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Micrurus Mipartitus
''Micrurus mipartitus'' (red-tailed coral snake or many-banded coral snake) is a species of coral snake in the family Elapidae. It is found in South and Central America. The redtail coral snake is common in agricultural areas in Colombia. Its highly neurotoxic venom is known to cause seizures in its prey by activating nerve proteins responsible for seizures within it. Subspecies Five subspecies are currently recognized: Phenotypic features ''Micrurus mipartitus'' has a cylindrical body that can reach up to 140.6 centimeters in length. They have quite small eyes upon their round heads. The black bodily rings of this species can range anywhere from 34 to 84 and are sundered by yellow or white intermediaries. The second ring on the head and 3 or 4 of the tail rings exude a red color in contrast to the white or yellow bands. Natural history ''Micrurus mipartitus'' is a species of crepuscular and nocturnal habits. During period of low rainfall, could be located underground sev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
André Marie Constant Duméril
André Marie Constant Duméril (1 January 1774 – 14 August 1860) was a French zoologist. He was professor of anatomy at the Muséum national d'histoire naturelle from 1801 to 1812, when he became professor of herpetology and ichthyology. His son Auguste Duméril was also a zoologist. Life André Marie Constant Duméril was born on 1 January 1774 in Amiens and died on 14 August 1860 in Paris. He became a doctor at a young age, obtaining, at 19 years, the ''prévot'' of anatomy at the medical school of Rouen. In 1800, he left for Paris and collaborated in the drafting of the comparative anatomy lessons of Georges Cuvier. He replaced Cuvier at the Central School of the Panthéon and had, as his colleague, Alexandre Brongniart. In 1801, he gave courses to the medical school of Paris. Under the ''Restauration'', he was elected a member of the Académie des Sciences (French Academy of Sciences) and after 1803 succeeded Lacépède, who was occupied by his political o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lizard
Lizards are a widespread group of squamate reptiles, with over 7,000 species, ranging across all continents except Antarctica, as well as most oceanic island chains. The group is paraphyletic since it excludes the snakes and Amphisbaenia although some lizards are more closely related to these two excluded groups than they are to other lizards. Lizards range in size from chameleons and geckos a few centimeters long to the 3-meter-long Komodo dragon. Most lizards are quadrupedal, running with a strong side-to-side motion. Some lineages (known as " legless lizards"), have secondarily lost their legs, and have long snake-like bodies. Some such as the forest-dwelling '' Draco'' lizards are able to glide. They are often territorial, the males fighting off other males and signalling, often with bright colours, to attract mates and to intimidate rivals. Lizards are mainly carnivorous, often being sit-and-wait predators; many smaller species eat insects, while the Komodo eats mamma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicotinic Acetylcholine Receptor
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of many organisms. At the neuromuscular junction they are the primary receptor in muscle for motor nerve-muscle communication that controls muscle contraction. In the peripheral nervous system: (1) they transmit outgoing signals from the presynaptic to the postsynaptic cells within the sympathetic and parasympathetic nervous system, and (2) they are the receptors found on skeletal muscle that receive acetylcholine released to signal for muscular contraction. In the immune system, nAChRs regulate inflammatory processes and signal through distinct intracellular pathways. In insects, the cholinergic system is limited to the central nervous system. The nicotinic receptors are considered choline ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mipartoxin-I
Mipartoxin-I is a neurotoxin produced by ''Micrurus mipartitus'', a venomous coral snake distributed in Central and South America. This toxin causes a neuromuscular blockade by blocking the nicotinic acetylcholine receptor. It is the most abundant component in the venom. Sources The toxin is produced by the ''Micrurus mipartitus'', also known as the ‘redtail coral snake’, ‘''rabo de ají''’, or ‘''gargantilla''’. The snake populates Nicaragua, Costa Rica, isthmus of Panama, Ecuador, Colombia, Venezuela and Brazil. Chemistry Structure and family Mipartoxin-I is a short-chain, type-I, α-neurotoxin composed of 60 amino acids with a molecular mass of 7030 Da. It is a member of the three finger toxin (3FTx) superfamily, and it contains the characteristic eight cysteines of this superfamily. Homology CTX A5, a cardiotoxin Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. The heart becomes weaker a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phospholipase A2
The enzyme phospholipase A2 (EC 3.1.1.4, PLA2, systematic name phosphatidylcholine 2-acylhydrolase) catalyse the cleavage of fatty acids in position 2 of phospholipids, hydrolyzing the bond between the second fatty acid “tail” and the glycerol molecule: :phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate This particular phospholipase specifically recognizes the ''sn''2 acyl bond of phospholipids and catalytically hydrolyzes the bond, releasing arachidonic acid and lysophosphatidic acid. Upon downstream modification by cyclooxygenases or lipoxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as anti-inflammatory and inflammatory mediators. PLA2 enzymes are commonly found in mammalian tissues as well as arachnid, insect, and snake venom. Venom from bees is largely composed of melittin, which is a stimulant of PLA2. Due to the increa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Three-finger Toxin
