HOME



picture info

Melanistic Mask
A melanistic mask (also referred to as a mask or masking) is a dog coat pattern that gives the appearance of a mask on the dog's face. The hairs on the muzzle, and sometimes entire face or ears, are colored by eumelanin instead of pheomelanin pigment. Eumelanin is typically black, but may instead be brown, dark gray, or light gray-brown. Pheomelanin ranges in color from pale cream to mahogany. The trait is caused by M264V (''EM''), a completely dominant allele (form) of the melanocortin 1 receptor gene. Appearance At minimum, a melanistic mask will appear on the muzzle, and may also be visible on the eartips, entire ears, or entire face. Hairs in those areas will be colored by eumelanin instead of pheomelanin pigment, making it look as though the dog has a mask on its face. Eumelanin is usually black, but may instead be liver (also known as chocolate; dark brown), blue (also known as slate; dark grey), or isabella (also known as lilac; light grey-brown); accordingly, a mask m ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Pug Portrait
The Pug is a breed of dog with the physically distinctive features of a wrinkly, short-muzzled face, and curled tail. An ancient breed, with roots dating back to 400 B.C., they have a fine, glossy coat that comes in a variety of colors, most often fawn (light brown) or black, and a compact, square body with well developed and thick muscles all over the body. Pugs were brought from China to Europe in the sixteenth century and were popularized in Western Europe by the House of Orange of the Netherlands, and the House of Stuart. In the United Kingdom, in the nineteenth century, Queen Victoria developed a passion for Pugs which she passed on to other members of the royal family. Pugs are known for being sociable and gentle companion dogs. The American Kennel Club describes the breed's personality as "even-tempered and charming". Pugs remain popular into the twenty-first century, with some famous celebrity owners. The dogs are susceptible to various health problems due to their b ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Brindle
Brindle is a coat (animal), coat coloring pattern in animals, particularly dogs, cattle, guinea pigs, cats, and, rarely, horses. It is sometimes described as "tiger-striped", although the brindle pattern is more subtle than that of a tiger's coat. Brindle typically appears as black stripes on a red base. The stripes are eumelanin (black/brown pigment) and the base is phaeomelanin (red/yellow pigment), so the appearance of those pigments can be changed by any of the genes which usually affect them. * Eumelanin (the pigment making up the stripes) can be affected by: merle (and harlequin), liver, dilution, greying, and recessive red. * Phaeomelanin (the pigment making up the base) can be affected by: Intensity locus. White markings and ticking can occur on any brindle dog. Brindle is caused by a complex gene process and is technically a form of mosaicism, where some cells express one allele (KB) and other cells express a different allele (ky), a little like tortoiseshell cats. ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Dog Anatomy
Dog anatomy comprises the anatomical study of the visible parts of the body of a dog, domestic dog. Details of structures vary tremendously from dog breed, breed to breed, more than in any other animal species, wild or domesticated, as dogs are highly variable in height and weight. The smallest known adult dog was a Yorkshire Terrier that stood only at the shoulder, in length along the head and body, and weighed only . The heaviest dog was an English Mastiff named Zorba (dog), Zorba, which weighed . The tallest known adult dog is a Great Dane that stands at the shoulder. Anatomy Muscles The following is a list of the muscles in the dog, along with their origin, insertion, action and innervation. Extrinsic muscles of the thoracic limb and related structures: Descending superficial pectoral: originates on the first sternebrae and inserts on the greater tubercle of the humerus. It both adducts the limb and also prevents the limb from being abducted during weight bearing. It i ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Border Collie
The Border Collie is a British list of dog breeds, breed of herding dog of the collie type of medium size. It originates in the region of the Anglo-Scottish border, and descends from the traditional Sheep dog, sheepdogs once found all over the British Isles. It is kept mostly as a working sheep-herding dog or as a companion animal. It competes with success in sheepdog trials. It has been claimed that it is the canine intelligence, most intelligent breed of dog. History The Border Collie is descended from landrace collies, a type found widely in the British Isles. The name for the breed came from its probable place of origin along the Anglo-Scottish border. Mention of the "collie" or "Colley" type first appeared toward the end of the 19th century, although the word "collie" is older than this and has its origin in the Scots language. It is also thought that the word 'collie' comes from the old Celtic word for useful. Many Border Collies today can be traced back to a dog known as ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Kerry Blue Terrier
