|
Maximilian Von Frey
Maximilian (Max) Ruppert Franz von Frey (16 November 1852 – 25 January 1932) was an Austrian-German physiologist who was born in Salzburg. He received his doctorate from the University of Leipzig in 1877, and subsequently worked at Carl Ludwig's Physiological Institute in Leipzig. Later he was a professor of physiology at the Universities of Würzburg and Zurich. Frey's primary work in Leipzig dealt with the circulatory system, and he is credited with developing an early prototype of a heart-lung machine. He is remembered for his work involving cutaneous sensory mechanoreceptors. During the 1890s, Frey proposed that pain is an independent tactile quality, alongside touch, heat and cold, and that it is associated with stimulation of high-threshold free nerve endings. He described the skin as a mosaic of discrete spots, each sensitive to one or another of these stimuli. He created a unique type of esthesiometer An esthesiometer (British spelling aesthesiometer) is a device for m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ systems, individual organ (biology), organs, cell (biology), cells, and biomolecules carry out chemistry, chemical and physics, physical functions in a living system. According to the classes of organisms, the field can be divided into clinical physiology, medical physiology, Zoology#Physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysics, biophysical and biochemical processes, homeostasis, homeostatic control mechanisms, and cell signaling, communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathology, pathological state'' refers to abnormality (behavior), abnormal conditions, including human diseases. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mechanoreceptor
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are located on sensory neurons that convert mechanical pressure into action potential, electrical signals that, in animals, are sent to the central nervous system. Vertebrate mechanoreceptors Cutaneous mechanoreceptors Cutaneous mechanoreceptors respond to mechanical stimuli that result from physical interaction, including pressure and vibration. They are located in the skin, like other cutaneous receptors. They are all innervated by Aβ fibers, except the mechanorecepting free nerve endings, which are innervated by A delta fiber, Aδ fibers. Cutaneous mechanoreceptors can be categorized by what kind of sensation they perceive, by the rate of adaptation, and by morphology. Furthermore, each has a different receptive field. By sensation * The Slowly Adapting type 1 (SA1) mechanoreceptor, with the Merkel corpuscle end-organ (also known as M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of The University Of Würzburg
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of tertiary education. The name traces back to Plato's school of philosophy, founded approximately 386 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. The Royal Spanish Academy defines academy as scientific, literary or artistic society established with public authority and as a teaching establishment, public or private, of a professional, artistic, technical or simply practical nature. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physicians From Salzburg
A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Medical diagnosis, diagnosis, prognosis and therapy, treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as Specialty (medicine), specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practitioner, general practice. Medical practice properly requires both a detailed knowledge of the Discipline (academia), academic disciplines, such as anatomy and physiology, pathophysiology, underlying diseases, and their treatment, which is the science of medicine, and a decent Competence (human resources ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Physiologists
German(s) may refer to: * Germany, the country of the Germans and German things **Germania (Roman era) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizenship in Germany, see also German nationality law **Germanic peoples (Roman era) *German diaspora * German language * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (disambigu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1932 Deaths
Events January * January 4 – The British authorities in India arrest and intern Mahatma Gandhi and Vallabhbhai Patel. * January 9 – Sakuradamon Incident (1932), Sakuradamon Incident: Korean nationalist Lee Bong-chang fails in his effort to assassinate Emperor Hirohito of Japan. The Kuomintang's official newspaper runs an editorial expressing regret that the attempt failed, which is used by the Japanese as a pretext to attack Shanghai later in the month. * January 22 – The 1932 Salvadoran peasant uprising begins; it is suppressed by the government of Maximiliano Hernández Martínez. * January 24 – Marshal Pietro Badoglio declares the end of Libyan resistance. * January 26 – British submarine aircraft carrier sinks with the loss of all 60 onboard on exercise in Lyme Bay in the English Channel. * January 28 – January 28 incident: Conflict between Japan and China in Shanghai. * January 31 – Japanese warships arrive in Nanking. February * February 2 ** A general ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1852 Births
Events January–March * January 14 – President Napoleon III, Louis-Napoléon Bonaparte proclaims a French Constitution of 1852, new constitution for the French Second Republic. * January 15 – Nine men representing various Jewish charitable organizations come together to form what will become Mount Sinai Hospital, New York, Mount Sinai Hospital in New York City. * January 17 – The United Kingdom recognizes the independence of the South African Republic, Transvaal. * February 3 – Battle of Caseros, Argentina: The Argentine provinces of Entre Ríos Province, Entre Rios and Corrientes, allied with Brazil and members of Colorado Party (Uruguay), Colorado Party of Uruguay, defeat Buenos Aires troops under Juan Manuel de Rosas. * February 11 – The first British public toilet for women opens in Bedford Street, London. * February 14 – The Great Ormond Street Hospital for Sick Children, London, admits its first patient. * February 15 – ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monofilament Fishing Line
Monofilament fishing line (shortened to just mono) is fishing line made from a single fiber of plastic material, as opposed to multifilament or braided fishing lines constructed from multiple strands of fibers. Most fishing lines are now nylon monofilament because they are cheap to manufacture and can be produced in a range of diameters which have different tensile strengths (called "tests" after the process of tensile testing, or possibly as a portmanteau of "tensile" and "strength"). Monofilament line is also available in different colors, such as clear, white, green, blue, red, and fluorescent. Monofilament is made by melting and mixing polymers and then extruding the mixture through tiny holes, forming strands of line, which is then spun into spools of various thicknesses. The extrusion process controls not only the thickness of the line but its test as well. History DuPont made public in 1938 that their company had invented nylon. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Von Frey Hair
An esthesiometer (British spelling aesthesiometer) is a device for measuring the tactile sensitivity of the skin (or mouth, or eye, etc.). The measure of the degree of tactile sensitivity is called aesthesiometry. The device was invented by Edward Henry Sieveking. There are different types of aesthesiometers depending on their particular function. Two-point discrimination The simplest is a manual tool with adjustable points similar to a caliper. It can determine how short a distance between two impressions on the skin can be distinguished. To differentiate between two points and one point of equal area (the sum of the areas of the two points equals the area of the third point), Dr. Sidney Weinstein created the three-point esthesiometer. A scale on the instrument gives readings in millimeter gradients. Monofilaments Another type of manual aesthesiometer is used to test lower thresholds of touch or pain. The tool uses nylon monofilaments with varying calibrated diameters. The fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Free Nerve Ending
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. ''Afferent'' in this case means bringing information from the body's periphery toward the brain. They function as cutaneous nociceptors and are essentially used by vertebrates to detect noxious stimuli that often result in pain. Structure Free nerve endings are unencapsulated and have no complex sensory structures. They are the most common type of nerve ending, and are most frequently found in the skin. They penetrate the dermis and end in the stratum granulosum. FNEs infiltrate the middle layers of the dermis and surround hair follicles. Types Free nerve endings have different rates of adaptation, stimulus modalities, and fiber types. Rate of adaptation Different types of FNE can be rapidly adapting, intermediate adapting, or slowly adapting. A delta type II fibers are fast-adapting while A delta type I and C fibers are slowly adapting. Modali ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolphins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
