID-19 pandemic by country and territory, then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March. COVID-19 symptoms range from asymptomatic to deadly, but most commonly include fever, sore throat, nocturnal cough, and fatigue. Transmission of COVID-19, Transmission of the virus is often airborne transmission, through airborne particles. Mutations have variants of SARS-CoV-2, produced many strains (variants) with varying degrees of infectivity and virulence. COVID-19 vaccines were developed rapidly and deplo ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United States Department of Health and Human Services, Department of Health and Human Services (HHS), and is headquartered in Atlanta, Georgia. The CDC's current nominee for director is Susan Monarez. She became acting director on January 23, 2025, but stepped down on March 24, 2025 when nominated for the director position. On May 14, 2025, Robert F. Kennedy Jr. stated that lawyer Matthew Buzzelli is acting CDC director. However, the CDC web site does not state the acting director's name. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It e ...
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United States Army Medical Research Institute Of Infectious Diseases
The United States Army Medical Research Institute of Infectious Diseases (USAMRIID; ) is the United States Army's main institution and facility for defensive research into countermeasures against biological warfare. It is located on Fort Detrick, Maryland, near Washington, D.C., and is a subordinate lab of the United States Army Medical Research and Development Command (USAMRDC), headquartered on the same installation. USAMRIID is the only laboratory of the United States Department of Defense (DoD) equipped to study highly hazardous viruses at Biosafety Level 4 within positive pressure personnel suits. USAMRIID employs both military and civilian scientists as well as highly specialized support personnel, totaling around 800 people. In the 1950s and 1960s, USAMRIID and its predecessor unit pioneered unique, state-of-the-art biocontainment facilities which it continues to maintain and upgrade. Investigators at its facilities frequently collaborate with the Centers for ...
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California
California () is a U.S. state, state in the Western United States that lies on the West Coast of the United States, Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares Mexico–United States border, an international border with the Mexico, Mexican state of Baja California to the south. With almost 40million residents across an area of , it is the List of states and territories of the United States by population, largest state by population and List of U.S. states and territories by area, third-largest by area. Prior to European colonization of the Americas, European colonization, California was one of the most culturally and linguistically diverse areas in pre-Columbian North America. European exploration in the 16th and 17th centuries led to the colonization by the Spanish Empire. The area became a part of Mexico in 1821, following Mexican War of Independence, its successful war for independence, but Mexican Cession, was ceded to the U ...
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Zaire
Zaire, officially the Republic of Zaire, was the name of the Democratic Republic of the Congo from 1971 to 18 May 1997. Located in Central Africa, it was, by area, the third-largest country in Africa after Sudan and Algeria, and the 11th-largest country in the world from 1965 to 1991. With a population of over 23 million, Zaire was the most populous Francophone country in Africa. Zaire was strategically important to the West during the Cold War, particularly the U.S., as a counterbalance to Soviet influence in Africa. The U.S. and its allies supported the Mobutu regime (1965–1997) with military and economic aid to prevent the spread of communism. The country was a one-party totalitarian military dictatorship, run by Mobutu Sese Seko and his Popular Movement of the Revolution. Zaire was established following Mobutu's seizure of power in a military coup in 1965, after five years of political upheaval following independence from Belgium known as the Congo Crisis. Zaire ...
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Orthomyxoviridae
''Orthomyxoviridae'' () is a family of negative-sense single-stranded RNA virus, negative-sense RNA viruses. It includes nine genus, genera: ''Influenza A virus, Alphainfluenzavirus'', ''Influenza B virus, Betainfluenzavirus'', ''Influenza C virus, Gammainfluenzavirus'', ''Influenza D virus, Deltainfluenzavirus'', ''Isavirus'', ''Mykissvirus'', ''Quaranjavirus'', ''Sardinovirus'', and ''Thogotovirus''. The first four genera contain viruses that cause influenza in birds (see also avian influenza) and mammals, including humans. Isaviruses infect salmon; the thogotoviruses are arboviruses, infecting vertebrates and invertebrates (such as ticks and mosquitoes). The Quaranjaviruses are also arboviruses, infecting vertebrates (birds) and invertebrates (arthropods). The four genera of Influenza virus that infect vertebrates, which are identified by antigenic differences in their nucleoprotein and matrix protein, are as follows: * ''Influenza A virus, Alphainfluenzavirus'' infects huma ...
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Ebolavirus
The genus ''Ebolavirus'' (- or ; - or ) is a International Committee on Taxonomy of Viruses, virological taxon included in the family ''Filoviridae'' (filament-shaped viruses), order ''Mononegavirales''. The members of this genus are called ebolaviruses, and encode their genome in the form of RNA virus#Group V—negative-sense ssRNA viruses, single-stranded negative-sense RNA. The six known virus International Committee on Taxonomy of Viruses, species are named for the region where each was originally identified: ''Bundibugyo ebolavirus'', ''Reston ebolavirus'', ''Sudan ebolavirus'', ''Taï Forest ebolavirus'' (originally ''Côte d'Ivoire ebolavirus''), ''Zaire ebolavirus'', and ''Bombali ebolavirus''. The last is the most recent species to be named and was isolated from Angolan free-tailed bats in Sierra Leone. Each species of the genus ''Ebolavirus'' has one member virus, and four of these cause Ebola virus disease (EVD) in humans, a type of Viral hemorrhagic fever, hemorrhagic ...
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