The Kerry Blue Terrier (also known as the Irish Blue Terrier) () is a breed of dog. Originally bred to control vermin including rats, rabbits, badgers, ferrets, foxes, otters, hares, deer, and even wolves, over time the Kerry became a general working dog used for a variety of jobs including herding cattle and sheep. Despite a Kerry Blue winning Crufts (the most prestigious UK dog show) in 2000, it remains an "unfashionable" breed, and is distinctly uncommon; however, it is not as threatened as some of the other terrier breeds such as the Skye Terrier, Sealyham Terrier, and Dandie Dinmont Terrier. Description Appearance Some characteristics of the Kerry Blue Terrier include a long head, flat skull, deep chest, and a soft wavy-to-curly coat that comes in several shades of "blue", the general term outside this breed being progressive grey. Puppies are born black; the blue appears gradually as the puppy grows older, usually up to 2 years of age. The male Kerry Blue is usually ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Dogue De Bordeaux
The Dogue de Bordeaux, also known as the Bordeaux Mastiff, French Mastiff or Bordeauxdog, is a large French mastiff breed. A typical brachycephalic mastiff breed, the Bordeaux is a very powerful dog, with a very muscular body. History The Dogue de Bordeaux was known in France as early as the 14th century, particularly in southern France in the region around Bordeaux. Hence, the city lent its name to this large dog. The breed was first exhibited in France in 1863 after which time it gained in popularity not only in their home country but in other parts of the world. The first record of the Dogue de Bordeaux in the UK can be seen in the Kennel Club Gazette in 1897. The breed received championship status with the Kennel Club (UK) in 2016. A uniform breed type of the Bordeaux dog did not exist before about 1920. The history of the breed is believed to predate the Bullmastiff and the Bulldog. It is said that the Dogue can be found in the background of the Bullmastiff, and other ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Whippet
The Whippet is a British breed of dog of sighthound type. It closely resembles the Greyhound and the smaller Italian Greyhound, and is intermediate between them in size. In the nineteenth century it was sometimes called "the poor man's racehorse". It is commonly kept as a companion dog, for competitive showing or for amateur racing, and may participate in various dog sports, including lure coursing, agility, and flyball. It has the fastest running speed within its weight and size range, and is believed to have the fastest idle-to-running acceleration of any dog. Whippets are characterized by their gentle, affectionate, and calm temperament. While typically relaxed and serene at home, they exhibit high energy and excitement when outdoors. Originally bred as hunting and racing dogs, Whippets have a strong prey drive, which may lead them to chase small animals. Whippets have a minimal-shedding coat that is easy to manage due to its short, smooth texture and lack of an unde ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Agouti Gene
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. It is responsible for the distribution of melanin pigment in mammals. Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). This interaction is responsible for making distinct light and dark bands in the hairs of animals such as the agouti, which the gene is named after. In other species such as horses, agouti signalling is responsible for determining which parts of the body will be red or black. Mice with wildtype agouti will be grey-brown, with each hair being partly yellow and partly black. Loss of function mutations in mice and other species cause black fur coloration, while mutations causing expression throughout the whole body in mice cause yellow fur and obesity. The agouti-signaling protein (ASIP) is a competitive antagonist with alpha-Melanocyte-stimulat ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Melanocyte-stimulating Hormone
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary gland. Organic compound#Synthetic compounds, Synthetic analog (chemistry), analogues of α-MSH, such as afamelanotide (melanotan I; Scenesse), melanotan II, and bremelanotide (PT-141), have been developed and researched. Biosynthesis The various forms of MSH are generated from different cleavages of the proopiomelanocortin protein, which also yields other important neuropeptides like adrenocorticotropic hormone. Melanocytes in skin make and secrete MSH in response to ultraviolet light, where it increases synthesis of melanin. Some neurons in arcuate nucleus of the hypothalamus make an ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


UC Davis School Of Veterinary Medicine
The University of California, Davis, School of Veterinary Medicine is the largest veterinary school in the United States. Established in 1948, the school is the primary health resource for California's animal populations. In 2020, the school was again ranked first in the United States by '' U.S. News & World Report'' and in 2022, ranked second in the world by QS World University Rankings. The school is located in the southwest corner of the main campus of the University of California, Davis. The current dean of veterinary medicine is Dr. Mark Stetter. The school focuses on students of the professional Doctor of Veterinary Medicine program, the Master of Preventive Veterinary Medicine program, graduate clinical residency programs, and graduate academic MS and PhD programs. The School of Veterinary Medicine provides educational, research, clinical service, and public service programs to advance the health and care of animals, the health of the environment, and public health. The sch ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Locus (genetics)
In genetics, a locus (: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of Human genome#Coding sequences (protein-coding genes), protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygote, homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygote, heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association ma ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]