Three-finger toxins (abbreviated 3FTx) are a protein superfamily of small toxin proteins found in the venom of snakes. Three-finger toxins are in turn members of a larger superfamily of three-finger protein domains which includes non-toxic proteins that share a similar protein fold. The group is named for its common structure consisting of three beta strand loops connected to a central core containing four conserved disulfide bonds. The 3FP protein domain has no enzymatic activity and is typically between 60-74 amino acid residues long. Despite their conserved structure, three-finger toxin proteins have a wide range of pharmacological effects. Most members of the family are neurotoxins that act on cholinergic intercellular signaling; the alpha-neurotoxin family interacts with muscle nicotinic acetylcholine receptors (nAChRs), the kappa-bungarotoxin family with neuronal nAChRs, and muscarinic toxins with muscarinic acetylcholine receptors (mAChRs). Structure The three-finger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IUCN Redlist
The International Union for Conservation of Nature (IUCN) Red List of Threatened Species, also known as the IUCN Red List or Red Data Book, founded in 1964, is the world's most comprehensive inventory of the global conservation status of biological species. It uses a set of precise criteria to evaluate the extinction risk of thousands of species and subspecies. These criteria are relevant to all species and all regions of the world. With its strong scientific base, the IUCN Red List is recognized as the most authoritative guide to the status of biological diversity. A series of Regional Red Lists are produced by countries or organizations, which assess the risk of extinction to species within a political management unit. The aim of the IUCN Red List is to convey the urgency of conservation issues to the public and policy makers, as well as help the international community to reduce species extinction. According to IUCN the formally stated goals of the Red List are to provide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Micrurus Multifasciatus
''Micrurus'' is a genus of venomous coral snakes of the family Elapidae. Geographic range Species in the genus ''Micrurus'' are endemic to the Americas. Species The following 83 species are recognized as being valid. *'' Micrurus albicinctus'' Amaral, 1925 *'' Micrurus alleni'' K. Schmidt, 1936 *'' Micrurus altirostris'' ( Cope, 1860) *''Micrurus ancoralis'' Jan, 1872 *'' Micrurus annellatus'' W. Peters, 1871 *'' Micrurus averyi'' K. Schmidt, 1939 *'' Micrurus baliocoryphus'' (Cope, 1862) *'' Micrurus bernadi'' (Cope, 1887) *'' Micrurus bocourti'' (Jan, 1872) *'' Micrurus bogerti'' Roze, 1967 *'' Micrurus boicora'' *''Micrurus brasiliensis'' Roze, 1967 *'' Micrurus browni'' K. Schmidt & H.M. Smith, 1943 *'' Micrurus carvalhoi'' Roze, 1967 *'' Micrurus camilae'' Renjifo & Lundberg, 2003 *'' Micrurus circinalis'' ( A.M.C. Duméril, Bibron & A.H.A. Duméril, 1854) *'' Micrurus clarki'' K. Schmidt, 1936 *''Micrurus collaris'' ( Schlegel, 1837) *'' Micrurus corallinus'' ( Mer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caecilia Guntheri
''Caecilia guntheri'' is a species of caecilian in the family Caeciliidae. It is found in Colombia and Ecuador. Its natural habitat is subtropical or tropical moist montane forest Montane ecosystems are found on the slopes of mountains. The alpine climate in these regions strongly affects the ecosystem because temperatures fall as elevation increases, causing the ecosystem to stratify. This stratification is a crucia ...s. References guntheri Amphibians of Colombia Amphibians of Ecuador Amphibians described in 1942 Taxonomy articles created by Polbot {{Caeciliidae-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caecilian
Caecilians (; ) are a group of limbless, vermiform or serpentine amphibians. They mostly live hidden in the ground and in stream substrates, making them the least familiar order of amphibians. Caecilians are mostly distributed in the tropics of South and Central America, Africa, and southern Asia. Their diet consists of small subterranean creatures such as earthworms. All modern caecilians and their closest fossil relatives are grouped as a clade, Apoda , within the larger group Gymnophiona , which also includes more primitive extinct caecilian-like amphibians. The name derives from the Greek words γυμνος (''gymnos'', naked) and οφις (''ophis'', snake), as the caecilians were originally thought to be related to snakes. The body is cylindrical dark brown or bluish black in colour. The skin is slimy and bears grooves or ringlike markings. Description Caecilians completely lack limbs, making the smaller species resemble worms, while the larger species, with lengths ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frog
A frog is any member of a diverse and largely carnivorous group of short-bodied, tailless amphibians composing the order Anura (ανοὐρά, literally ''without tail'' in Ancient Greek). The oldest fossil "proto-frog" '' Triadobatrachus'' is known from the Early Triassic of Madagascar, but molecular clock dating suggests their split from other amphibians may extend further back to the Permian, 265 million years ago. Frogs are widely distributed, ranging from the tropics to subarctic regions, but the greatest concentration of species diversity is in tropical rainforest. Frogs account for around 88% of extant amphibian species. They are also one of the five most diverse vertebrate orders. Warty frog species tend to be called toads, but the distinction between frogs and toads is informal, not from taxonomy or evolutionary history. An adult frog has a stout body, protruding eyes, anteriorly-attached tongue, limbs folded underneath, and no tail (the tail of tailed frogs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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